These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 33520242)

  • 1. Joint neutron/X-ray crystal structure of a mechanistically relevant complex of perdeuterated urate oxidase and simulations provide insight into the hydration step of catalysis.
    McGregor L; Földes T; Bui S; Moulin M; Coquelle N; Blakeley MP; Rosta E; Steiner RA
    IUCrJ; 2021 Jan; 8(Pt 1):46-59. PubMed ID: 33520242
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Large crystal growth by thermal control allows combined X-ray and neutron crystallographic studies to elucidate the protonation states in Aspergillus flavus urate oxidase.
    Oksanen E; Blakeley MP; Bonneté F; Dauvergne MT; Dauvergne F; Budayova-Spano M
    J R Soc Interface; 2009 Oct; 6 Suppl 5(Suppl 5):S599-610. PubMed ID: 19586953
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Near-atomic resolution structures of urate oxidase complexed with its substrate and analogues: the protonation state of the ligand.
    Gabison L; Chiadmi M; El Hajji M; Castro B; Colloc'h N; Prangé T
    Acta Crystallogr D Biol Crystallogr; 2010 Jun; 66(Pt 6):714-24. PubMed ID: 20516624
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Azide inhibition of urate oxidase.
    Gabison L; Colloc'h N; Prangé T
    Acta Crystallogr F Struct Biol Commun; 2014 Jul; 70(Pt 7):896-902. PubMed ID: 25005084
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The neutron structure of urate oxidase resolves a long-standing mechanistic conundrum and reveals unexpected changes in protonation.
    Oksanen E; Blakeley MP; El-Hajji M; Ryde U; Budayova-Spano M
    PLoS One; 2014; 9(1):e86651. PubMed ID: 24466188
    [TBL] [Abstract][Full Text] [Related]  

  • 6. X-ray, ESR, and quantum mechanics studies unravel a spin well in the cofactor-less urate oxidase.
    Gabison L; Chopard C; Colloc'h N; Peyrot F; Castro B; El Hajji M; Altarsha M; Monard G; Chiadmi M; Prangé T
    Proteins; 2011 Jun; 79(6):1964-76. PubMed ID: 21491497
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neutron and X-ray crystal structures of a perdeuterated enzyme inhibitor complex reveal the catalytic proton network of the Toho-1 β-lactamase for the acylation reaction.
    Tomanicek SJ; Standaert RF; Weiss KL; Ostermann A; Schrader TE; Ng JD; Coates L
    J Biol Chem; 2013 Feb; 288(7):4715-22. PubMed ID: 23255594
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Complexed and ligand-free high-resolution structures of urate oxidase (Uox) from Aspergillus flavus: a reassignment of the active-site binding mode.
    Retailleau P; Colloc'h N; Vivarès D; Bonneté F; Castro B; El-Hajji M; Mornon JP; Monard G; Prangé T
    Acta Crystallogr D Biol Crystallogr; 2004 Mar; 60(Pt 3):453-62. PubMed ID: 14993669
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: mechanistic implications.
    Gabison L; Prangé T; Colloc'h N; El Hajji M; Castro B; Chiadmi M
    BMC Struct Biol; 2008 Jul; 8():32. PubMed ID: 18638417
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Urate oxidase from Aspergillus flavus: new crystal-packing contacts in relation to the content of the active site.
    Retailleau P; Colloc'h N; Vivarès D; Bonneté F; Castro B; El Hajji M; Prangé T
    Acta Crystallogr D Biol Crystallogr; 2005 Mar; 61(Pt 3):218-29. PubMed ID: 15735331
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Polymorphism of microcrystalline urate oxidase from Aspergillus flavus.
    Collings I; Watier Y; Giffard M; Dagogo S; Kahn R; Bonneté F; Wright JP; Fitch AN; Margiolaki I
    Acta Crystallogr D Biol Crystallogr; 2010 May; 66(Pt 5):539-48. PubMed ID: 20445229
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Catalytic Mechanisms for Cofactor-Free Oxidase-Catalyzed Reactions: Reaction Pathways of Uricase-Catalyzed Oxidation and Hydration of Uric Acid.
    Wei D; Huang X; Qiao Y; Rao J; Wang L; Liao F; Zhan CG
    ACS Catal; 2017 Jul; 7(7):4623-4636. PubMed ID: 28890842
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Strengthening intersubunit hydrogen bonds for enhanced stability of recombinant urate oxidase from Aspergillus flavus: molecular simulations and experimental validation.
    Liu Z; Lu D; Li J; Chen W; Liu Z
    Phys Chem Chem Phys; 2009 Jan; 11(2):333-40. PubMed ID: 19088989
    [TBL] [Abstract][Full Text] [Related]  

  • 14. On the Permeation by Dioxygen of Urate Oxidase from Aspergillus flavus in Complex with Xanthine Anion: Dioxygen Pathways and a Portrait of the Enzyme Cavities from Molecular Dynamics Simulations in Water Solution.
    Pietra F
    Chem Biodivers; 2016 Jun; 13(6):798-806. PubMed ID: 27151738
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of quasi-stable water molecules near the Thr73-Lys13 catalytic diad of Bacillus sp. TB-90 urate oxidase by X-ray crystallography with controlled humidity.
    Hibi T; Itoh T
    J Biochem; 2021 Feb; 169(1):15-23. PubMed ID: 33002140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Production and characterization of recombinant perdeuterated cholesterol oxidase.
    Golden E; Attwood PV; Duff AP; Meilleur F; Vrielink A
    Anal Biochem; 2015 Sep; 485():102-8. PubMed ID: 26073659
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography.
    Wan Q; Bennett BC; Wilson MA; Kovalevsky A; Langan P; Howell EE; Dealwis C
    Proc Natl Acad Sci U S A; 2014 Dec; 111(51):18225-30. PubMed ID: 25453083
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined high-resolution neutron and X-ray analysis of inhibited elastase confirms the active-site oxyanion hole but rules against a low-barrier hydrogen bond.
    Tamada T; Kinoshita T; Kurihara K; Adachi M; Ohhara T; Imai K; Kuroki R; Tada T
    J Am Chem Soc; 2009 Aug; 131(31):11033-40. PubMed ID: 19603802
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oxygen pressurized X-ray crystallography: probing the dioxygen binding site in cofactorless urate oxidase and implications for its catalytic mechanism.
    Colloc'h N; Gabison L; Monard G; Altarsha M; Chiadmi M; Marassio G; Sopkova-de Oliveira Santos J; El Hajji M; Castro B; Abraini JH; Prangé T
    Biophys J; 2008 Sep; 95(5):2415-22. PubMed ID: 18375516
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of the protein drug urate oxidase-inhibitor complex at 2.05 A resolution.
    Colloc'h N; el Hajji M; Bachet B; L'Hermite G; Schiltz M; Prangé T; Castro B; Mornon JP
    Nat Struct Biol; 1997 Nov; 4(11):947-52. PubMed ID: 9360612
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.