112 related articles for article (PubMed ID: 33520367)
1. THZ1, a covalent CDK7 inhibitor, enhances gemcitabine-induced cytotoxicity via suppression of Bcl-2 in urothelial carcinoma.
Kuo KL; Lin WC; Liu SH; Hsu FS; Kuo Y; Liao SM; Yang SP; Wang ZH; Hsu CH; Huang KH
Am J Cancer Res; 2021; 11(1):171-180. PubMed ID: 33520367
[TBL] [Abstract][Full Text] [Related]
2. CDK7 inhibition by THZ1 suppresses cancer stemness in both chemonaïve and chemoresistant urothelial carcinoma via the hedgehog signaling pathway.
Chow PM; Chang YW; Kuo KL; Lin WC; Liu SH; Huang KH
Cancer Lett; 2021 Jun; 507():70-79. PubMed ID: 33741425
[TBL] [Abstract][Full Text] [Related]
3. Trifluoperazine, an Antipsychotic Drug, Effectively Reduces Drug Resistance in Cisplatin-Resistant Urothelial Carcinoma Cells via Suppressing Bcl-xL: An In Vitro and In Vivo Study.
Kuo KL; Liu SH; Lin WC; Hsu FS; Chow PM; Chang YW; Yang SP; Shi CS; Hsu CH; Liao SM; Chang HC; Huang KH
Int J Mol Sci; 2019 Jun; 20(13):. PubMed ID: 31262032
[TBL] [Abstract][Full Text] [Related]
4. The Deubiquitinating Enzyme Inhibitor PR-619 Enhances the Cytotoxicity of Cisplatin via the Suppression of Anti-Apoptotic Bcl-2 Protein: In Vitro and In Vivo Study.
Kuo KL; Liu SH; Lin WC; Chow PM; Chang YW; Yang SP; Shi CS; Hsu CH; Liao SM; Chang HC; Huang KH
Cells; 2019 Oct; 8(10):. PubMed ID: 31627336
[TBL] [Abstract][Full Text] [Related]
5. The covalent CDK7 inhibitor THZ1 enhances temsirolimus-induced cytotoxicity via autophagy suppression in human renal cell carcinoma.
Chow PM; Liu SH; Chang YW; Kuo KL; Lin WC; Huang KH
Cancer Lett; 2020 Feb; 471():27-37. PubMed ID: 31812697
[TBL] [Abstract][Full Text] [Related]
6. CDK7 inhibitor suppresses tumor progression through blocking the cell cycle at the G2/M phase and inhibiting transcriptional activity in cervical cancer.
Zhong S; Zhang Y; Yin X; Di W
Onco Targets Ther; 2019; 12():2137-2147. PubMed ID: 30962695
[TBL] [Abstract][Full Text] [Related]
7. CDK7 Inhibitor THZ1 Induces the Cell Apoptosis of B-Cell Acute Lymphocytic Leukemia by Perturbing Cellular Metabolism.
Abudureheman T; Xia J; Li MH; Zhou H; Zheng WW; Zhou N; Shi RY; Zhu JM; Yang LT; Chen L; Zheng L; Xue K; Qing K; Duan CW
Front Oncol; 2021; 11():663360. PubMed ID: 33889549
[TBL] [Abstract][Full Text] [Related]
8. MLN4924 Synergistically Enhances Cisplatin-induced Cytotoxicity via JNK and Bcl-xL Pathways in Human Urothelial Carcinoma.
Ho IL; Kuo KL; Liu SH; Chang HC; Hsieh JT; Wu JT; Chiang CK; Lin WC; Tsai YC; Chou CT; Hsu CH; Pu YS; Shi CS; Huang KH
Sci Rep; 2015 Nov; 5():16948. PubMed ID: 26592553
[TBL] [Abstract][Full Text] [Related]
9. PR-619, a General Inhibitor of Deubiquitylating Enzymes, Diminishes Cisplatin Resistance in Urothelial Carcinoma Cells through the Suppression of c-Myc: An In Vitro and In Vivo Study.
Hsu FS; Lin WC; Kuo KL; Chiu YL; Hsu CH; Liao SM; Dong JR; Liu SH; Chang SC; Yang SP; Chen YT; Chang RJ; Huang KH
Int J Mol Sci; 2021 Oct; 22(21):. PubMed ID: 34769137
[TBL] [Abstract][Full Text] [Related]
10. Nanomaterial-Facilitated Cyclin-Dependent Kinase 7 Inhibition Suppresses Gallbladder Cancer Progression via Targeting Transcriptional Addiction.
Huang CS; Xu QC; Dai C; Wang L; Tien YC; Li F; Su Q; Huang XT; Wu J; Zhao W; Yin XY
ACS Nano; 2021 Sep; 15(9):14744-14755. PubMed ID: 34405985
[TBL] [Abstract][Full Text] [Related]
11. Converged DNA Damage Response Renders Human Hepatocellular Carcinoma Sensitive to CDK7 Inhibition.
Xie G; Zhu A; Gu X
Cancers (Basel); 2022 Mar; 14(7):. PubMed ID: 35406486
[TBL] [Abstract][Full Text] [Related]
12. Covalent CDK7 Inhibitor THZ1 Inhibits Myogenic Differentiation.
Ma X; Kuang X; Xia Q; Huang Z; Fan Y; Ning J; Wen J; Zhang H; Yan J; Zhang Q; Shen H; Long C
J Cancer; 2018; 9(17):3149-3155. PubMed ID: 30210638
[TBL] [Abstract][Full Text] [Related]
13. Elevation of effective p53 expression sensitizes wild-type p53 breast cancer cells to CDK7 inhibitor THZ1.
Wang Y; Zhang Z; Mi X; Li M; Huang D; Song T; Qi X; Yang M
Cell Commun Signal; 2022 Sep; 20(1):96. PubMed ID: 36058938
[TBL] [Abstract][Full Text] [Related]
14. Co-overexpression of BRD4 and CDK7 promotes cell proliferation and predicts poor prognosis in HCC.
Li X; Zheng C; Liu Y; Sun H; Qian Y; Fan H
Heliyon; 2024 Jan; 10(2):e24389. PubMed ID: 38293462
[TBL] [Abstract][Full Text] [Related]
15. Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma.
Greenall SA; Lim YC; Mitchell CB; Ensbey KS; Stringer BW; Wilding AL; O'Neill GM; McDonald KL; Gough DJ; Day BW; Johns TG
Oncogenesis; 2017 May; 6(5):e336. PubMed ID: 28504693
[TBL] [Abstract][Full Text] [Related]
16. Targeting transcriptional kinase of CDK7 halts proliferation of multiple myeloma cells by modulating the function of canonical NF-kB pathway and cell cycle regulatory proteins.
Dutta RP; Kumar R; Tembhare PR; Bagal B; Swain RK; Hasan SK
Transl Oncol; 2023 Sep; 35():101729. PubMed ID: 37369156
[TBL] [Abstract][Full Text] [Related]
17. The UCHL5 inhibitor b-AP15 overcomes cisplatin resistance via suppression of cancer stemness in urothelial carcinoma.
Chow PM; Dong JR; Chang YW; Kuo KL; Lin WC; Liu SH; Huang KH
Mol Ther Oncolytics; 2022 Sep; 26():387-398. PubMed ID: 36090476
[TBL] [Abstract][Full Text] [Related]
18. Antitumor effects of a covalent cyclin-dependent kinase 7 inhibitor in colorectal cancer.
Wang J; Li Z; Mei H; Zhang D; Wu G; Zhang T; Lin Z
Anticancer Drugs; 2019 Jun; 30(5):466-474. PubMed ID: 30694816
[TBL] [Abstract][Full Text] [Related]
19. Cdk7 Is Required for Activity-Dependent Neuronal Gene Expression, Long-Lasting Synaptic Plasticity and Long-Term Memory.
He G; Yang X; Wang G; Qi J; Mao R; Wu Z; Zhou Z
Front Mol Neurosci; 2017; 10():365. PubMed ID: 29163040
[TBL] [Abstract][Full Text] [Related]
20. CDK7 inhibition is a novel therapeutic strategy against GBM both in vitro and in vivo.
Meng W; Wang J; Wang B; Liu F; Li M; Zhao Y; Zhang C; Li Q; Chen J; Zhang L; Tang Y; Ma J
Cancer Manag Res; 2018; 10():5747-5758. PubMed ID: 30532595
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]