202 related articles for article (PubMed ID: 33526511)
1. Targeting Pan-ETS Factors Inhibits Melanoma Progression.
Huang L; Zhai Y; La J; Lui JW; Moore SPG; Little EC; Xiao S; Haresi AJ; Brem C; Bhawan J; Lang D
Cancer Res; 2021 Apr; 81(8):2071-2085. PubMed ID: 33526511
[TBL] [Abstract][Full Text] [Related]
2. YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model.
Minas TZ; Han J; Javaheri T; Hong SH; Schlederer M; Saygideğer-Kont Y; Çelik H; Mueller KM; Temel I; Özdemirli M; Kovar H; Erkizan HV; Toretsky J; Kenner L; Moriggl R; Üren A
Oncotarget; 2015 Nov; 6(35):37678-94. PubMed ID: 26462019
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of the oncogenic fusion protein EWS-FLI1 causes G
Zöllner SK; Selvanathan SP; Graham GT; Commins RMT; Hong SH; Moseley E; Parks S; Haladyna JN; Erkizan HV; Dirksen U; Hogarty MD; Üren A; Toretsky JA
Sci Signal; 2017 Oct; 10(499):. PubMed ID: 28974650
[TBL] [Abstract][Full Text] [Related]
4. PAX3 and ETS1 synergistically activate MET expression in melanoma cells.
Kubic JD; Little EC; Lui JW; Iizuka T; Lang D
Oncogene; 2015 Sep; 34(38):4964-74. PubMed ID: 25531327
[TBL] [Abstract][Full Text] [Related]
5. Single enantiomer of YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1.
Barber-Rotenberg JS; Selvanathan SP; Kong Y; Erkizan HV; Snyder TM; Hong SP; Kobs CL; South NL; Summer S; Monroe PJ; Chruszcz M; Dobrev V; Tosso PN; Scher LJ; Minor W; Brown ML; Metallo SJ; Üren A; Toretsky JA
Oncotarget; 2012 Feb; 3(2):172-82. PubMed ID: 22383402
[TBL] [Abstract][Full Text] [Related]
6. Pharmacokinetic modeling optimizes inhibition of the 'undruggable' EWS-FLI1 transcription factor in Ewing Sarcoma.
Hong SH; Youbi SE; Hong SP; Kallakury B; Monroe P; Erkizan HV; Barber-Rotenberg JS; Houghton P; Üren A; Toretsky JA
Oncotarget; 2014 Jan; 5(2):338-50. PubMed ID: 24481407
[TBL] [Abstract][Full Text] [Related]
7. Development of Mithramycin Analogues with Increased Selectivity toward ETS Transcription Factor Expressing Cancers.
Mitra P; Eckenrode JM; Mandal A; Jha AK; Salem SM; Leggas M; Rohr J
J Med Chem; 2018 Sep; 61(17):8001-8016. PubMed ID: 30114371
[TBL] [Abstract][Full Text] [Related]
8. BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma.
Loganathan SN; Tang N; Fleming JT; Ma Y; Guo Y; Borinstein SC; Chiang C; Wang J
Oncotarget; 2016 Jul; 7(28):43504-43517. PubMed ID: 27259270
[TBL] [Abstract][Full Text] [Related]
9. FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on the Egr1 promoter serum response elements.
Watson DK; Robinson L; Hodge DR; Kola I; Papas TS; Seth A
Oncogene; 1997 Jan; 14(2):213-21. PubMed ID: 9010223
[TBL] [Abstract][Full Text] [Related]
10. Silencing FLI or targeting CD13/ANPEP lead to dephosphorylation of EPHA2, a mediator of BRAF inhibitor resistance, and induce growth arrest or apoptosis in melanoma cells.
Azimi A; Tuominen R; Costa Svedman F; Caramuta S; Pernemalm M; Frostvik Stolt M; Kanter L; Kharaziha P; Lehtiö J; Hertzman Johansson C; Höiom V; Hansson J; Egyhazi Brage S
Cell Death Dis; 2017 Aug; 8(8):e3029. PubMed ID: 29048432
[TBL] [Abstract][Full Text] [Related]
11. A small molecule inhibitor of ETV1, YK-4-279, prevents prostate cancer growth and metastasis in a mouse xenograft model.
Rahim S; Minas T; Hong SH; Justvig S; Çelik H; Kont YS; Han J; Kallarakal AT; Kong Y; Rudek MA; Brown ML; Kallakury B; Toretsky JA; Üren A
PLoS One; 2014; 9(12):e114260. PubMed ID: 25479232
[TBL] [Abstract][Full Text] [Related]
12. A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma.
Erkizan HV; Kong Y; Merchant M; Schlottmann S; Barber-Rotenberg JS; Yuan L; Abaan OD; Chou TH; Dakshanamurthy S; Brown ML; Uren A; Toretsky JA
Nat Med; 2009 Jul; 15(7):750-6. PubMed ID: 19584866
[TBL] [Abstract][Full Text] [Related]
13. Expression of c-Met proto-oncogene in metastatic macrophage x melanoma fusion hybrids: implication of its possible role in MSH-induced motility.
Chakraborty AK; Kolesnikova N; Sousa Jde F; Espreafico EM; Peronni KC; Pawelek J
Oncol Res; 2003; 14(3):163-74. PubMed ID: 14760865
[TBL] [Abstract][Full Text] [Related]
14. Cooperative DNA binding with AP-1 proteins is required for transformation by EWS-Ets fusion proteins.
Kim S; Denny CT; Wisdom R
Mol Cell Biol; 2006 Apr; 26(7):2467-78. PubMed ID: 16537893
[TBL] [Abstract][Full Text] [Related]
15. Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma.
Hensel T; Giorgi C; Schmidt O; Calzada-Wack J; Neff F; Buch T; Niggli FK; Schäfer BW; Burdach S; Richter GH
Oncotarget; 2016 Jan; 7(2):1451-63. PubMed ID: 26623725
[TBL] [Abstract][Full Text] [Related]
16. YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion.
Rahim S; Beauchamp EM; Kong Y; Brown ML; Toretsky JA; Üren A
PLoS One; 2011 Apr; 6(4):e19343. PubMed ID: 21559405
[TBL] [Abstract][Full Text] [Related]
17. EWS/ETS-Driven Ewing Sarcoma Requires BET Bromodomain Proteins.
Gollavilli PN; Pawar A; Wilder-Romans K; Natesan R; Engelke CG; Dommeti VL; Krishnamurthy PM; Nallasivam A; Apel IJ; Xu T; Qin ZS; Feng FY; Asangani IA
Cancer Res; 2018 Aug; 78(16):4760-4773. PubMed ID: 29898995
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and structure-activity relationship studies of small molecule disruptors of EWS-FLI1 interactions in Ewing's sarcoma.
Tosso PN; Kong Y; Scher L; Cummins R; Schneider J; Rahim S; Holman KT; Toretsky J; Wang K; Üren A; Brown ML
J Med Chem; 2014 Dec; 57(24):10290-303. PubMed ID: 25432018
[TBL] [Abstract][Full Text] [Related]
19. Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.
Watanabe G; Nishimori H; Irifune H; Sasaki Y; Ishida S; Zembutsu H; Tanaka T; Kawaguchi S; Wada T; Hata J; Kusakabe M; Yoshida K; Nakamura Y; Tokino T
Genes Chromosomes Cancer; 2003 Mar; 36(3):224-32. PubMed ID: 12557222
[TBL] [Abstract][Full Text] [Related]
20. Blocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy.
Kovar H
Expert Opin Ther Targets; 2014 Nov; 18(11):1315-28. PubMed ID: 25162919
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
