BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 33527351)

  • 1. Bayesian dose regimen assessment in early phase oncology incorporating pharmacokinetics and pharmacodynamics.
    Gerard E; Zohar S; Thai HT; Lorenzato C; Riviere MK; Ursino M
    Biometrics; 2022 Mar; 78(1):300-312. PubMed ID: 33527351
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bayesian modeling of a bivariate toxicity outcome for early phase oncology trials evaluating dose regimens.
    Gerard E; Zohar S; Lorenzato C; Ursino M; Riviere MK
    Stat Med; 2021 Oct; 40(23):5096-5114. PubMed ID: 34259343
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An extended Bayesian semi-mechanistic dose-finding design for phase I oncology trials using pharmacokinetic and pharmacodynamic information.
    Yang C; Li Y
    Stat Med; 2024 Feb; 43(4):689-705. PubMed ID: 38110304
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An adaptive multi-stage phase I dose-finding design incorporating continuous efficacy and toxicity data from multiple treatment cycles.
    Du Y; Yin J; Sargent DJ; Mandrekar SJ
    J Biopharm Stat; 2019; 29(2):271-286. PubMed ID: 30403559
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phase I dose-escalation oncology trials with sequential multiple schedules.
    Günhan BK; Weber S; Seroutou A; Friede T
    BMC Med Res Methodol; 2021 Apr; 21(1):69. PubMed ID: 33853539
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Optimal phase I dose-escalation trial designs in oncology--a simulation study.
    Gerke O; Siedentop H
    Stat Med; 2008 Nov; 27(26):5329-44. PubMed ID: 17849502
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Bayesian adaptive design for cancer phase I trials using a flexible range of doses.
    Tighiouart M; Cook-Wiens G; Rogatko A
    J Biopharm Stat; 2018; 28(3):562-574. PubMed ID: 28858566
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Adaptive Bayesian phase I clinical trial designs for estimating the maximum tolerated doses for two drugs while fully utilizing all toxicity information.
    Zhang Y; Kutner M; Chen Z
    Biom J; 2021 Oct; 63(7):1476-1492. PubMed ID: 33969525
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Bayesian adaptive Phase I-II clinical trial for evaluating efficacy and toxicity with delayed outcomes.
    Koopmeiners JS; Modiano J
    Clin Trials; 2014 Feb; 11(1):38-48. PubMed ID: 24082004
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dose finding with drug combinations in cancer phase I clinical trials using conditional escalation with overdose control.
    Tighiouart M; Piantadosi S; Rogatko A
    Stat Med; 2014 Sep; 33(22):3815-29. PubMed ID: 24825779
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DICE: A Bayesian model for early dose finding in phase I trials with multiple treatment courses.
    Ursino M; Biard L; Chevret S
    Biom J; 2022 Dec; 64(8):1486-1497. PubMed ID: 34729815
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Repeated measures dose-finding design with time-trend detection in the presence of correlated toxicity data.
    Yin J; Paoletti X; Sargent DJ; Mandrekar SJ
    Clin Trials; 2017 Dec; 14(6):611-620. PubMed ID: 28764555
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Escalation with overdose control using all toxicities and time to event toxicity data in cancer Phase I clinical trials.
    Chen Z; Cui Y; Owonikoko TK; Wang Z; Li Z; Luo R; Kutner M; Khuri FR; Kowalski J
    Contemp Clin Trials; 2014 Mar; 37(2):322-32. PubMed ID: 24530487
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Assessment of various continual reassessment method models for dose-escalation phase 1 oncology clinical trials: using real clinical data and simulation studies.
    James GD; Symeonides S; Marshall J; Young J; Clack G
    BMC Cancer; 2021 Jan; 21(1):7. PubMed ID: 33402104
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bayesian dose-finding phase I trial design incorporating pharmacokinetic assessment in the field of oncology.
    Takeda K; Komatsu K; Morita S
    Pharm Stat; 2018 Nov; 17(6):725-733. PubMed ID: 30066356
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Designing phase I oncology dose escalation using dose-exposure-toxicity models as a complementary approach to model-based dose-toxicity models.
    Pantoja K; Lanke S; Munafo A; Victor A; Habermehl C; Schueler A; Venkatakrishnan K; Girard P; Goteti K
    CPT Pharmacometrics Syst Pharmacol; 2022 Oct; 11(10):1371-1381. PubMed ID: 35852048
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Introduction of Oncology Dose-Finding Trial Designs].
    Takeda K
    Gan To Kagaku Ryoho; 2022 Apr; 49(4):365-370. PubMed ID: 35444116
    [TBL] [Abstract][Full Text] [Related]  

  • 18. dfpk: An R-package for Bayesian dose-finding designs using pharmacokinetics (PK) for phase I clinical trials.
    Toumazi A; Comets E; Alberti C; Friede T; Lentz F; Stallard N; Zohar S; Ursino M
    Comput Methods Programs Biomed; 2018 Apr; 157():163-177. PubMed ID: 29477425
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Challenges of phase 1 clinical trials evaluating immune checkpoint-targeted antibodies.
    Postel-Vinay S; Aspeslagh S; Lanoy E; Robert C; Soria JC; Marabelle A
    Ann Oncol; 2016 Feb; 27(2):214-24. PubMed ID: 26578728
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Competing designs for drug combination in phase I dose-finding clinical trials.
    Riviere MK; Dubois F; Zohar S
    Stat Med; 2015 Jan; 34(1):1-12. PubMed ID: 24464821
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.