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3. Cooperative targeting of melanoma heterogeneity with an AXL antibody-drug conjugate and BRAF/MEK inhibitors. Boshuizen J; Koopman LA; Krijgsman O; Shahrabi A; van den Heuvel EG; Ligtenberg MA; Vredevoogd DW; Kemper K; Kuilman T; Song JY; Pencheva N; Mortensen JT; Foppen MG; Rozeman EA; Blank CU; Janmaat ML; Satijn D; Breij ECW; Peeper DS; Parren PWHI Nat Med; 2018 Feb; 24(2):203-212. PubMed ID: 29334371 [TBL] [Abstract][Full Text] [Related]
4. Dual Inhibition of MEK and AXL Targets Tumor Cell Heterogeneity and Prevents Resistant Outgrowth Mediated by the Epithelial-to-Mesenchymal Transition in NSCLC. Konen JM; Rodriguez BL; Padhye A; Ochieng JK; Gibson L; Diao L; Fowlkes NW; Fradette JJ; Peng DH; Cardnell RJ; Kovacs JJ; Wang J; Byers LA; Gibbons DL Cancer Res; 2021 Mar; 81(5):1398-1412. PubMed ID: 33402388 [TBL] [Abstract][Full Text] [Related]
5. Single-Cell Proteomic Profiling Identifies Combined AXL and JAK1 Inhibition as a Novel Therapeutic Strategy for Lung Cancer. Taverna JA; Hung CN; DeArmond DT; Chen M; Lin CL; Osmulski PA; Gaczynska ME; Wang CM; Lucio ND; Chou CW; Chen CL; Nazarullah A; Lampkin SR; Qiu L; Bearss DJ; Warner S; Whatcott CJ; Mouritsen L; Wade M; Weitman S; Mesa RA; Kirma NB; Chao WT; Huang TH Cancer Res; 2020 Apr; 80(7):1551-1563. PubMed ID: 31992541 [TBL] [Abstract][Full Text] [Related]
6. Axl and Mertk Receptors Cooperate to Promote Breast Cancer Progression by Combined Oncogenic Signaling and Evasion of Host Antitumor Immunity. Davra V; Kumar S; Geng K; Calianese D; Mehta D; Gadiyar V; Kasikara C; Lahey KC; Chang YJ; Wichroski M; Gao C; De Lorenzo MS; Kotenko SV; Bergsbaken T; Mishra PK; Gause WC; Quigley M; Spires TE; Birge RB Cancer Res; 2021 Feb; 81(3):698-712. PubMed ID: 33239426 [TBL] [Abstract][Full Text] [Related]
7. Targeting AXL and the DNA Damage Response Pathway as a Novel Therapeutic Strategy in Melanoma. Flem-Karlsen K; McFadden E; Omar N; Haugen MH; Øy GF; Ryder T; Gullestad HP; Hermann R; Mælandsmo GM; Flørenes VA Mol Cancer Ther; 2020 Mar; 19(3):895-905. PubMed ID: 31871265 [TBL] [Abstract][Full Text] [Related]
8. Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels. Goyette MA; Elkholi IE; Apcher C; Kuasne H; Rothlin CV; Muller WJ; Richard DE; Park M; Gratton JP; Côté JF Proc Natl Acad Sci U S A; 2021 Jul; 118(29):. PubMed ID: 34266948 [TBL] [Abstract][Full Text] [Related]
9. In situ immunogenic clearance induced by a combination of photodynamic therapy and rho-kinase inhibition sensitizes immune checkpoint blockade response to elicit systemic antitumor immunity against intraocular melanoma and its metastasis. Kim S; Kim SA; Nam GH; Hong Y; Kim GB; Choi Y; Lee S; Cho Y; Kwon M; Jeong C; Kim S; Kim IS J Immunother Cancer; 2021 Jan; 9(1):. PubMed ID: 33479026 [TBL] [Abstract][Full Text] [Related]
10. Enapotamab Vedotin, an AXL-Specific Antibody-Drug Conjugate, Demonstrates Antitumor Efficacy in Patient-Derived Xenograft Models of Soft Tissue Sarcoma. Van Renterghem B; Wozniak A; Castro PG; Franken P; Pencheva N; Sciot R; Schöffski P Int J Mol Sci; 2022 Jul; 23(14):. PubMed ID: 35886842 [TBL] [Abstract][Full Text] [Related]
11. Broad RTK-targeted therapy overcomes molecular heterogeneity-driven resistance to cetuximab via vectored immunoprophylaxis in colorectal cancer. Hu S; Dai H; Li T; Tang Y; Fu W; Yuan Q; Wang F; Lv G; Lv Y; Fan X; Zhang S; Jin R; Shen Y; Lin F; Ye X; Ding M; Yang Y; Lei C Cancer Lett; 2016 Nov; 382(1):32-43. PubMed ID: 27569653 [TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and validation of Axl-targeted monoclonal antibody probe for microPET imaging in human lung cancer xenograft. Liu S; Li D; Guo J; Canale N; Li X; Liu R; Krasnoperov V; Gill PS; Conti PS; Shan H; Li Z Mol Pharm; 2014 Nov; 11(11):3974-9. PubMed ID: 24978094 [TBL] [Abstract][Full Text] [Related]
13. AXL Targeting Overcomes Human Lung Cancer Cell Resistance to NK- and CTL-Mediated Cytotoxicity. Terry S; Abdou A; Engelsen AST; Buart S; Dessen P; Corgnac S; Collares D; Meurice G; Gausdal G; Baud V; Saintigny P; Lorens JB; Thiery JP; Mami-Chouaib F; Chouaib S Cancer Immunol Res; 2019 Nov; 7(11):1789-1802. PubMed ID: 31488404 [TBL] [Abstract][Full Text] [Related]
14. Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions. Kato Y; Ninomiya K; Ohashi K; Tomida S; Makimoto G; Watanabe H; Kudo K; Matsumoto S; Umemura S; Goto K; Ichihara E; Ninomiya T; Kubo T; Sato A; Hotta K; Tabata M; Toyooka S; Maeda Y; Kiura K Cancer Sci; 2018 Oct; 109(10):3149-3158. PubMed ID: 30053332 [TBL] [Abstract][Full Text] [Related]
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16. ONO-7475, a Novel AXL Inhibitor, Suppresses the Adaptive Resistance to Initial EGFR-TKI Treatment in Okura N; Nishioka N; Yamada T; Taniguchi H; Tanimura K; Katayama Y; Yoshimura A; Watanabe S; Kikuchi T; Shiotsu S; Kitazaki T; Nishiyama A; Iwasaku M; Kaneko Y; Uchino J; Uehara H; Horinaka M; Sakai T; Tanaka K; Kozaki R; Yano S; Takayama K Clin Cancer Res; 2020 May; 26(9):2244-2256. PubMed ID: 31953310 [TBL] [Abstract][Full Text] [Related]
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