These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Mutated SPOP E3 Ligase Promotes 17βHSD4 Protein Degradation to Drive Androgenesis and Prostate Cancer Progression. Shi L; Yan Y; He Y; Yan B; Pan Y; Orme JJ; Zhang J; Xu W; Pang J; Huang H Cancer Res; 2021 Jul; 81(13):3593-3606. PubMed ID: 33762355 [TBL] [Abstract][Full Text] [Related]
6. Destruction of full-length androgen receptor by wild-type SPOP, but not prostate-cancer-associated mutants. An J; Wang C; Deng Y; Yu L; Huang H Cell Rep; 2014 Feb; 6(4):657-69. PubMed ID: 24508459 [TBL] [Abstract][Full Text] [Related]
7. CHD1 and SPOP synergistically protect prostate epithelial cells from DNA damage. Zhu Y; Wen J; Huang G; Mittlesteadt J; Wen X; Lu X Prostate; 2021 Jan; 81(1):81-88. PubMed ID: 33022763 [TBL] [Abstract][Full Text] [Related]
8. Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover. Geng C; He B; Xu L; Barbieri CE; Eedunuri VK; Chew SA; Zimmermann M; Bond R; Shou J; Li C; Blattner M; Lonard DM; Demichelis F; Coarfa C; Rubin MA; Zhou P; O'Malley BW; Mitsiades N Proc Natl Acad Sci U S A; 2013 Apr; 110(17):6997-7002. PubMed ID: 23559371 [TBL] [Abstract][Full Text] [Related]
9. SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein. Geng C; Kaochar S; Li M; Rajapakshe K; Fiskus W; Dong J; Foley C; Dong B; Zhang L; Kwon OJ; Shah SS; Bolaki M; Xin L; Ittmann M; O'Malley BW; Coarfa C; Mitsiades N Oncogene; 2017 Aug; 36(33):4767-4777. PubMed ID: 28414305 [TBL] [Abstract][Full Text] [Related]
10. Clinical and genomic features of SPOP-mutant prostate cancer. Nakazawa M; Fang M; H Marshall C; Lotan TL; Isaacsson Velho P; Antonarakis ES Prostate; 2022 Feb; 82(2):260-268. PubMed ID: 34783071 [TBL] [Abstract][Full Text] [Related]
11. Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4. Dai X; Gan W; Li X; Wang S; Zhang W; Huang L; Liu S; Zhong Q; Guo J; Zhang J; Chen T; Shimizu K; Beca F; Blattner M; Vasudevan D; Buckley DL; Qi J; Buser L; Liu P; Inuzuka H; Beck AH; Wang L; Wild PJ; Garraway LA; Rubin MA; Barbieri CE; Wong KK; Muthuswamy SK; Huang J; Chen Y; Bradner JE; Wei W Nat Med; 2017 Sep; 23(9):1063-1071. PubMed ID: 28805820 [TBL] [Abstract][Full Text] [Related]
12. Truncated ERG Oncoproteins from TMPRSS2-ERG Fusions Are Resistant to SPOP-Mediated Proteasome Degradation. An J; Ren S; Murphy SJ; Dalangood S; Chang C; Pang X; Cui Y; Wang L; Pan Y; Zhang X; Zhu Y; Wang C; Halling GC; Cheng L; Sukov WR; Karnes RJ; Vasmatzis G; Zhang Q; Zhang J; Cheville JC; Yan J; Sun Y; Huang H Mol Cell; 2015 Sep; 59(6):904-16. PubMed ID: 26344096 [TBL] [Abstract][Full Text] [Related]
13. ERG-Mediated Coregulator Complex Formation Maintains Androgen Receptor Signaling in Prostate Cancer. Shah N; Kesten N; Font-Tello A; Chang MEK; Vadhi R; Lim K; Flory MR; Cejas P; Mohammed H; Long HW; Brown M Cancer Res; 2020 Nov; 80(21):4612-4619. PubMed ID: 32934023 [TBL] [Abstract][Full Text] [Related]
14. Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors. Janouskova H; El Tekle G; Bellini E; Udeshi ND; Rinaldi A; Ulbricht A; Bernasocchi T; Civenni G; Losa M; Svinkina T; Bielski CM; Kryukov GV; Cascione L; Napoli S; Enchev RI; Mutch DG; Carney ME; Berchuck A; Winterhoff BJN; Broaddus RR; Schraml P; Moch H; Bertoni F; Catapano CV; Peter M; Carr SA; Garraway LA; Wild PJ; Theurillat JP Nat Med; 2017 Sep; 23(9):1046-1054. PubMed ID: 28805821 [TBL] [Abstract][Full Text] [Related]
15. SPOP and CHD1 alterations in prostate cancer: Relationship with PTEN loss, tumor grade, perineural infiltration, and PSA recurrence. Hernández-Llodrà S; Segalés L; Juanpere N; Marta Lorenzo T; Salido M; Nonell L; David López T; Rodríguez-Vida A; Bellmunt J; Fumadó L; Cecchini L; Lloreta-Trull J Prostate; 2021 Dec; 81(16):1267-1277. PubMed ID: 34533858 [TBL] [Abstract][Full Text] [Related]
16. SPOP-mutant prostate cancer: Translating fundamental biology into patient care. Bernasocchi T; Theurillat JP Cancer Lett; 2022 Mar; 529():11-18. PubMed ID: 34974131 [TBL] [Abstract][Full Text] [Related]
17. GLI3 Is Stabilized by SPOP Mutations and Promotes Castration Resistance via Functional Cooperation with Androgen Receptor in Prostate Cancer. Burleson M; Deng JJ; Qin T; Duong TM; Yan Y; Gu X; Das D; Easley A; Liss MA; Yew PR; Bedolla R; Kumar AP; Huang TH; Zou Y; Chen Y; Chen CL; Huang H; Sun LZ; Boyer TG Mol Cancer Res; 2022 Jan; 20(1):62-76. PubMed ID: 34610962 [TBL] [Abstract][Full Text] [Related]
18. Dual inhibition of AKT-mTOR and AR signaling by targeting HDAC3 in Yan Y; An J; Yang Y; Wu D; Bai Y; Cao W; Ma L; Chen J; Yu Z; He Y; Jin X; Pan Y; Ma T; Wang S; Hou X; Weroha SJ; Karnes RJ; Zhang J; Westendorf JJ; Wang L; Chen Y; Xu W; Zhu R; Wang D; Huang H EMBO Mol Med; 2018 Apr; 10(4):. PubMed ID: 29523594 [TBL] [Abstract][Full Text] [Related]
19. SPOP promotes CDCA5 degradation to regulate prostate cancer progression via the AKT pathway. Luo Z; Wang J; Zhu Y; Sun X; He C; Cai M; Ma J; Wang Y; Han S Neoplasia; 2021 Oct; 23(10):1037-1047. PubMed ID: 34509929 [TBL] [Abstract][Full Text] [Related]
20. Phosphorylation-dependent regulation of SPOP by LIMK2 promotes castration-resistant prostate cancer. Nikhil K; Haymour HS; Kamra M; Shah K Br J Cancer; 2021 Mar; 124(5):995-1008. PubMed ID: 33311589 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]