BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 33531658)

  • 1. Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51.
    Manic G; Musella M; Corradi F; Sistigu A; Vitale S; Soliman Abdel Rehim S; Mattiello L; Malacaria E; Galassi C; Signore M; Pallocca M; Scalera S; Goeman F; De Nicola F; Guarracino A; Pennisi R; Antonangeli F; Sperati F; Baiocchi M; Biffoni M; Fanciulli M; Maugeri-Saccà M; Franchitto A; Pichierri P; De Maria R; Vitale I
    Cell Death Differ; 2021 Jul; 28(7):2060-2082. PubMed ID: 33531658
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CHK1-targeted therapy to deplete DNA replication-stressed, p53-deficient, hyperdiploid colorectal cancer stem cells.
    Manic G; Signore M; Sistigu A; Russo G; Corradi F; Siteni S; Musella M; Vitale S; De Angelis ML; Pallocca M; Amoreo CA; Sperati F; Di Franco S; Barresi S; Policicchio E; De Luca G; De Nicola F; Mottolese M; Zeuner A; Fanciulli M; Stassi G; Maugeri-Saccà M; Baiocchi M; Tartaglia M; Vitale I; De Maria R
    Gut; 2018 May; 67(5):903-917. PubMed ID: 28389531
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Targeting of MRE11 or RAD51 Sensitizes Colorectal Cancer Stem Cells to CHK1 Inhibition.
    Mattiello L; Soliman Abdel Rehim S; Musella M; Sistigu A; Guarracino A; Vitale S; Corradi F; Galassi C; Sperati F; Manic G; De Maria R; Vitale I
    Cancers (Basel); 2021 Apr; 13(8):. PubMed ID: 33921638
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Replication stress response in cancer stem cells as a target for chemotherapy.
    Manic G; Sistigu A; Corradi F; Musella M; De Maria R; Vitale I
    Semin Cancer Biol; 2018 Dec; 53():31-41. PubMed ID: 30081229
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MRE11 deficiency increases sensitivity to poly(ADP-ribose) polymerase inhibition in microsatellite unstable colorectal cancers.
    Vilar E; Bartnik CM; Stenzel SL; Raskin L; Ahn J; Moreno V; Mukherjee B; Iniesta MD; Morgan MA; Rennert G; Gruber SB
    Cancer Res; 2011 Apr; 71(7):2632-42. PubMed ID: 21300766
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RAD51 Mediates Resistance of Cancer Stem Cells to PARP Inhibition in Triple-Negative Breast Cancer.
    Liu Y; Burness ML; Martin-Trevino R; Guy J; Bai S; Harouaka R; Brooks MD; Shang L; Fox A; Luther TK; Davis A; Baker TL; Colacino J; Clouthier SG; Shao ZM; Wicha MS; Liu S
    Clin Cancer Res; 2017 Jan; 23(2):514-522. PubMed ID: 28034904
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting replication stress to tackle cancer stem cells.
    Galluzzi L
    Cell Death Dis; 2021 Mar; 12(4):315. PubMed ID: 33762581
    [No Abstract]   [Full Text] [Related]  

  • 8. PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastoma.
    Colicchia V; Petroni M; Guarguaglini G; Sardina F; Sahún-Roncero M; Carbonari M; Ricci B; Heil C; Capalbo C; Belardinilli F; Coppa A; Peruzzi G; Screpanti I; Lavia P; Gulino A; Giannini G
    Oncogene; 2017 Aug; 36(33):4682-4691. PubMed ID: 28394338
    [TBL] [Abstract][Full Text] [Related]  

  • 9. UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response.
    Signore M; Buccarelli M; Pilozzi E; De Luca G; Cappellari M; Fanciulli M; Goeman F; Melucci E; Biffoni M; Ricci-Vitiani L
    Oncotarget; 2016 Jul; 7(28):44113-44128. PubMed ID: 27286453
    [TBL] [Abstract][Full Text] [Related]  

  • 10. RADX Modulates RAD51 Activity to Control Replication Fork Protection.
    Bhat KP; Krishnamoorthy A; Dungrawala H; Garcin EB; Modesti M; Cortez D
    Cell Rep; 2018 Jul; 24(3):538-545. PubMed ID: 30021152
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments.
    Kolinjivadi AM; Sannino V; De Antoni A; Zadorozhny K; Kilkenny M; Técher H; Baldi G; Shen R; Ciccia A; Pellegrini L; Krejci L; Costanzo V
    Mol Cell; 2017 Sep; 67(5):867-881.e7. PubMed ID: 28757209
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enhanced dependency of KRAS-mutant colorectal cancer cells on RAD51-dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae.
    Kalimutho M; Bain AL; Mukherjee B; Nag P; Nanayakkara DM; Harten SK; Harris JL; Subramanian GN; Sinha D; Shirasawa S; Srihari S; Burma S; Khanna KK
    Mol Oncol; 2017 May; 11(5):470-490. PubMed ID: 28173629
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stalled replication forks within heterochromatin require ATRX for protection.
    Huh MS; Ivanochko D; Hashem LE; Curtin M; Delorme M; Goodall E; Yan K; Picketts DJ
    Cell Death Dis; 2016 May; 7(5):e2220. PubMed ID: 27171262
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitotic regulators TPX2 and Aurora A protect DNA forks during replication stress by counteracting 53BP1 function.
    Byrum AK; Carvajal-Maldonado D; Mudge MC; Valle-Garcia D; Majid MC; Patel R; Sowa ME; Gygi SP; Harper JW; Shi Y; Vindigni A; Mosammaparast N
    J Cell Biol; 2019 Feb; 218(2):422-432. PubMed ID: 30602538
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The RECQL helicase prevents replication fork collapse during replication stress.
    Benedict B; van Bueren MA; van Gemert FP; Lieftink C; Guerrero Llobet S; van Vugt MA; Beijersbergen RL; Te Riele H
    Life Sci Alliance; 2020 Oct; 3(10):. PubMed ID: 32820027
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A Short BRCA2-Derived Cell-Penetrating Peptide Targets RAD51 Function and Confers Hypersensitivity toward PARP Inhibition.
    Trenner A; Godau J; Sartori AA
    Mol Cancer Ther; 2018 Jul; 17(7):1392-1404. PubMed ID: 29654063
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice.
    Lombardo Y; Scopelliti A; Cammareri P; Todaro M; Iovino F; Ricci-Vitiani L; Gulotta G; Dieli F; de Maria R; Stassi G
    Gastroenterology; 2011 Jan; 140(1):297-309. PubMed ID: 20951698
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks.
    Kim TM; Son MY; Dodds S; Hu L; Hasty P
    Mutat Res; 2014; 766-767():66-72. PubMed ID: 25847274
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of DNA double-strand break repair proteins predicts the response and prognosis of colorectal cancer patients undergoing oxaliplatin-based chemotherapy.
    Ihara K; Yamaguchi S; Ueno N; Tani Y; Shida Y; Ogata H; Domeki Y; Okamoto K; Nakajima M; Sasaki K; Tsuchioka T; Mitomi H; Kato H
    Oncol Rep; 2016 Mar; 35(3):1349-55. PubMed ID: 26676960
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The oncoprotein DEK affects the outcome of PARP1/2 inhibition during mild replication stress.
    Ganz M; Vogel C; Czada C; Jörke V; Gwosch EC; Kleiner R; Pierzynska-Mach A; Zanacchi FC; Diaspro A; Kappes F; Bürkle A; Ferrando-May E
    PLoS One; 2019; 14(8):e0213130. PubMed ID: 31408463
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.