212 related articles for article (PubMed ID: 33548273)
1. The tertiary oxime monoisonitrosoacetone penetrates the brain, reactivates inhibited acetylcholinesterase, and reduces mortality and morbidity following lethal sarin intoxication in guinea pigs.
Shih TM; Oyler BL; Capacio BR; Koplovitz I
Toxicol Appl Pharmacol; 2021 Mar; 415():115443. PubMed ID: 33548273
[TBL] [Abstract][Full Text] [Related]
2. Reactivation of brain acetylcholinesterase by monoisonitrosoacetone increases the therapeutic efficacy against nerve agents in guinea pigs.
Skovira JW; O'Donnell JC; Koplovitz I; Kan RK; McDonough JH; Shih TM
Chem Biol Interact; 2010 Sep; 187(1-3):318-24. PubMed ID: 20230808
[TBL] [Abstract][Full Text] [Related]
3. Treatment with tertiary oximes prevents seizures and improves survival following sarin intoxication.
Shih TM; Skovira JW; O'Donnell JC; McDonough JH
J Mol Neurosci; 2010 Jan; 40(1-2):63-9. PubMed ID: 19680820
[TBL] [Abstract][Full Text] [Related]
4. Reactivation of organophosphate-inhibited human acetylcholinesterase by isonitrosoacetone (MINA): a kinetic analysis.
Worek F; Thiermann H
Chem Biol Interact; 2011 Nov; 194(2-3):91-6. PubMed ID: 21930118
[TBL] [Abstract][Full Text] [Related]
5. Reactivation of sarin-inhibited pig brain acetylcholinesterase using oxime antidotes.
Kuca K; Jun D
J Med Toxicol; 2006 Dec; 2(4):141-6. PubMed ID: 18072133
[TBL] [Abstract][Full Text] [Related]
6. Evaluation of nine oximes on in vivo reactivation of blood, brain, and tissue cholinesterase activity inhibited by organophosphorus nerve agents at lethal dose.
Shih TM; Skovira JW; O'Donnell JC; McDonough JH
Toxicol Mech Methods; 2009 Sep; 19(6-7):386-400. PubMed ID: 19778239
[TBL] [Abstract][Full Text] [Related]
7. Pro-2-PAM therapy for central and peripheral cholinesterases.
Demar JC; Clarkson ED; Ratcliffe RH; Campbell AJ; Thangavelu SG; Herdman CA; Leader H; Schulz SM; Marek E; Medynets MA; Ku TC; Evans SA; Khan FA; Owens RR; Nambiar MP; Gordon RK
Chem Biol Interact; 2010 Sep; 187(1-3):191-8. PubMed ID: 20156430
[TBL] [Abstract][Full Text] [Related]
8. A comprehensive evaluation of the efficacy of leading oxime therapies in guinea pigs exposed to organophosphorus chemical warfare agents or pesticides.
Wilhelm CM; Snider TH; Babin MC; Jett DA; Platoff GE; Yeung DT
Toxicol Appl Pharmacol; 2014 Dec; 281(3):254-65. PubMed ID: 25448441
[TBL] [Abstract][Full Text] [Related]
9. Reduction by pyridostigmine pretreatment of the efficacy of atropine and 2-PAM treatment of sarin and VX poisoning in rodents.
Koplovitz I; Harris LW; Anderson DR; Lennox WJ; Stewart JR
Fundam Appl Toxicol; 1992 Jan; 18(1):102-6. PubMed ID: 1601200
[TBL] [Abstract][Full Text] [Related]
10. In vivo reactivation by oximes of inhibited blood, brain and peripheral tissue cholinesterase activity following exposure to nerve agents in guinea pigs.
Shih TM; Skovira JW; O'Donnell JC; McDonough JH
Chem Biol Interact; 2010 Sep; 187(1-3):207-14. PubMed ID: 20223229
[TBL] [Abstract][Full Text] [Related]
11. Effects of K074 and pralidoxime on antioxidant and acetylcholinesterase response in malathion-poisoned mice.
dos Santos AA; dos Santos DB; Ribeiro RP; Colle D; Peres KC; Hermes J; Barbosa AM; Dafré AL; de Bem AF; Kuca K; Farina M
Neurotoxicology; 2011 Dec; 32(6):888-95. PubMed ID: 21723318
[TBL] [Abstract][Full Text] [Related]
12. In silico and in vitro evaluation of two novel oximes (K378 and K727) in comparison to K-27 and pralidoxime against paraoxon-ethyl intoxication.
Arshad M; Fatmi MQ; Musilek K; Hussain A; Kuca K; Petroianu G; Kalasz H; Nurulain SM
Toxicol Mech Methods; 2018 Jan; 28(1):62-68. PubMed ID: 28722512
[TBL] [Abstract][Full Text] [Related]
13. Probing the activity of a non-oxime reactivator for acetylcholinesterase inhibited by organophosphorus nerve agents.
Cadieux CL; Wang H; Zhang Y; Koenig JA; Shih TM; McDonough J; Koh J; Cerasoli D
Chem Biol Interact; 2016 Nov; 259(Pt B):133-141. PubMed ID: 27062893
[TBL] [Abstract][Full Text] [Related]
14. Efficacy of novel phenoxyalkyl pyridinium oximes as brain-penetrating reactivators of cholinesterase inhibited by surrogates of sarin and VX.
Chambers JE; Chambers HW; Funck KE; Meek EC; Pringle RB; Ross MK
Chem Biol Interact; 2016 Nov; 259(Pt B):154-159. PubMed ID: 27387540
[TBL] [Abstract][Full Text] [Related]
15. Effects of 4-pyridine aldoxime on nerve agent-inhibited acetylcholinesterase activity in guinea pigs.
Shih TM; Skovira JW; McDonough JH
Arch Toxicol; 2009 Dec; 83(12):1083-9. PubMed ID: 19763542
[TBL] [Abstract][Full Text] [Related]
16. Toxicity and median effective doses of oxime therapies against percutaneous organophosphorus pesticide and nerve agent challenges in the Hartley guinea pig.
Snider TH; Babin MC; Jett DA; Platoff GE; Yeung DT
J Toxicol Sci; 2016; 41(4):511-21. PubMed ID: 27432237
[TBL] [Abstract][Full Text] [Related]
17. Novel bifunctional hybrid small molecule scavengers for mitigating nerve agents toxicity.
Amitai G; Gez R; Raveh L; Bar-Ner N; Grauer E; Chapman S
Chem Biol Interact; 2016 Nov; 259(Pt B):187-204. PubMed ID: 27129421
[TBL] [Abstract][Full Text] [Related]
18. Potency of novel oximes to reactivate sarin inhibited human cholinesterases.
Jun D; Kuca K; Picha J; Koleckar V; Marek J
Drug Chem Toxicol; 2008; 31(1):1-9. PubMed ID: 18161504
[TBL] [Abstract][Full Text] [Related]
19. Oximes and atropine in sarin poisoning.
ASKEW BM
Br J Pharmacol Chemother; 1957 Sep; 12(3):340-3. PubMed ID: 13460241
[TBL] [Abstract][Full Text] [Related]
20. In vivo oxime administration does not influence Ellman acetylcholinesterase assay results.
Guarisco JA; O'Donnell JC; Skovira JW; McDonough JH; Shih TM
Toxicol Mech Methods; 2009 Sep; 19(6-7):379-85. PubMed ID: 19778238
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
