488 related articles for article (PubMed ID: 33550186)
1. A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents.
Romagnoli R; Oliva P; Salvador MK; Manfredini S; Padroni C; Brancale A; Ferla S; Hamel E; Ronca R; Maccarinelli F; Rruga F; Mariotto E; Viola G; Bortolozzi R
Eur J Med Chem; 2021 Mar; 214():113229. PubMed ID: 33550186
[TBL] [Abstract][Full Text] [Related]
2. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
Eissa IH; Dahab MA; Ibrahim MK; Alsaif NA; Alanazi AZ; Eissa SI; Mehany ABM; Beauchemin AM
Bioorg Chem; 2021 Jul; 112():104965. PubMed ID: 34020238
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors.
Romagnoli R; Oliva P; Salvador MK; Camacho ME; Padroni C; Brancale A; Ferla S; Hamel E; Ronca R; Grillo E; Bortolozzi R; Rruga F; Mariotto E; Viola G
Eur J Med Chem; 2019 Nov; 181():111577. PubMed ID: 31400707
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
Liu R; Zhang S; Huang M; Guo Z; Li L; Li M; Wu L; Guan Q; Zhang W
Bioorg Chem; 2021 Oct; 115():105220. PubMed ID: 34352709
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.
Sun J; Chen L; Liu C; Wang Z; Zuo D; Pan J; Qi H; Bao K; Wu Y; Zhang W
Chem Biol Drug Des; 2015 Dec; 86(6):1541-7. PubMed ID: 26202587
[TBL] [Abstract][Full Text] [Related]
6. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.
Yang F; He CP; Diao PC; Hong KH; Rao JJ; Zhao PL
Bioorg Med Chem Lett; 2019 Jan; 29(1):22-27. PubMed ID: 30448234
[TBL] [Abstract][Full Text] [Related]
7. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G
Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790
[TBL] [Abstract][Full Text] [Related]
8. Sea Urchin Embryo Model As a Reliable in Vivo Phenotypic Screen to Characterize Selective Antimitotic Molecules. Comparative evaluation of Combretapyrazoles, -isoxazoles, -1,2,3-triazoles, and -pyrroles as Tubulin-Binding Agents.
Semenova MN; Demchuk DV; Tsyganov DV; Chernysheva NB; Samet AV; Silyanova EA; Kislyi VP; Maksimenko AS; Varakutin AE; Konyushkin LD; Raihstat MM; Kiselyov AS; Semenov VV
ACS Comb Sci; 2018 Dec; 20(12):700-721. PubMed ID: 30452225
[TBL] [Abstract][Full Text] [Related]
9. The Design, Synthesis, and Biological Activities of Pyrrole-Based Carboxamides: The Novel Tubulin Inhibitors Targeting the Colchicine-Binding Site.
Boichuk S; Galembikova A; Syuzov K; Dunaev P; Bikinieva F; Aukhadieva A; Zykova S; Igidov N; Gankova K; Novikova M; Kopnin P
Molecules; 2021 Sep; 26(19):. PubMed ID: 34641324
[TBL] [Abstract][Full Text] [Related]
10. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
Cui YJ; Ma CC; Zhang CM; Tang LQ; Liu ZP
Eur J Med Chem; 2020 Feb; 187():111968. PubMed ID: 31865012
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R; Baraldi PG; Carrion MD; Lopez Cara C; Preti D; Fruttarolo F; Pavani MG; Tabrizi MA; Tolomeo M; Grimaudo S; Di Cristina A; Balzarini J; Hadfield JA; Brancale A; Hamel E
J Med Chem; 2007 May; 50(9):2273-7. PubMed ID: 17419607
[TBL] [Abstract][Full Text] [Related]
12. Discovery of dihydrofuranoallocolchicinoids - Highly potent antimitotic agents with low acute toxicity.
Shchegravina ES; Svirshchevskaya EV; Combes S; Allegro D; Barbier P; Gigant B; Varela PF; Gavryushin AE; Kobanova DA; Shchekotikhin AE; Fedorov AY
Eur J Med Chem; 2020 Dec; 207():112724. PubMed ID: 32827941
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
Stefański T; Mikstacka R; Kurczab R; Dutkiewicz Z; Kucińska M; Murias M; Zielińska-Przyjemska M; Cichocki M; Teubert A; Kaczmarek M; Hogendorf A; Sobiak S
Eur J Med Chem; 2018 Jan; 144():797-816. PubMed ID: 29291446
[TBL] [Abstract][Full Text] [Related]
14. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
Chang JY; Yang MF; Chang CY; Chen CM; Kuo CC; Liou JP
J Med Chem; 2006 Oct; 49(21):6412-5. PubMed ID: 17034147
[TBL] [Abstract][Full Text] [Related]
15. New indolesulfonamide derivatives targeting the colchicine site of tubulin: synthesis, anti-tumour activity, structure-activity relationships, and molecular modelling.
Vicente-Blázquez A; González M; Medarde M; Mollinedo F; Peláez R
J Enzyme Inhib Med Chem; 2021 Dec; 36(1):2025-2044. PubMed ID: 34514909
[TBL] [Abstract][Full Text] [Related]
16. Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
Ibrahim TS; Hawwas MM; Malebari AM; Taher ES; Omar AM; Neamatallah T; Abdel-Samii ZK; Safo MK; Elshaier YAMM
J Enzyme Inhib Med Chem; 2021 Dec; 36(1):802-818. PubMed ID: 33730937
[TBL] [Abstract][Full Text] [Related]
17. Discovery of highly potent tubulin polymerization inhibitors: Design, synthesis, and structure-activity relationships of novel 2,7-diaryl-[1,2,4]triazolo[1,5-a]pyrimidines.
Huo XS; Jian XE; Ou-Yang J; Chen L; Yang F; Lv DX; You WW; Rao JJ; Zhao PL
Eur J Med Chem; 2021 Aug; 220():113449. PubMed ID: 33895499
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors.
Oliva P; Romagnoli R; Manfredini S; Brancale A; Ferla S; Hamel E; Ronca R; Maccarinelli F; Giacomini A; Rruga F; Mariotto E; Viola G; Bortolozzi R
Eur J Med Chem; 2020 Aug; 200():112448. PubMed ID: 32417696
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and bioevaluation of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazoles as tubulin polymerization inhibitors.
Liu R; Huang M; Zhang S; Li L; Li M; Sun J; Wu L; Guan Q; Zhang W
Eur J Med Chem; 2021 Dec; 226():113826. PubMed ID: 34571171
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological evaluation of 1-benzyl-N-(2-(phenylamino)pyridin-3-yl)-1H-1,2,3-triazole-4-carboxamides as antimitotic agents.
Prasad B; Lakshma Nayak V; Srikanth PS; Baig MF; Subba Reddy NV; Babu KS; Kamal A
Bioorg Chem; 2019 Mar; 83():535-548. PubMed ID: 30472555
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
