498 related articles for article (PubMed ID: 33550186)
21. Potent colchicine-site ligands with improved intrinsic solubility by replacement of the 3,4,5-trimethoxyphenyl ring with a 2-methylsulfanyl-6-methoxypyridine ring.
Álvarez R; Aramburu L; Gajate C; Vicente-Blázquez A; Mollinedo F; Medarde M; Peláez R
Bioorg Chem; 2020 May; 98():103755. PubMed ID: 32200330
[TBL] [Abstract][Full Text] [Related]
22. Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.
Pang Y; Lin H; Ou C; Cao Y; An B; Yan J; Li X
Eur J Med Chem; 2019 Nov; 182():111670. PubMed ID: 31499359
[TBL] [Abstract][Full Text] [Related]
23. Modification of the phenyl ring B of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates by pyridinyl moiety leads to novel antimitotics targeting the colchicine-binding site.
Ouellette V; Bouzriba C; Chavez Alvarez AC; Hamel-Côté G; Fortin S
Bioorg Med Chem Lett; 2024 Jun; 105():129745. PubMed ID: 38614151
[TBL] [Abstract][Full Text] [Related]
24. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Zhou P; Liang Y; Zhang H; Jiang H; Feng K; Xu P; Wang J; Wang X; Ding K; Luo C; Liu M; Wang Y
Eur J Med Chem; 2018 Jan; 144():817-842. PubMed ID: 29306206
[TBL] [Abstract][Full Text] [Related]
25. Structure-activity relationships and antiproliferative effects of 1,2,3,4-4H-quinoxaline derivatives as tubulin polymerization inhibitors.
Liang T; Zhou X; Lu L; Dong H; Zhang Y; Xu Y; Qi J; Zhang Y; Wang J
Bioorg Chem; 2021 May; 110():104793. PubMed ID: 33770673
[TBL] [Abstract][Full Text] [Related]
26. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
Li G; Wang Y; Li L; Ren Y; Deng X; Liu J; Wang W; Luo M; Liu S; Chen J
Eur J Med Chem; 2020 Sep; 202():112519. PubMed ID: 32650183
[TBL] [Abstract][Full Text] [Related]
27. Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation.
Hagras M; El Deeb MA; Elzahabi HSA; Elkaeed EB; Mehany ABM; Eissa IH
J Enzyme Inhib Med Chem; 2021 Dec; 36(1):640-658. PubMed ID: 33588683
[TBL] [Abstract][Full Text] [Related]
28. Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles.
Romagnoli R; Baraldi PG; Salvador MK; Prencipe F; Bertolasi V; Cancellieri M; Brancale A; Hamel E; Castagliuolo I; Consolaro F; Porcù E; Basso G; Viola G
J Med Chem; 2014 Aug; 57(15):6795-808. PubMed ID: 25025853
[TBL] [Abstract][Full Text] [Related]
29. Design, synthesis and antitumor evaluation of novel chiral diaryl substituted azetidin-2-one derivatives as tubulin polymerization inhibitors.
Liang Y; Zhang M; Zhou P; Liu M; Li J; Wang Y
Bioorg Chem; 2021 Oct; 115():105239. PubMed ID: 34399321
[TBL] [Abstract][Full Text] [Related]
30. New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer.
La Regina G; Bai R; Coluccia A; Famiglini V; Pelliccia S; Passacantilli S; Mazzoccoli C; Ruggieri V; Sisinni L; Bolognesi A; Rensen WM; Miele A; Nalli M; Alfonsi R; Di Marcotullio L; Gulino A; Brancale A; Novellino E; Dondio G; Vultaggio S; Varasi M; Mercurio C; Hamel E; Lavia P; Silvestri R
J Med Chem; 2014 Aug; 57(15):6531-52. PubMed ID: 25025991
[TBL] [Abstract][Full Text] [Related]
31. Design, synthesis and biological evaluation of colchicine glycoconjugates as tubulin polymerization inhibitors.
Wang Z; Liu R; Zhang X; Chang X; Gao M; Zhang S; Guan Q; Sun J; Zuo D; Zhang W
Bioorg Med Chem; 2022 Mar; 58():116671. PubMed ID: 35193066
[TBL] [Abstract][Full Text] [Related]
32. Synthesis, biological evaluation, and molecular modelling of new naphthalene-chalcone derivatives as potential anticancer agents on MCF-7 breast cancer cells by targeting tubulin colchicine binding site.
Wang G; Liu W; Gong Z; Huang Y; Li Y; Peng Z
J Enzyme Inhib Med Chem; 2020 Dec; 35(1):139-144. PubMed ID: 31724435
[TBL] [Abstract][Full Text] [Related]
33. Synthesis, biological evaluation, and structure-activity relationships of new tubulin polymerization inhibitors based on 5-amino-1,2,4-triazole scaffold.
Yang F; Chen L; Lai JM; Jian XE; Lv DX; Yuan LL; Liu YX; Liang FT; Zheng XL; Li XL; Wei LY; You WW; Zhao PL
Bioorg Med Chem Lett; 2021 Apr; 38():127880. PubMed ID: 33636303
[TBL] [Abstract][Full Text] [Related]
34. A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitors.
Barnes NG; Parker AW; Ahmed Mal Ullah AA; Ragazzon PA; Hadfield JA
Bioorg Med Chem; 2020 Oct; 28(19):115684. PubMed ID: 32912434
[TBL] [Abstract][Full Text] [Related]
35. Design, synthesis, and evaluations of the antiproliferative activity and aqueous solubility of novel carbazole sulfonamide derivatives as antitumor agents.
Sun L; Wang C; Hu X; Wu Y; Jiang Z; Li Z; Chen X; Hu L
Bioorg Chem; 2020 Jun; 99():103766. PubMed ID: 32247110
[TBL] [Abstract][Full Text] [Related]
36. Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities.
Yang F; Yu LZ; Diao PC; Jian XE; Zhou MF; Jiang CS; You WW; Ma WF; Zhao PL
Bioorg Chem; 2019 Nov; 92():103260. PubMed ID: 31525523
[TBL] [Abstract][Full Text] [Related]
37. Design, synthesis and structure-activity relationship of 3,6-diaryl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines as novel tubulin inhibitors.
Xu Q; Bao K; Sun M; Xu J; Wang Y; Tian H; Zuo D; Guan Q; Wu Y; Zhang W
Sci Rep; 2017 Sep; 7(1):11997. PubMed ID: 28931885
[TBL] [Abstract][Full Text] [Related]
38. Design, synthesis and biological evaluation of novel imidazole-chalcone derivatives as potential anticancer agents and tubulin polymerization inhibitors.
Rahimzadeh Oskuei S; Mirzaei S; Reza Jafari-Nik M; Hadizadeh F; Eisvand F; Mosaffa F; Ghodsi R
Bioorg Chem; 2021 Jul; 112():104904. PubMed ID: 33933802
[TBL] [Abstract][Full Text] [Related]
39. Tubulin inhibitors: Discovery of a new scaffold targeting extra-binding residues within the colchicine site through anchoring substituents properly adapted to their pocket by a semi-flexible linker.
Maklad RM; AbdelHafez EMN; Abdelhamid D; Aly OM
Bioorg Chem; 2020 Jun; 99():103767. PubMed ID: 32325332
[TBL] [Abstract][Full Text] [Related]
40. Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4-triazoles as potential combretastatin analogues.
Mustafa M; Abdelhamid D; Abdelhafez EMN; Ibrahim MAA; Gamal-Eldeen AM; Aly OM
Eur J Med Chem; 2017 Dec; 141():293-305. PubMed ID: 29031074
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]