BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

291 related articles for article (PubMed ID: 33556373)

  • 1. Insights into the catalytic properties of the mitochondrial rhomboid protease PARL.
    Lysyk L; Brassard R; Arutyunova E; Siebert V; Jiang Z; Takyi E; Morrison M; Young HS; Lemberg MK; O'Donoghue AJ; Lemieux MJ
    J Biol Chem; 2021; 296():100383. PubMed ID: 33556373
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rhomboid protease PARL mediates the mitochondrial membrane potential loss-induced cleavage of PGAM5.
    Sekine S; Kanamaru Y; Koike M; Nishihara A; Okada M; Kinoshita H; Kamiyama M; Maruyama J; Uchiyama Y; Ishihara N; Takeda K; Ichijo H
    J Biol Chem; 2012 Oct; 287(41):34635-45. PubMed ID: 22915595
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PARL Protease: A Glimpse at Intramembrane Proteolysis in the Inner Mitochondrial Membrane.
    Lysyk L; Brassard R; Touret N; Lemieux MJ
    J Mol Biol; 2020 Aug; 432(18):5052-5062. PubMed ID: 32320686
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cleavage of mitochondrial homeostasis regulator PGAM5 by the intramembrane protease PARL is governed by transmembrane helix dynamics and oligomeric state.
    Siebert V; Silber M; Heuten E; Muhle-Goll C; Lemberg MK
    J Biol Chem; 2022 Sep; 298(9):102321. PubMed ID: 35921890
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L.
    Wai T; Saita S; Nolte H; Müller S; König T; Richter-Dennerlein R; Sprenger HG; Madrenas J; Mühlmeister M; Brandt U; Krüger M; Langer T
    EMBO Rep; 2016 Dec; 17(12):1844-1856. PubMed ID: 27737933
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.
    Saita S; Nolte H; Fiedler KU; Kashkar H; Venne AS; Zahedi RP; Krüger M; Langer T
    Nat Cell Biol; 2017 Apr; 19(4):318-328. PubMed ID: 28288130
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis.
    Yan C; Gong L; Chen L; Xu M; Abou-Hamdan H; Tang M; Désaubry L; Song Z
    Autophagy; 2020 Mar; 16(3):419-434. PubMed ID: 31177901
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chemical Blockage of the Mitochondrial Rhomboid Protease PARL by Novel Ketoamide Inhibitors Reveals Its Role in PINK1/Parkin-Dependent Mitophagy.
    Poláchová E; Bach K; Heuten E; Stanchev S; Tichá A; Lampe P; Majer P; Langer T; Lemberg MK; Stříšovský K
    J Med Chem; 2023 Jan; 66(1):251-265. PubMed ID: 36540942
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural and mechanistic basis of Parl activity and regulation.
    Jeyaraju DV; McBride HM; Hill RB; Pellegrini L
    Cell Death Differ; 2011 Sep; 18(9):1531-9. PubMed ID: 21415861
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking.
    Meissner C; Lorenz H; Weihofen A; Selkoe DJ; Lemberg MK
    J Neurochem; 2011 Jun; 117(5):856-67. PubMed ID: 21426348
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL.
    Jin SM; Lazarou M; Wang C; Kane LA; Narendra DP; Youle RJ
    J Cell Biol; 2010 Nov; 191(5):933-42. PubMed ID: 21115803
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A cut short to death: Parl and Opa1 in the regulation of mitochondrial morphology and apoptosis.
    Pellegrini L; Scorrano L
    Cell Death Differ; 2007 Jul; 14(7):1275-84. PubMed ID: 17464328
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria.
    Saita S; Tatsuta T; Lampe PA; König T; Ohba Y; Langer T
    EMBO J; 2018 Feb; 37(4):. PubMed ID: 29301859
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism.
    Shi G; McQuibban GA
    Cell Rep; 2017 Feb; 18(6):1458-1472. PubMed ID: 28178523
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy.
    Meissner C; Lorenz H; Hehn B; Lemberg MK
    Autophagy; 2015; 11(9):1484-98. PubMed ID: 26101826
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PINK1 cleavage at position A103 by the mitochondrial protease PARL.
    Deas E; Plun-Favreau H; Gandhi S; Desmond H; Kjaer S; Loh SH; Renton AE; Harvey RJ; Whitworth AJ; Martins LM; Abramov AY; Wood NW
    Hum Mol Genet; 2011 Mar; 20(5):867-79. PubMed ID: 21138942
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Syntaxin 17 regulates the localization and function of PGAM5 in mitochondrial division and mitophagy.
    Sugo M; Kimura H; Arasaki K; Amemiya T; Hirota N; Dohmae N; Imai Y; Inoshita T; Shiba-Fukushima K; Hattori N; Cheng J; Fujimoto T; Wakana Y; Inoue H; Tagaya M
    EMBO J; 2018 Nov; 37(21):. PubMed ID: 30237312
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expression and Purification of Human Mitochondrial Intramembrane Protease PARL.
    Arutyunova E; Lysyk L; Morrison M; Brooks C; Joanne Lemieux M
    Methods Mol Biol; 2021; 2302():1-20. PubMed ID: 33877619
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Self-regulated cleavage of the mitochondrial intramembrane-cleaving protease PARL yields Pbeta, a nuclear-targeted peptide.
    Sík A; Passer BJ; Koonin EV; Pellegrini L
    J Biol Chem; 2004 Apr; 279(15):15323-9. PubMed ID: 14732705
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease.
    Shi G; Lee JR; Grimes DA; Racacho L; Ye D; Yang H; Ross OA; Farrer M; McQuibban GA; Bulman DE
    Hum Mol Genet; 2011 May; 20(10):1966-74. PubMed ID: 21355049
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.