793 related articles for article (PubMed ID: 33563726)
1. REST Protects Dopaminergic Neurons from Mitochondrial and α-Synuclein Oligomer Pathology in an Alpha Synuclein Overexpressing BAC-Transgenic Mouse Model.
Ryan BJ; Bengoa-Vergniory N; Williamson M; Kirkiz E; Roberts R; Corda G; Sloan M; Saqlain S; Cherubini M; Poppinga J; Bogtofte H; Cioroch M; Hester S; Wade-Martins R
J Neurosci; 2021 Apr; 41(16):3731-3746. PubMed ID: 33563726
[TBL] [Abstract][Full Text] [Related]
2. PGC-1α activity in nigral dopamine neurons determines vulnerability to α-synuclein.
Ciron C; Zheng L; Bobela W; Knott GW; Leone TC; Kelly DP; Schneider BL
Acta Neuropathol Commun; 2015 Apr; 3():16. PubMed ID: 25853296
[TBL] [Abstract][Full Text] [Related]
3. Mutant α-Synuclein Overexpression Induces Stressless Pacemaking in Vagal Motoneurons at Risk in Parkinson's Disease.
Lasser-Katz E; Simchovitz A; Chiu WH; Oertel WH; Sharon R; Soreq H; Roeper J; Goldberg JA
J Neurosci; 2017 Jan; 37(1):47-57. PubMed ID: 28053029
[TBL] [Abstract][Full Text] [Related]
4. Insulin Resistance Promotes Parkinson's Disease through Aberrant Expression of α-Synuclein, Mitochondrial Dysfunction, and Deregulation of the Polo-Like Kinase 2 Signaling.
Hong CT; Chen KY; Wang W; Chiu JY; Wu D; Chao TY; Hu CJ; Chau KD; Bamodu OA
Cells; 2020 Mar; 9(3):. PubMed ID: 32192190
[No Abstract] [Full Text] [Related]
5. Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization.
Eschbach J; von Einem B; Müller K; Bayer H; Scheffold A; Morrison BE; Rudolph KL; Thal DR; Witting A; Weydt P; Otto M; Fauler M; Liss B; McLean PJ; Spada AR; Ludolph AC; Weishaupt JH; Danzer KM
Ann Neurol; 2015 Jan; 77(1):15-32. PubMed ID: 25363075
[TBL] [Abstract][Full Text] [Related]
6. Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function.
Ciron C; Lengacher S; Dusonchet J; Aebischer P; Schneider BL
Hum Mol Genet; 2012 Apr; 21(8):1861-76. PubMed ID: 22246294
[TBL] [Abstract][Full Text] [Related]
7. Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity.
Hu D; Sun X; Liao X; Zhang X; Zarabi S; Schimmer A; Hong Y; Ford C; Luo Y; Qi X
Acta Neuropathol; 2019 Jun; 137(6):939-960. PubMed ID: 30877431
[TBL] [Abstract][Full Text] [Related]
8. Region specific mitochondrial impairment in mice with widespread overexpression of alpha-synuclein.
Subramaniam SR; Vergnes L; Franich NR; Reue K; Chesselet MF
Neurobiol Dis; 2014 Oct; 70():204-13. PubMed ID: 25016198
[TBL] [Abstract][Full Text] [Related]
9. Benzo(a)pyrene exposure in utero exacerbates Parkinson's Disease (PD)-like α-synucleinopathy in A53T human alpha-synuclein transgenic mice.
Xu W; Qi Y; Gao Y; Quan H; Li Q; Zhou H; Huang J
Toxicol Appl Pharmacol; 2021 Sep; 427():115658. PubMed ID: 34332006
[TBL] [Abstract][Full Text] [Related]
10. Rapid Induction of Dopaminergic Neuron Loss Accompanied by Lewy Body-Like Inclusions in A53T BAC-SNCA Transgenic Mice.
Okuda S; Uemura N; Sawamura M; Taguchi T; Ikuno M; Uemura MT; Yamakado H; Takahashi R
Neurotherapeutics; 2022 Jan; 19(1):289-304. PubMed ID: 34935120
[TBL] [Abstract][Full Text] [Related]
11. α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model.
Taguchi T; Ikuno M; Hondo M; Parajuli LK; Taguchi K; Ueda J; Sawamura M; Okuda S; Nakanishi E; Hara J; Uemura N; Hatanaka Y; Ayaki T; Matsuzawa S; Tanaka M; El-Agnaf OMA; Koike M; Yanagisawa M; Uemura MT; Yamakado H; Takahashi R
Brain; 2020 Jan; 143(1):249-265. PubMed ID: 31816026
[TBL] [Abstract][Full Text] [Related]
12. PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model.
Chiu CC; Lu CS; Weng YH; Chen YL; Huang YZ; Chen RS; Cheng YC; Huang YC; Liu YC; Lai SC; Lin KJ; Lin YW; Chen YJ; Chen CL; Yeh TH; Wang HL
Mol Neurobiol; 2019 Jun; 56(6):3835-3853. PubMed ID: 30088174
[TBL] [Abstract][Full Text] [Related]
13. Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo.
Rockenstein E; Nuber S; Overk CR; Ubhi K; Mante M; Patrick C; Adame A; Trejo-Morales M; Gerez J; Picotti P; Jensen PH; Campioni S; Riek R; Winkler J; Gage FH; Winner B; Masliah E
Brain; 2014 May; 137(Pt 5):1496-513. PubMed ID: 24662516
[TBL] [Abstract][Full Text] [Related]
14. Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation.
Liu G; Yu J; Ding J; Xie C; Sun L; Rudenko I; Zheng W; Sastry N; Luo J; Rudow G; Troncoso JC; Cai H
J Clin Invest; 2014 Jul; 124(7):3032-46. PubMed ID: 24865427
[TBL] [Abstract][Full Text] [Related]
15. Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease.
Mudò G; Mäkelä J; Di Liberto V; Tselykh TV; Olivieri M; Piepponen P; Eriksson O; Mälkiä A; Bonomo A; Kairisalo M; Aguirre JA; Korhonen L; Belluardo N; Lindholm D
Cell Mol Life Sci; 2012 Apr; 69(7):1153-65. PubMed ID: 21984601
[TBL] [Abstract][Full Text] [Related]
16. Chronic Mild Gut Inflammation Accelerates Brain Neuropathology and Motor Dysfunction in α-Synuclein Mutant Mice.
Kishimoto Y; Zhu W; Hosoda W; Sen JM; Mattson MP
Neuromolecular Med; 2019 Sep; 21(3):239-249. PubMed ID: 31079293
[TBL] [Abstract][Full Text] [Related]
17. Pgc-1α overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased Bdnf.
Clark J; Silvaggi JM; Kiselak T; Zheng K; Clore EL; Dai Y; Bass CE; Simon DK
PLoS One; 2012; 7(11):e48925. PubMed ID: 23145024
[TBL] [Abstract][Full Text] [Related]
18. Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse.
Taylor TN; Potgieter D; Anwar S; Senior SL; Janezic S; Threlfell S; Ryan B; Parkkinen L; Deltheil T; Cioroch M; Livieratos A; Oliver PL; Jennings KA; Davies KE; Ansorge O; Bannerman DM; Cragg SJ; Wade-Martins R
Neurobiol Dis; 2014 Feb; 62():193-207. PubMed ID: 24121116
[TBL] [Abstract][Full Text] [Related]
19. Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons.
Richter F; Gao F; Medvedeva V; Lee P; Bove N; Fleming SM; Michaud M; Lemesre V; Patassini S; De La Rosa K; Mulligan CK; Sioshansi PC; Zhu C; Coppola G; Bordet T; Pruss RM; Chesselet MF
Neurobiol Dis; 2014 Sep; 69():263-75. PubMed ID: 24844147
[TBL] [Abstract][Full Text] [Related]
20. Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication.
Fukusumi H; Togo K; Sumida M; Nakamori M; Obika S; Baba K; Shofuda T; Ito D; Okano H; Mochizuki H; Kanemura Y
FEBS Open Bio; 2021 Feb; 11(2):354-366. PubMed ID: 33301617
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
