BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

334 related articles for article (PubMed ID: 33563814)

  • 1. Resistance to a Nucleoside Analog Antiviral Drug from More Rapid Extension of Drug-Containing Primers.
    Chen H; Lawler JL; Filman DJ; Hogle JM; Coen DM
    mBio; 2021 Feb; 12(1):. PubMed ID: 33563814
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism of ganciclovir-induced chain termination revealed by resistant viral polymerase mutants with reduced exonuclease activity.
    Chen H; Beardsley GP; Coen DM
    Proc Natl Acad Sci U S A; 2014 Dec; 111(49):17462-7. PubMed ID: 25422422
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Potency and Stereoselectivity of Cyclopropavir Triphosphate Action on Human Cytomegalovirus DNA Polymerase.
    Chen H; Li C; Zemlicka J; Gentry BG; Bowlin TL; Coen DM
    Antimicrob Agents Chemother; 2016 Jul; 60(7):4176-82. PubMed ID: 27139481
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus.
    Scott GM; Ng HL; Morton CJ; Parker MW; Rawlinson WD
    J Gen Virol; 2005 Aug; 86(Pt 8):2141-2151. PubMed ID: 16033961
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Contrasting effects of W781V and W780V mutations in helix N of herpes simplex virus 1 and human cytomegalovirus DNA polymerases on antiviral drug susceptibility.
    Piret J; Goyette N; Eckenroth BE; Drouot E; Götte M; Boivin G
    J Virol; 2015 Apr; 89(8):4636-44. PubMed ID: 25673718
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A point mutation in the human cytomegalovirus DNA polymerase gene selected in vitro by cidofovir confers a slow replication phenotype in cell culture.
    Cihlar T; Fuller MD; Mulato AS; Cherrington JM
    Virology; 1998 Sep; 248(2):382-93. PubMed ID: 9721246
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amino acid changes within conserved region III of the herpes simplex virus and human cytomegalovirus DNA polymerases confer resistance to 4-oxo-dihydroquinolines, a novel class of herpesvirus antiviral agents.
    Thomsen DR; Oien NL; Hopkins TA; Knechtel ML; Brideau RJ; Wathen MW; Homa FL
    J Virol; 2003 Feb; 77(3):1868-76. PubMed ID: 12525621
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential impact of various substitutions at codon 715 in region II of HSV-1 and HCMV DNA polymerases.
    Zarrouk K; Zhu X; Goyette N; Piret J; Shi R; Boivin G
    Antiviral Res; 2021 Apr; 188():105046. PubMed ID: 33588012
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Resistance of human cytomegalovirus to ganciclovir/valganciclovir: a comprehensive review of putative resistance pathways.
    Komatsu TE; Pikis A; Naeger LK; Harrington PR
    Antiviral Res; 2014 Jan; 101():12-25. PubMed ID: 24184129
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison of human cytomegalovirus DNA polymerase activity for ganciclovir-resistant and -sensitive clinical strains.
    Kariya M; Mori S; Eizuru Y
    Antiviral Res; 2000 Feb; 45(2):115-22. PubMed ID: 10809020
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cidofovir Diphosphate Inhibits Adenovirus 5 DNA Polymerase via both Nonobligate Chain Termination and Direct Inhibition, and Polymerase Mutations Confer Cidofovir Resistance on Intact Virus.
    Chamberlain JM; Sortino K; Sethna P; Bae A; Lanier R; Bambara RA; Dewhurst S
    Antimicrob Agents Chemother; 2019 Jan; 63(1):. PubMed ID: 30397065
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments.
    Cihlar T; Fuller MD; Cherrington JM
    J Virol; 1998 Jul; 72(7):5927-36. PubMed ID: 9621055
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Viral DNA polymerase mutations associated with drug resistance in human cytomegalovirus.
    Chou S; Lurain NS; Thompson KD; Miner RC; Drew WL
    J Infect Dis; 2003 Jul; 188(1):32-9. PubMed ID: 12825168
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural determinants in human DNA polymerase gamma account for mitochondrial toxicity from nucleoside analogs.
    Lim SE; Ponamarev MV; Longley MJ; Copeland WC
    J Mol Biol; 2003 May; 329(1):45-57. PubMed ID: 12742017
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of helix P of the human cytomegalovirus DNA polymerase in resistance and hypersusceptibility to the antiviral drug foscarnet.
    Tchesnokov EP; Gilbert C; Boivin G; Götte M
    J Virol; 2006 Feb; 80(3):1440-50. PubMed ID: 16415021
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lobucavir is phosphorylated in human cytomegalovirus-infected and -uninfected cells and inhibits the viral DNA polymerase.
    Tenney DJ; Yamanaka G; Voss SM; Cianci CW; Tuomari AV; Sheaffer AK; Alam M; Colonno RJ
    Antimicrob Agents Chemother; 1997 Dec; 41(12):2680-5. PubMed ID: 9420038
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rapid semiquantitative real-time PCR for the detection of human cytomegalovirus UL97 mutations conferring ganciclovir resistance.
    Göhring K; Mikeler E; Jahn G; Rohde F; Hamprecht K
    Antivir Ther; 2008; 13(3):461-6. PubMed ID: 18572760
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir.
    Zhang SM; Rehling D; Jemth AS; Throup A; Landázuri N; Almlöf I; Göttmann M; Valerie NCK; Borhade SR; Wakchaure P; Page BDG; Desroses M; Homan EJ; Scobie M; Rudd SG; Berglund UW; Söderberg-Nauclér C; Stenmark P; Helleday T
    Cell Chem Biol; 2021 Dec; 28(12):1693-1702.e6. PubMed ID: 34192523
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human cytomegalovirus resistance to deoxyribosylindole nucleosides maps to a transversion mutation in the terminase subunit-encoding gene UL89.
    Gentry BG; Phan Q; Hall ED; Breitenbach JM; Borysko KZ; Kamil JP; Townsend LB; Drach JC
    Antimicrob Agents Chemother; 2015 Jan; 59(1):226-32. PubMed ID: 25348532
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Contrasting effect of new HCMV pUL54 mutations on antiviral drug susceptibility: Benefits and limits of 3D analysis.
    Andouard D; Mazeron MC; Ligat G; Couvreux A; Pouteil-Noble C; Cahen R; Yasdanpanah Y; Deering M; Viget N; Alain S; Hantz S
    Antiviral Res; 2016 May; 129():115-119. PubMed ID: 26872863
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.