317 related articles for article (PubMed ID: 33567268)
21. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation.
Maniaci C; Hughes SJ; Testa A; Chen W; Lamont DJ; Rocha S; Alessi DR; Romeo R; Ciulli A
Nat Commun; 2017 Oct; 8(1):830. PubMed ID: 29018234
[TBL] [Abstract][Full Text] [Related]
22. [Development of Protein Knockdown Technology as Emerging Drug Discovery Strategy].
Ohoka N
Yakugaku Zasshi; 2018; 138(9):1135-1143. PubMed ID: 30175757
[TBL] [Abstract][Full Text] [Related]
23. DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligase.
Heir P; Sufan RI; Greer SN; Poon BP; Lee JE; Ohh M
Mol Cell Biol; 2013 Apr; 33(8):1621-31. PubMed ID: 23401859
[TBL] [Abstract][Full Text] [Related]
24. Trip12 is an E3 ubiquitin ligase for USP7/HAUSP involved in the DNA damage response.
Liu X; Yang X; Li Y; Zhao S; Li C; Ma P; Mao B
FEBS Lett; 2016 Dec; 590(23):4213-4222. PubMed ID: 27800609
[TBL] [Abstract][Full Text] [Related]
25. Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase.
French ME; Klosowiak JL; Aslanian A; Reed SI; Yates JR; Hunter T
J Biol Chem; 2017 Jun; 292(25):10398-10413. PubMed ID: 28461335
[No Abstract] [Full Text] [Related]
26. New strategy for renal fibrosis: Targeting Smad3 proteins for ubiquitination and degradation.
Wang X; Feng S; Fan J; Li X; Wen Q; Luo N
Biochem Pharmacol; 2016 Sep; 116():200-9. PubMed ID: 27473774
[TBL] [Abstract][Full Text] [Related]
27. Structural basis of PROTAC cooperative recognition for selective protein degradation.
Gadd MS; Testa A; Lucas X; Chan KH; Chen W; Lamont DJ; Zengerle M; Ciulli A
Nat Chem Biol; 2017 May; 13(5):514-521. PubMed ID: 28288108
[TBL] [Abstract][Full Text] [Related]
28. CKIP-1 couples Smurf1 ubiquitin ligase with Rpt6 subunit of proteasome to promote substrate degradation.
Wang Y; Nie J; Wang Y; Zhang L; Lu K; Xing G; Xie P; He F; Zhang L
EMBO Rep; 2012 Nov; 13(11):1004-11. PubMed ID: 23032291
[TBL] [Abstract][Full Text] [Related]
29. Assembly and specific recognition of k29- and k33-linked polyubiquitin.
Michel MA; Elliott PR; Swatek KN; Simicek M; Pruneda JN; Wagstaff JL; Freund SM; Komander D
Mol Cell; 2015 Apr; 58(1):95-109. PubMed ID: 25752577
[TBL] [Abstract][Full Text] [Related]
30. Phospholipase D2 promotes degradation of hypoxia-inducible factor-1α independent of lipase activity.
Park MH; Bae SS; Choi KY; Min do S
Exp Mol Med; 2015 Nov; 47(11):e196. PubMed ID: 26611735
[TBL] [Abstract][Full Text] [Related]
31. The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma.
Clifford SC; Astuti D; Hooper L; Maxwell PH; Ratcliffe PJ; Maher ER
Oncogene; 2001 Aug; 20(36):5067-74. PubMed ID: 11526493
[TBL] [Abstract][Full Text] [Related]
32. PROTAC-mediated crosstalk between E3 ligases.
Steinebach C; Kehm H; Lindner S; Vu LP; Köpff S; López Mármol Á; Weiler C; Wagner KG; Reichenzeller M; Krönke J; Gütschow M
Chem Commun (Camb); 2019 Feb; 55(12):1821-1824. PubMed ID: 30672516
[TBL] [Abstract][Full Text] [Related]
33. A Cell-Based Target Engagement Assay for the Identification of Cereblon E3 Ubiquitin Ligase Ligands and Their Application in HDAC6 Degraders.
Yang K; Zhao Y; Nie X; Wu H; Wang B; Almodovar-Rivera CM; Xie H; Tang W
Cell Chem Biol; 2020 Jul; 27(7):866-876.e8. PubMed ID: 32413286
[TBL] [Abstract][Full Text] [Related]
34. UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.
Alexandru G; Graumann J; Smith GT; Kolawa NJ; Fang R; Deshaies RJ
Cell; 2008 Sep; 134(5):804-16. PubMed ID: 18775313
[TBL] [Abstract][Full Text] [Related]
35. PROTACs: An Emerging Targeting Technique for Protein Degradation in Drug Discovery.
Gu S; Cui D; Chen X; Xiong X; Zhao Y
Bioessays; 2018 Apr; 40(4):e1700247. PubMed ID: 29473971
[TBL] [Abstract][Full Text] [Related]
36. Ufd2p synthesizes branched ubiquitin chains to promote the degradation of substrates modified with atypical chains.
Liu C; Liu W; Ye Y; Li W
Nat Commun; 2017 Feb; 8():14274. PubMed ID: 28165462
[TBL] [Abstract][Full Text] [Related]
37. The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin.
Wu-Baer F; Lagrazon K; Yuan W; Baer R
J Biol Chem; 2003 Sep; 278(37):34743-6. PubMed ID: 12890688
[TBL] [Abstract][Full Text] [Related]
38. Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation.
Hong SH; Osa A; Huang OW; Wertz IE; Nomura DK
bioRxiv; 2023 Nov; ():. PubMed ID: 37904950
[TBL] [Abstract][Full Text] [Related]
39. Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead.
Bondeson DP; Smith BE; Burslem GM; Buhimschi AD; Hines J; Jaime-Figueroa S; Wang J; Hamman BD; Ishchenko A; Crews CM
Cell Chem Biol; 2018 Jan; 25(1):78-87.e5. PubMed ID: 29129718
[TBL] [Abstract][Full Text] [Related]
40. EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressors.
Cai QL; Knight JS; Verma SC; Zald P; Robertson ES
PLoS Pathog; 2006 Oct; 2(10):e116. PubMed ID: 17069461
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
