263 related articles for article (PubMed ID: 33576714)
1. Characterization of cytochrome P450s (CYP)-overexpressing HepG2 cells for assessing drug and chemical-induced liver toxicity.
Chen S; Wu Q; Li X; Li D; Mei N; Ning B; Puig M; Ren Z; Tolleson WH; Guo L
J Environ Sci Health C Toxicol Carcinog; 2021; 39(1):68-86. PubMed ID: 33576714
[TBL] [Abstract][Full Text] [Related]
2. Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity.
Xuan J; Chen S; Ning B; Tolleson WH; Guo L
Chem Biol Interact; 2016 Aug; 255():63-73. PubMed ID: 26477383
[TBL] [Abstract][Full Text] [Related]
3. The role of hepatic cytochrome P450s in the cytotoxicity of dronedarone.
Chen S; Wu Q; Ning B; Bryant M; Guo L
Arch Toxicol; 2018 Jun; 92(6):1969-1981. PubMed ID: 29616291
[TBL] [Abstract][Full Text] [Related]
4. The involvement of hepatic cytochrome P450s in the cytotoxicity of lapatinib.
Chen S; Li X; Li Y; He X; Bryant M; Qin X; Li F; Seo JE; Guo X; Mei N; Guo L
Toxicol Sci; 2023 Dec; 197(1):69-78. PubMed ID: 37788138
[TBL] [Abstract][Full Text] [Related]
5. The role of hepatic cytochrome P450s in the cytotoxicity of sertraline.
Chen S; Wu Q; Li X; Li D; Fan M; Ren Z; Bryant M; Mei N; Ning B; Guo L
Arch Toxicol; 2020 Jul; 94(7):2401-2411. PubMed ID: 32372212
[TBL] [Abstract][Full Text] [Related]
6. Study of the roles of cytochrome P450 (CYPs) in the metabolism and cytotoxicity of perhexiline.
Ren Z; Chen S; Qin X; Li F; Guo L
Arch Toxicol; 2022 Dec; 96(12):3219-3231. PubMed ID: 36083301
[TBL] [Abstract][Full Text] [Related]
7. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.
Westerink WM; Schoonen WG
Toxicol In Vitro; 2007 Dec; 21(8):1581-91. PubMed ID: 17637504
[TBL] [Abstract][Full Text] [Related]
8. Intraindividual Variation and Correlation of Cytochrome P450 Activities in Human Liver Microsomes.
Fang Y; Gao J; Wang T; Tian X; Gao N; Zhou J; Zhang HF; Wen Q; Jin H; Xing YR; Qiao HL
Mol Pharm; 2018 Nov; 15(11):5312-5318. PubMed ID: 30346185
[TBL] [Abstract][Full Text] [Related]
9. Comparison of the substrate specificities of human liver cytochrome P450s 2C9 and 2C18: application to the design of a specific substrate of CYP 2C18.
Minoletti C; Dijols S; Dansette PM; Mansuy D
Biochemistry; 1999 Jun; 38(24):7828-36. PubMed ID: 10387023
[TBL] [Abstract][Full Text] [Related]
10. Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.
Marill J; Cresteil T; Lanotte M; Chabot GG
Mol Pharmacol; 2000 Dec; 58(6):1341-8. PubMed ID: 11093772
[TBL] [Abstract][Full Text] [Related]
11. Ellipticine oxidation and DNA adduct formation in human hepatocytes is catalyzed by human cytochromes P450 and enhanced by cytochrome b5.
Stiborová M; Poljaková J; Martínková E; Ulrichová J; Simánek V; Dvořák Z; Frei E
Toxicology; 2012 Dec; 302(2-3):233-41. PubMed ID: 22917556
[TBL] [Abstract][Full Text] [Related]
12. Human cytochrome P450s involved in the metabolism of 9-cis- and 13-cis-retinoic acids.
Marill J; Capron CC; Idres N; Chabot GG
Biochem Pharmacol; 2002 Mar; 63(5):933-43. PubMed ID: 11911845
[TBL] [Abstract][Full Text] [Related]
13. Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomes.
Rifkind AB; Lee C; Chang TK; Waxman DJ
Arch Biochem Biophys; 1995 Jul; 320(2):380-9. PubMed ID: 7625847
[TBL] [Abstract][Full Text] [Related]
14. CYP3A4 is a major isoform responsible for oxidation of 7-hydroxy-Delta(8)-tetrahydrocannabinol to 7-oxo-delta(8)-tetrahydrocannabinol in human liver microsomes.
Matsunaga T; Kishi N; Higuchi S; Watanabe K; Ohshima T; Yamamoto I
Drug Metab Dispos; 2000 Nov; 28(11):1291-6. PubMed ID: 11038155
[TBL] [Abstract][Full Text] [Related]
15. Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells.
Rodríguez-Antona C; Donato MT; Boobis A; Edwards RJ; Watts PS; Castell JV; Gómez-Lechón MJ
Xenobiotica; 2002 Jun; 32(6):505-20. PubMed ID: 12160483
[TBL] [Abstract][Full Text] [Related]
16. Assessment of a dry extract from milk thistle (Silybum marianum) for interference with human liver cytochrome-P450 activities.
Doehmer J; Weiss G; McGregor GP; Appel K
Toxicol In Vitro; 2011 Feb; 25(1):21-7. PubMed ID: 20828605
[TBL] [Abstract][Full Text] [Related]
17. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
Butler AM; Murray M
J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
[TBL] [Abstract][Full Text] [Related]
18. Comparative cytochrome P450 -1A1, -2A6, -2B6, -2C, -2D6, -2E1, -3A5 and -4B1 expressions in human larynx tissue analysed at mRNA level.
Sarikaya D; Bilgen C; Kamataki T; Topcu Z
Biopharm Drug Dispos; 2006 Nov; 27(8):353-9. PubMed ID: 16894644
[TBL] [Abstract][Full Text] [Related]
19. The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers.
Šulc M; Indra R; Moserová M; Schmeiser HH; Frei E; Arlt VM; Stiborová M
Environ Mol Mutagen; 2016 Apr; 57(3):229-35. PubMed ID: 26919089
[TBL] [Abstract][Full Text] [Related]
20. The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity.
Wu Q; Ning B; Xuan J; Ren Z; Guo L; Bryant MS
Toxicol Lett; 2016 Jun; 253():55-62. PubMed ID: 27113703
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]