BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 33586321)

  • 1. Differential lysine-mediated allosteric regulation of plant dihydrodipicolinate synthase isoforms.
    Hall CJ; Lee M; Boarder MP; Mangion AM; Gendall AR; Panjikar S; Perugini MA; Soares da Costa TP
    FEBS J; 2021 Aug; 288(16):4973-4986. PubMed ID: 33586321
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of two dihydrodipicolinate synthase isoforms from Pseudomonas aeruginosa that differ in allosteric regulation.
    Impey RE; Panjikar S; Hall CJ; Bock LJ; Sutton JM; Perugini MA; Soares da Costa TP
    FEBS J; 2020 Jan; 287(2):386-400. PubMed ID: 31330085
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Exploring the allosteric mechanism of dihydrodipicolinate synthase by reverse engineering of the allosteric inhibitor binding sites and its application for lysine production.
    Geng F; Chen Z; Zheng P; Sun J; Zeng AP
    Appl Microbiol Biotechnol; 2013 Mar; 97(5):1963-71. PubMed ID: 22644522
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of a thermostable dihydrodipicolinate synthase from Thermoanaerobacter tengcongensis.
    Wolterink-van Loo S; Levisson M; Cabrières MC; Franssen MC; van der Oost J
    Extremophiles; 2008 May; 12(3):461-9. PubMed ID: 18340401
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural Determinants Defining the Allosteric Inhibition of an Essential Antibiotic Target.
    Soares da Costa TP; Desbois S; Dogovski C; Gorman MA; Ketaren NE; Paxman JJ; Siddiqui T; Zammit LM; Abbott BM; Robins-Browne RM; Parker MW; Jameson GB; Hall NE; Panjikar S; Perugini MA
    Structure; 2016 Aug; 24(8):1282-1291. PubMed ID: 27427481
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tyrosine 110 plays a critical role in regulating the allosteric inhibition of Campylobacter jejuni dihydrodipicolinate synthase by lysine.
    Conly CJ; Skovpen YV; Li S; Palmer DR; Sanders DA
    Biochemistry; 2014 Dec; 53(47):7396-406. PubMed ID: 25369463
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition.
    Atkinson SC; Dogovski C; Downton MT; Czabotar PE; Dobson RC; Gerrard JA; Wagner J; Perugini MA
    Plant Mol Biol; 2013 Mar; 81(4-5):431-46. PubMed ID: 23354837
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana.
    Griffin MD; Billakanti JM; Wason A; Keller S; Mertens HD; Atkinson SC; Dobson RC; Perugini MA; Gerrard JA; Pearce FG
    PLoS One; 2012; 7(7):e40318. PubMed ID: 22792278
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Feedback inhibition of dihydrodipicolinate synthase enzymes by L-lysine.
    Blickling S; Knäblein J
    Biol Chem; 1997; 378(3-4):207-10. PubMed ID: 9165072
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Arabidopsis thaliana dhdps gene encoding dihydrodipicolinate synthase, key enzyme of lysine biosynthesis, is expressed in a cell-specific manner.
    Vauterin M; Frankard V; Jacobs M
    Plant Mol Biol; 1999 Mar; 39(4):695-708. PubMed ID: 10350084
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Medicago truncatula dihydrodipicolinate synthase (DHDPS) enzymes display novel regulatory properties.
    Erzeel E; Van Bochaute P; Thu TT; Angenon G
    Plant Mol Biol; 2013 Mar; 81(4-5):401-15. PubMed ID: 23329373
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional rescue of a bacterial dapA auxotroph with a plant cDNA library selects for mutant clones encoding a feedback-insensitive dihydrodipicolinate synthase.
    Vauterin M; Frankard V; Jacobs M
    Plant J; 2000 Feb; 21(3):239-48. PubMed ID: 10758475
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Asparagine-84, a regulatory allosteric site residue, helps maintain the quaternary structure of Campylobacter jejuni dihydrodipicolinate synthase.
    Majdi Yazdi M; Saran S; Mrozowich T; Lehnert C; Patel TR; Sanders DAR; Palmer DRJ
    J Struct Biol; 2020 Jan; 209(1):107409. PubMed ID: 31678256
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis.
    Kefala G; Evans GL; Griffin MD; Devenish SR; Pearce FG; Perugini MA; Gerrard JA; Weiss MS; Dobson RC
    Biochem J; 2008 Apr; 411(2):351-60. PubMed ID: 18062777
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase.
    Dobson RC; Griffin MD; Devenish SR; Pearce FG; Hutton CA; Gerrard JA; Jameson GB; Perugini MA
    Protein Sci; 2008 Dec; 17(12):2080-90. PubMed ID: 18787203
    [TBL] [Abstract][Full Text] [Related]  

  • 16. How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?
    Soares da Costa TP; Muscroft-Taylor AC; Dobson RC; Devenish SR; Jameson GB; Gerrard JA
    Biochimie; 2010 Jul; 92(7):837-45. PubMed ID: 20353808
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.
    Dobson RC; Griffin MD; Jameson GB; Gerrard JA
    Acta Crystallogr D Biol Crystallogr; 2005 Aug; 61(Pt 8):1116-24. PubMed ID: 16041077
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of the bona fide DHDPS from a common plant pathogen.
    Atkinson SC; Hor L; Dogovski C; Dobson RC; Perugini MA
    Proteins; 2014 Sep; 82(9):1869-83. PubMed ID: 24677246
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Engineering a feedback inhibition-insensitive plant dihydrodipicolinate synthase to increase lysine content in Camelina sativa seeds.
    Huang A; Coutu C; Harrington M; Rozwadowski K; Hegedus DD
    Transgenic Res; 2022 Feb; 31(1):131-148. PubMed ID: 34802109
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dihydrodipicolinate Synthase: Structure, Dynamics, Function, and Evolution.
    Grant Pearce F; Hudson AO; Loomes K; Dobson RCJ
    Subcell Biochem; 2017; 83():271-289. PubMed ID: 28271480
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.