BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

404 related articles for article (PubMed ID: 33592542)

  • 1. USP13 regulates the replication stress response by deubiquitinating TopBP1.
    Kim W; Zhao F; Gao H; Qin S; Hou J; Deng M; Kloeber JA; Huang J; Zhou Q; Guo G; Gao M; Zeng X; Zhu S; Tu X; Wu Z; Zhang Y; Yin P; Kaufmann SH; Luo K; Lou Z
    DNA Repair (Amst); 2021 Apr; 100():103063. PubMed ID: 33592542
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ATR activation is regulated by dimerization of ATR activating proteins.
    Thada V; Cortez D
    J Biol Chem; 2021; 296():100455. PubMed ID: 33636182
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer.
    Liu K; Graves JD; Lin FT; Lin WC
    J Biol Chem; 2021; 296():100382. PubMed ID: 33556369
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CK2 kinase-mediated PHF8 phosphorylation controls TopBP1 stability to regulate DNA replication.
    Feng H; Lu J; Song X; Thongkum A; Zhang F; Lou L; Reizes O; Almasan A; Gong Z
    Nucleic Acids Res; 2020 Nov; 48(19):10940-10952. PubMed ID: 33010150
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphorylation of the BRCA1 C terminus (BRCT) repeat inhibitor of hTERT (BRIT1) protein coordinates TopBP1 protein recruitment and amplifies ataxia telangiectasia-mutated and Rad3-related (ATR) Signaling.
    Zhang B; Wang E; Dai H; Shen J; Hsieh HJ; Lu X; Peng G
    J Biol Chem; 2014 Dec; 289(49):34284-95. PubMed ID: 25301947
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interaction between Rad9-Hus1-Rad1 and TopBP1 activates ATR-ATRIP and promotes TopBP1 recruitment to sites of UV-damage.
    Ohashi E; Takeishi Y; Ueda S; Tsurimoto T
    DNA Repair (Amst); 2014 Sep; 21():1-11. PubMed ID: 25091155
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TopBP1 and DNA polymerase alpha-mediated recruitment of the 9-1-1 complex to stalled replication forks: implications for a replication restart-based mechanism for ATR checkpoint activation.
    Yan S; Michael WM
    Cell Cycle; 2009 Sep; 8(18):2877-84. PubMed ID: 19652550
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control.
    Gong Z; Kim JE; Leung CC; Glover JN; Chen J
    Mol Cell; 2010 Feb; 37(3):438-46. PubMed ID: 20159562
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation.
    Liu S; Bekker-Jensen S; Mailand N; Lukas C; Bartek J; Lukas J
    Mol Cell Biol; 2006 Aug; 26(16):6056-64. PubMed ID: 16880517
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates.
    Egger T; Morano L; Blanchard MP; Basbous J; Constantinou A
    Cell Rep; 2024 Apr; 43(4):114064. PubMed ID: 38578830
    [TBL] [Abstract][Full Text] [Related]  

  • 11. USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response.
    Li Y; Luo K; Yin Y; Wu C; Deng M; Li L; Chen Y; Nowsheen S; Lou Z; Yuan J
    Nat Commun; 2017 Jun; 8():15752. PubMed ID: 28569838
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutant p53 perturbs DNA replication checkpoint control through TopBP1 and Treslin.
    Liu K; Lin FT; Graves JD; Lee YJ; Lin WC
    Proc Natl Acad Sci U S A; 2017 May; 114(19):E3766-E3775. PubMed ID: 28439015
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Direct role for the replication protein treslin (Ticrr) in the ATR kinase-mediated checkpoint response.
    Hassan BH; Lindsey-Boltz LA; Kemp MG; Sancar A
    J Biol Chem; 2013 Jun; 288(26):18903-10. PubMed ID: 23696651
    [TBL] [Abstract][Full Text] [Related]  

  • 14. STAT-5 Regulates Transcription of the Topoisomerase IIβ-Binding Protein 1 (TopBP1) Gene To Activate the ATR Pathway and Promote Human Papillomavirus Replication.
    Hong S; Cheng S; Iovane A; Laimins LA
    mBio; 2015 Dec; 6(6):e02006-15. PubMed ID: 26695634
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A divergent role of the SIRT1-TopBP1 axis in regulating metabolic checkpoint and DNA damage checkpoint.
    Liu T; Lin YH; Leng W; Jung SY; Zhang H; Deng M; Evans D; Li Y; Luo K; Qin B; Qin J; Yuan J; Lou Z
    Mol Cell; 2014 Dec; 56(5):681-95. PubMed ID: 25454945
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Treacle and TOPBP1 control replication stress response in the nucleolus.
    Velichko AK; Ovsyannikova N; Petrova NV; Luzhin AV; Vorobjeva M; Gavrikov AS; Mishin AS; Kireev II; Razin SV; Kantidze OL
    J Cell Biol; 2021 Aug; 220(8):. PubMed ID: 34100862
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RBMX is required for activation of ATR on repetitive DNAs to maintain genome stability.
    Zheng T; Zhou H; Li X; Peng D; Yang Y; Zeng Y; Liu H; Ren J; Zhao Y
    Cell Death Differ; 2020 Nov; 27(11):3162-3176. PubMed ID: 32494026
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA.
    Choi JH; Lindsey-Boltz LA; Sancar A
    Nucleic Acids Res; 2009 Apr; 37(5):1501-9. PubMed ID: 19139065
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1).
    Lindsey-Boltz LA; Sancar A
    J Biol Chem; 2011 Jun; 286(22):19229-36. PubMed ID: 21502314
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Quantitative phosphoproteomics reveals mitotic function of the ATR activator ETAA1.
    Bass TE; Cortez D
    J Cell Biol; 2019 Apr; 218(4):1235-1249. PubMed ID: 30755469
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.