These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

286 related articles for article (PubMed ID: 33595380)

  • 1. Novel test strategies for in vitro seizure liability assessment.
    Tukker AM; Westerink RHS
    Expert Opin Drug Metab Toxicol; 2021 Aug; 17(8):923-936. PubMed ID: 33595380
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Applicability of hiPSC-Derived Neuronal Cocultures and Rodent Primary Cortical Cultures for In Vitro Seizure Liability Assessment.
    Tukker AM; Wijnolts FMJ; de Groot A; Westerink RHS
    Toxicol Sci; 2020 Nov; 178(1):71-87. PubMed ID: 32866265
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Towards animal-free neurotoxicity screening: Applicability of hiPSC-derived neuronal models for in vitro seizure liability assessment.
    Tukker AM; Van Kleef RGDM; Wijnolts FMJ; De Groot A; Westerink RHS
    ALTEX; 2020; 37(1):121-135. PubMed ID: 31686111
    [TBL] [Abstract][Full Text] [Related]  

  • 4.
    Grainger AI; King MC; Nagel DA; Parri HR; Coleman MD; Hill EJ
    Front Neurosci; 2018; 12():590. PubMed ID: 30233290
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Do in vitro assays in rat primary neurons predict drug-induced seizure liability in humans?
    Kreir M; Van Deuren B; Versweyveld S; De Bondt A; Van den Wyngaert I; Van der Linde H; Lu HR; Teuns G; Gallacher DJ
    Toxicol Appl Pharmacol; 2018 May; 346():45-57. PubMed ID: 29596924
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In Vitro Screening for Seizure Liability Using Microelectrode Array Technology.
    Bradley JA; Luithardt HH; Metea MR; Strock CJ
    Toxicol Sci; 2018 May; 163(1):240-253. PubMed ID: 29432603
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparative study for the IMI2-NeuroDeRisk project on microelectrode arrays to derisk drug-induced seizure liability.
    Zhai J; Traebert M; Zimmermann K; Delaunois A; Royer L; Salvagiotto G; Carlson C; Lagrutta A
    J Pharmacol Toxicol Methods; 2023; 123():107297. PubMed ID: 37499956
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Raster plots machine learning to predict the seizure liability of drugs and to identify drugs.
    Matsuda N; Odawara A; Kinoshita K; Okamura A; Shirakawa T; Suzuki I
    Sci Rep; 2022 Feb; 12(1):2281. PubMed ID: 35145132
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An integrated approach for early in vitro seizure prediction utilizing hiPSC neurons and human ion channel assays.
    Rockley K; Roberts R; Jennings H; Jones K; Davis M; Levesque P; Morton M
    Toxicol Sci; 2023 Oct; 196(1):126-140. PubMed ID: 37632788
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Can We Panelize Seizure?
    Roberts R; Authier S; Mellon RD; Morton M; Suzuki I; Tjalkens RB; Valentin JP; Pierson JB
    Toxicol Sci; 2021 Jan; 179(1):3-13. PubMed ID: 33165543
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Principal Component Analysis to Distinguish Seizure Liability of Drugs in Human iPS Cell-Derived Neurons.
    Ishibashi Y; Odawara A; Kinoshita K; Okamura A; Shirakawa T; Suzuki I
    Toxicol Sci; 2021 Nov; 184(2):265-275. PubMed ID: 34570236
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High-Throughput Screening Assay for Detecting Drug-Induced Changes in Synchronized Neuronal Oscillations and Potential Seizure Risk Based on Ca
    Lu HR; Seo M; Kreir M; Tanaka T; Yamoto R; Altrocchi C; van Ammel K; Tekle F; Pham L; Yao X; Teisman A; Gallacher DJ
    Cells; 2023 Mar; 12(6):. PubMed ID: 36980298
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Approach to Neurotoxicity using Human iPSC Neurons: Consortium for Safety Assessment using Human iPS Cells.
    Shirakawa T; Suzuki I
    Curr Pharm Biotechnol; 2020; 21(9):780-786. PubMed ID: 31782362
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Method for MEA Data Analysis of Drug-treated Rat Primary Neurons and Human iPSC-derived Neurons to Evaluate the Risk of Drug-induced Seizures].
    Ojima A; Miyamoto N
    Yakugaku Zasshi; 2018; 138(6):823-828. PubMed ID: 29863054
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Innovative models for
    Rockley KL; Roberts RA; Morton MJ
    Toxicol Res (Camb); 2019 Nov; 8(6):784-788. PubMed ID: 32206299
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Is the forming of neuronal network activity in human-induced pluripotent stem cells important for the detection of drug-induced seizure risks?
    Kreir M; Floren W; Policarpo R; De Bondt A; Van den Wyngaert I; Teisman A; Gallacher DJ; Lu HR
    Eur J Pharmacol; 2022 Sep; 931():175189. PubMed ID: 35987255
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rapid and accurate assessment of seizure liability of drugs by using an optimal support vector machine method.
    Zhang H; Li W; Xie Y; Wang WJ; Li LL; Yang SY
    Toxicol In Vitro; 2011 Dec; 25(8):1848-54. PubMed ID: 21641989
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Evaluation methods for drug-induced seizure by microelectrode array recording using human iPS cell-derived neurons].
    Shirakawa T; Suzuki I
    Nihon Yakurigaku Zasshi; 2020; 155(5):284-288. PubMed ID: 32879165
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Verification of the seizure liability of compounds based on their in vitro functional activity in cultured rat cortical neurons and co-cultured human iPSC-derived neurons with astrocytes and in vivo extrapolation to cerebrospinal fluid concentration.
    Ishibashi Y; Nagafuku N; Kinoshita K; Okamura A; Shirakawa T; Suzuki I
    Toxicol Appl Pharmacol; 2023 Oct; 476():116675. PubMed ID: 37661062
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bundling arrows: improving translational CNS drug development by integrated PK/PD-metabolomics.
    van den Brink WJ; Hankemeier T; van der Graaf PH; de Lange ECM
    Expert Opin Drug Discov; 2018 Jun; 13(6):539-550. PubMed ID: 29519169
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.