BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 33596246)

  • 1. Downregulation of PAICS due to loss of chromosome 4q is associated with poor survival in stage III colorectal cancer.
    Kobayashi Y; Kumamoto K; Okayama H; Matsumoto T; Nakano H; Saito K; Matsumoto Y; Endo E; Kanke Y; Watanabe Y; Onozawa H; Fujita S; Sakamoto W; Saito M; Momma T; Takenoshita S; Kono K
    PLoS One; 2021; 16(2):e0247169. PubMed ID: 33596246
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression and Role of PAICS, a De Novo Purine Biosynthetic Gene in Prostate Cancer.
    Chakravarthi BV; Goswami MT; Pathi SS; Dodson M; Chandrashekar DS; Agarwal S; Nepal S; Hodigere Balasubramanya SA; Siddiqui J; Lonigro RJ; Chinnaiyan AM; Kunju LP; Palanisamy N; Varambally S
    Prostate; 2017 Jan; 77(1):10-21. PubMed ID: 27550065
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer.
    Goswami MT; Chen G; Chakravarthi BV; Pathi SS; Anand SK; Carskadon SL; Giordano TJ; Chinnaiyan AM; Thomas DG; Palanisamy N; Beer DG; Varambally S
    Oncotarget; 2015 Sep; 6(27):23445-61. PubMed ID: 26140362
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer.
    Agarwal S; Chakravarthi BVSK; Behring M; Kim HG; Chandrashekar DS; Gupta N; Bajpai P; Elkholy A; Balasubramanya SAH; Hardy C; Diffalha SA; Varambally S; Manne U
    Cancers (Basel); 2020 Mar; 12(4):. PubMed ID: 32218208
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PAICS contributes to gastric carcinogenesis and participates in DNA damage response by interacting with histone deacetylase 1/2.
    Huang N; Xu C; Deng L; Li X; Bian Z; Zhang Y; Long S; Chen Y; Zhen N; Li G; Sun F
    Cell Death Dis; 2020 Jul; 11(7):507. PubMed ID: 32632107
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer Progression.
    Chakravarthi BVSK; Rodriguez Pena MDC; Agarwal S; Chandrashekar DS; Hodigere Balasubramanya SA; Jabboure FJ; Matoso A; Bivalacqua TJ; Rezaei K; Chaux A; Grizzle WE; Sonpavde G; Gordetsky J; Netto GJ; Varambally S
    Neoplasia; 2018 Sep; 20(9):894-904. PubMed ID: 30121007
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines.
    Meng M; Chen Y; Jia J; Li L; Yang S
    Biol Res; 2018 Aug; 51(1):24. PubMed ID: 30097015
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target.
    Škerlová J; Unterlass J; Göttmann M; Marttila P; Homan E; Helleday T; Jemth AS; Stenmark P
    J Biol Chem; 2020 Aug; 295(33):11656-11668. PubMed ID: 32571877
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development.
    Ng A; Uribe RA; Yieh L; Nuckels R; Gross JM
    Development; 2009 Aug; 136(15):2601-11. PubMed ID: 19570845
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome.
    Pelet A; Skopova V; Steuerwald U; Baresova V; Zarhrate M; Plaza JM; Hnizda A; Krijt M; Souckova O; Wibrand F; Andorsdóttir G; Joensen F; Sedlak D; Bleyer AJ; Kmoch S; Lyonnet S; Zikanova M
    Hum Mol Genet; 2019 Nov; 28(22):3805-3814. PubMed ID: 31600779
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NDST4 is a novel candidate tumor suppressor gene at chromosome 4q26 and its genetic loss predicts adverse prognosis in colorectal cancer.
    Tzeng ST; Tsai MH; Chen CL; Lee JX; Jao TM; Yu SL; Yen SJ; Yang YC
    PLoS One; 2013; 8(6):e67040. PubMed ID: 23825612
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: cellular models of de novo purine biosynthesis deficiency disorders.
    Duval N; Luhrs K; Wilkinson TG; Baresova V; Skopova V; Kmoch S; Vacano GN; Zikanova M; Patterson D
    Mol Genet Metab; 2013 Mar; 108(3):178-189. PubMed ID: 23394948
    [TBL] [Abstract][Full Text] [Related]  

  • 13. KRT17 as a prognostic biomarker for stage II colorectal cancer.
    Ujiie D; Okayama H; Saito K; Ashizawa M; Thar Min AK; Endo E; Kase K; Yamada L; Kikuchi T; Hanayama H; Fujita S; Sakamoto W; Endo H; Saito M; Mimura K; Saze Z; Momma T; Ohki S; Kono K
    Carcinogenesis; 2020 Jul; 41(5):591-599. PubMed ID: 31754689
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Roles of highly expressed PAICS in lung adenocarcinoma.
    Zhou S; Yan Y; Chen X; Wang X; Zeng S; Qian L; Wei J; Yang X; Zhou Y; Gong Z; Xu Z
    Gene; 2019 Apr; 692():1-8. PubMed ID: 30641222
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression.
    Agarwal S; Chakravarthi BVSK; Kim HG; Gupta N; Hale K; Balasubramanya SAH; Oliver PG; Thomas DG; Eltoum IA; Buchsbaum DJ; Manne U; Varambally S
    Transl Oncol; 2020 Jul; 13(7):100776. PubMed ID: 32422575
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hypomethylation-associated up-regulation of TCF3 expression and recurrence in stage II and III colorectal cancer.
    Li C; Cai S; Wang X; Jiang Z
    PLoS One; 2014; 9(11):e112005. PubMed ID: 25375219
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification and characterization of ANO9 in stage II and III colorectal carcinoma.
    Li C; Cai S; Wang X; Jiang Z
    Oncotarget; 2015 Oct; 6(30):29324-34. PubMed ID: 26317553
    [TBL] [Abstract][Full Text] [Related]  

  • 18. UBR5 Contributes to Colorectal Cancer Progression by Destabilizing the Tumor Suppressor ECRG4.
    Wang J; Zhao X; Jin L; Wu G; Yang Y
    Dig Dis Sci; 2017 Oct; 62(10):2781-2789. PubMed ID: 28856538
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Multienzyme interactions of the de novo purine biosynthetic protein PAICS facilitate purinosome formation and metabolic channeling.
    He J; Zou LN; Pareek V; Benkovic SJ
    J Biol Chem; 2022 May; 298(5):101853. PubMed ID: 35331738
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RacGAP1 expression, increasing tumor malignant potential, as a predictive biomarker for lymph node metastasis and poor prognosis in colorectal cancer.
    Imaoka H; Toiyama Y; Saigusa S; Kawamura M; Kawamoto A; Okugawa Y; Hiro J; Tanaka K; Inoue Y; Mohri Y; Kusunoki M
    Carcinogenesis; 2015 Mar; 36(3):346-54. PubMed ID: 25568185
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.