BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

341 related articles for article (PubMed ID: 33596982)

  • 1. The emerging role of KDM5A in human cancer.
    Yang GJ; Zhu MH; Lu XJ; Liu YJ; Lu JF; Leung CH; Ma DL; Chen J
    J Hematol Oncol; 2021 Feb; 14(1):30. PubMed ID: 33596982
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacological inhibition of KDM5A for cancer treatment.
    Yang GJ; Wu J; Miao L; Zhu MH; Zhou QJ; Lu XJ; Lu JF; Leung CH; Ma DL; Chen J
    Eur J Med Chem; 2021 Dec; 226():113855. PubMed ID: 34555614
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The KDM5 family of histone demethylases as targets in oncology drug discovery.
    Rasmussen PB; Staller P
    Epigenomics; 2014 Jun; 6(3):277-86. PubMed ID: 25111482
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance.
    Gale M; Sayegh J; Cao J; Norcia M; Gareiss P; Hoyer D; Merkel JS; Yan Q
    Oncotarget; 2016 Jun; 7(26):39931-39944. PubMed ID: 27224921
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Domain architecture and protein-protein interactions regulate KDM5A recruitment to the chromatin.
    Kataria A; Tyagi S
    Epigenetics; 2023 Dec; 18(1):2268813. PubMed ID: 37838974
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy.
    Yang GJ; Wang W; Mok SWF; Wu C; Law BYK; Miao XM; Wu KJ; Zhong HJ; Wong CY; Wong VKW; Ma DL; Leung CH
    Angew Chem Int Ed Engl; 2018 Oct; 57(40):13091-13095. PubMed ID: 29968419
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.
    Horton JR; Engstrom A; Zoeller EL; Liu X; Shanks JR; Zhang X; Johns MA; Vertino PM; Fu H; Cheng X
    J Biol Chem; 2016 Feb; 291(6):2631-46. PubMed ID: 26645689
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Extended Recognition of the Histone H3 Tail by Histone Demethylase KDM5A.
    Petronikolou N; Longbotham JE; Fujimori DG
    Biochemistry; 2020 Feb; 59(5):647-651. PubMed ID: 31985200
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex.
    Nishibuchi G; Shibata Y; Hayakawa T; Hayakawa N; Ohtani Y; Sinmyozu K; Tagami H; Nakayama J
    J Biol Chem; 2014 Oct; 289(42):28956-70. PubMed ID: 25190814
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-based design and discovery of potent and selective KDM5 inhibitors.
    Nie Z; Shi L; Lai C; O'Connell SM; Xu J; Stansfield RK; Hosfield DJ; Veal JM; Stafford JA
    Bioorg Med Chem Lett; 2018 May; 28(9):1490-1494. PubMed ID: 29627262
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of in vitro JMJD lysine demethylase candidate substrates via systematic determination of substrate preference.
    Hoekstra M; Biggar KK
    Anal Biochem; 2021 Nov; 633():114429. PubMed ID: 34678252
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A.
    Chaturvedi CP; Somasundaram B; Singh K; Carpenedo RL; Stanford WL; Dilworth FJ; Brand M
    Proc Natl Acad Sci U S A; 2012 Nov; 109(46):18845-50. PubMed ID: 23112189
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Histone demethylase KDM5A is transactivated by the transcription factor C/EBPβ and promotes preadipocyte differentiation by inhibiting Wnt/β-catenin signaling.
    Guo L; Guo YY; Li BY; Peng WQ; Tang QQ
    J Biol Chem; 2019 Jun; 294(24):9642-9654. PubMed ID: 31061100
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis.
    Yoo J; Kim GW; Jeon YH; Kim JY; Lee SW; Kwon SH
    Exp Mol Med; 2022 Dec; 54(12):2107-2117. PubMed ID: 36509829
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds.
    Horton JR; Liu X; Gale M; Wu L; Shanks JR; Zhang X; Webber PJ; Bell JSK; Kales SC; Mott BT; Rai G; Jansen DJ; Henderson MJ; Urban DJ; Hall MD; Simeonov A; Maloney DJ; Johns MA; Fu H; Jadhav A; Vertino PM; Yan Q; Cheng X
    Cell Chem Biol; 2016 Jul; 23(7):769-781. PubMed ID: 27427228
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism.
    Torres IO; Kuchenbecker KM; Nnadi CI; Fletterick RJ; Kelly MJ; Fujimori DG
    Nat Commun; 2015 Feb; 6():6204. PubMed ID: 25686748
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis.
    Oser MG; Sabet AH; Gao W; Chakraborty AA; Schinzel AC; Jennings RB; Fonseca R; Bonal DM; Booker MA; Flaifel A; Novak JS; Christensen CL; Zhang H; Herbert ZT; Tolstorukov MY; Buss EJ; Wong KK; Bronson RT; Nguyen QD; Signoretti S; Kaelin WG
    Genes Dev; 2019 Dec; 33(23-24):1718-1738. PubMed ID: 31727771
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells.
    Vinogradova M; Gehling VS; Gustafson A; Arora S; Tindell CA; Wilson C; Williamson KE; Guler GD; Gangurde P; Manieri W; Busby J; Flynn EM; Lan F; Kim HJ; Odate S; Cochran AG; Liu Y; Wongchenko M; Yang Y; Cheung TK; Maile TM; Lau T; Costa M; Hegde GV; Jackson E; Pitti R; Arnott D; Bailey C; Bellon S; Cummings RT; Albrecht BK; Harmange JC; Kiefer JR; Trojer P; Classon M
    Nat Chem Biol; 2016 Jul; 12(7):531-8. PubMed ID: 27214401
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting histone demethylases KDM5A and KDM5B in AML cancer cells: A comparative view.
    Shokri G; Doudi S; Fathi-Roudsari M; Kouhkan F; Sanati MH
    Leuk Res; 2018 May; 68():105-111. PubMed ID: 29602065
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling.
    Longbotham JE; Chio CM; Dharmarajan V; Trnka MJ; Torres IO; Goswami D; Ruiz K; Burlingame AL; Griffin PR; Fujimori DG
    Nat Commun; 2019 Jan; 10(1):94. PubMed ID: 30626866
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.