341 related articles for article (PubMed ID: 33596982)
1. The emerging role of KDM5A in human cancer.
Yang GJ; Zhu MH; Lu XJ; Liu YJ; Lu JF; Leung CH; Ma DL; Chen J
J Hematol Oncol; 2021 Feb; 14(1):30. PubMed ID: 33596982
[TBL] [Abstract][Full Text] [Related]
2. Pharmacological inhibition of KDM5A for cancer treatment.
Yang GJ; Wu J; Miao L; Zhu MH; Zhou QJ; Lu XJ; Lu JF; Leung CH; Ma DL; Chen J
Eur J Med Chem; 2021 Dec; 226():113855. PubMed ID: 34555614
[TBL] [Abstract][Full Text] [Related]
3. The KDM5 family of histone demethylases as targets in oncology drug discovery.
Rasmussen PB; Staller P
Epigenomics; 2014 Jun; 6(3):277-86. PubMed ID: 25111482
[TBL] [Abstract][Full Text] [Related]
4. Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance.
Gale M; Sayegh J; Cao J; Norcia M; Gareiss P; Hoyer D; Merkel JS; Yan Q
Oncotarget; 2016 Jun; 7(26):39931-39944. PubMed ID: 27224921
[TBL] [Abstract][Full Text] [Related]
5. Domain architecture and protein-protein interactions regulate KDM5A recruitment to the chromatin.
Kataria A; Tyagi S
Epigenetics; 2023 Dec; 18(1):2268813. PubMed ID: 37838974
[TBL] [Abstract][Full Text] [Related]
6. Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy.
Yang GJ; Wang W; Mok SWF; Wu C; Law BYK; Miao XM; Wu KJ; Zhong HJ; Wong CY; Wong VKW; Ma DL; Leung CH
Angew Chem Int Ed Engl; 2018 Oct; 57(40):13091-13095. PubMed ID: 29968419
[TBL] [Abstract][Full Text] [Related]
7. Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.
Horton JR; Engstrom A; Zoeller EL; Liu X; Shanks JR; Zhang X; Johns MA; Vertino PM; Fu H; Cheng X
J Biol Chem; 2016 Feb; 291(6):2631-46. PubMed ID: 26645689
[TBL] [Abstract][Full Text] [Related]
8. Extended Recognition of the Histone H3 Tail by Histone Demethylase KDM5A.
Petronikolou N; Longbotham JE; Fujimori DG
Biochemistry; 2020 Feb; 59(5):647-651. PubMed ID: 31985200
[TBL] [Abstract][Full Text] [Related]
9. Physical and functional interactions between the histone H3K4 demethylase KDM5A and the nucleosome remodeling and deacetylase (NuRD) complex.
Nishibuchi G; Shibata Y; Hayakawa T; Hayakawa N; Ohtani Y; Sinmyozu K; Tagami H; Nakayama J
J Biol Chem; 2014 Oct; 289(42):28956-70. PubMed ID: 25190814
[TBL] [Abstract][Full Text] [Related]
10. Structure-based design and discovery of potent and selective KDM5 inhibitors.
Nie Z; Shi L; Lai C; O'Connell SM; Xu J; Stansfield RK; Hosfield DJ; Veal JM; Stafford JA
Bioorg Med Chem Lett; 2018 May; 28(9):1490-1494. PubMed ID: 29627262
[TBL] [Abstract][Full Text] [Related]
11. Identification of in vitro JMJD lysine demethylase candidate substrates via systematic determination of substrate preference.
Hoekstra M; Biggar KK
Anal Biochem; 2021 Nov; 633():114429. PubMed ID: 34678252
[TBL] [Abstract][Full Text] [Related]
12. Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A.
Chaturvedi CP; Somasundaram B; Singh K; Carpenedo RL; Stanford WL; Dilworth FJ; Brand M
Proc Natl Acad Sci U S A; 2012 Nov; 109(46):18845-50. PubMed ID: 23112189
[TBL] [Abstract][Full Text] [Related]
13. Histone demethylase KDM5A is transactivated by the transcription factor C/EBPβ and promotes preadipocyte differentiation by inhibiting Wnt/β-catenin signaling.
Guo L; Guo YY; Li BY; Peng WQ; Tang QQ
J Biol Chem; 2019 Jun; 294(24):9642-9654. PubMed ID: 31061100
[TBL] [Abstract][Full Text] [Related]
14. Drawing a line between histone demethylase KDM5A and KDM5B: their roles in development and tumorigenesis.
Yoo J; Kim GW; Jeon YH; Kim JY; Lee SW; Kwon SH
Exp Mol Med; 2022 Dec; 54(12):2107-2117. PubMed ID: 36509829
[TBL] [Abstract][Full Text] [Related]
15. Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds.
Horton JR; Liu X; Gale M; Wu L; Shanks JR; Zhang X; Webber PJ; Bell JSK; Kales SC; Mott BT; Rai G; Jansen DJ; Henderson MJ; Urban DJ; Hall MD; Simeonov A; Maloney DJ; Johns MA; Fu H; Jadhav A; Vertino PM; Yan Q; Cheng X
Cell Chem Biol; 2016 Jul; 23(7):769-781. PubMed ID: 27427228
[TBL] [Abstract][Full Text] [Related]
16. Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism.
Torres IO; Kuchenbecker KM; Nnadi CI; Fletterick RJ; Kelly MJ; Fujimori DG
Nat Commun; 2015 Feb; 6():6204. PubMed ID: 25686748
[TBL] [Abstract][Full Text] [Related]
17. The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis.
Oser MG; Sabet AH; Gao W; Chakraborty AA; Schinzel AC; Jennings RB; Fonseca R; Bonal DM; Booker MA; Flaifel A; Novak JS; Christensen CL; Zhang H; Herbert ZT; Tolstorukov MY; Buss EJ; Wong KK; Bronson RT; Nguyen QD; Signoretti S; Kaelin WG
Genes Dev; 2019 Dec; 33(23-24):1718-1738. PubMed ID: 31727771
[TBL] [Abstract][Full Text] [Related]
18. An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells.
Vinogradova M; Gehling VS; Gustafson A; Arora S; Tindell CA; Wilson C; Williamson KE; Guler GD; Gangurde P; Manieri W; Busby J; Flynn EM; Lan F; Kim HJ; Odate S; Cochran AG; Liu Y; Wongchenko M; Yang Y; Cheung TK; Maile TM; Lau T; Costa M; Hegde GV; Jackson E; Pitti R; Arnott D; Bailey C; Bellon S; Cummings RT; Albrecht BK; Harmange JC; Kiefer JR; Trojer P; Classon M
Nat Chem Biol; 2016 Jul; 12(7):531-8. PubMed ID: 27214401
[TBL] [Abstract][Full Text] [Related]
19. Targeting histone demethylases KDM5A and KDM5B in AML cancer cells: A comparative view.
Shokri G; Doudi S; Fathi-Roudsari M; Kouhkan F; Sanati MH
Leuk Res; 2018 May; 68():105-111. PubMed ID: 29602065
[TBL] [Abstract][Full Text] [Related]
20. Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling.
Longbotham JE; Chio CM; Dharmarajan V; Trnka MJ; Torres IO; Goswami D; Ruiz K; Burlingame AL; Griffin PR; Fujimori DG
Nat Commun; 2019 Jan; 10(1):94. PubMed ID: 30626866
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]