These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 33604571)

  • 21. Small, Seeding-Competent Huntingtin Fibrils Are Prominent Aggregate Species in Brains of zQ175 Huntington's Disease Knock-in Mice.
    Schindler F; Praedel N; Neuendorf N; Kunz S; Schnoegl S; Mason MA; Taxy BA; Bates GP; Khoshnan A; Priller J; Grimm J; Maier M; Boeddrich A; Wanker EE
    Front Neurosci; 2021; 15():682172. PubMed ID: 34239412
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease.
    Reddy PH; Charles V; Williams M; Miller G; Whetsell WO; Tagle DA
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun; 354(1386):1035-45. PubMed ID: 10434303
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Phosphorodiamidate morpholino oligomers suppress mutant huntingtin expression and attenuate neurotoxicity.
    Sun X; Marque LO; Cordner Z; Pruitt JL; Bhat M; Li PP; Kannan G; Ladenheim EE; Moran TH; Margolis RL; Rudnicki DD
    Hum Mol Genet; 2014 Dec; 23(23):6302-17. PubMed ID: 25035419
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Increased Steady-State Mutant Huntingtin mRNA in Huntington's Disease Brain.
    Liu W; Chaurette J; Pfister EL; Kennington LA; Chase KO; Bullock J; Vonsattel JP; Faull RL; Macdonald D; DiFiglia M; Zamore PD; Aronin N
    J Huntingtons Dis; 2013; 2(4):491-500. PubMed ID: 25062733
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Anti-PolyQ Antibodies Recognize a Short PolyQ Stretch in Both Normal and Mutant Huntingtin Exon 1.
    Owens GE; New DM; West AP; Bjorkman PJ
    J Mol Biol; 2015 Jul; 427(15):2507-2519. PubMed ID: 26047735
    [TBL] [Abstract][Full Text] [Related]  

  • 26.
    McLean ZL; Gao D; Correia K; Roy JCL; Shibata S; Farnum IN; Valdepenas-Mellor Z; Rapuru M; Morini E; Ruliera J; Gillis T; Lucente D; Kleinstiver BP; Lee JM; MacDonald ME; Wheeler VC; Pinto RM; Gusella JF
    bioRxiv; 2023 Jul; ():. PubMed ID: 37547003
    [TBL] [Abstract][Full Text] [Related]  

  • 27. DMSO and glycerol reduce bacterial death induced by expression of truncated N-terminal huntingtin with expanded polyglutamine tracts.
    Nagao Y; Ishiguro H; Nukina N
    Biochim Biophys Acta; 2000 Oct; 1502(2):247-56. PubMed ID: 11040449
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
    Loupe JM; Pinto RM; Kim KH; Gillis T; Mysore JS; Andrew MA; Kovalenko M; Murtha R; Seong I; Gusella JF; Kwak S; Howland D; Lee R; Lee JM; Wheeler VC; MacDonald ME
    Hum Mol Genet; 2020 Nov; 29(18):3044-3053. PubMed ID: 32876667
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Formation of polyglutamine inclusions in a wide range of non-CNS tissues in the HdhQ150 knock-in mouse model of Huntington's disease.
    Moffitt H; McPhail GD; Woodman B; Hobbs C; Bates GP
    PLoS One; 2009 Nov; 4(11):e8025. PubMed ID: 19956633
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington's disease.
    Choi DE; Shin JW; Zeng S; Hong EP; Jang JH; Loupe JM; Wheeler VC; Stutzman HE; Kleinstiver BP; Lee JM
    bioRxiv; 2023 Apr; ():. PubMed ID: 37162872
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Amyloid formation by mutant huntingtin: threshold, progressivity and recruitment of normal polyglutamine proteins.
    Huang CC; Faber PW; Persichetti F; Mittal V; Vonsattel JP; MacDonald ME; Gusella JF
    Somat Cell Mol Genet; 1998 Jul; 24(4):217-33. PubMed ID: 10410676
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Biodegradable delivery system containing a peptide inhibitor of polyglutamine aggregation: a step toward therapeutic development in Huntington's disease.
    Joshi AS; Thakur AK
    J Pept Sci; 2014 Aug; 20(8):630-9. PubMed ID: 24788406
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse.
    Wheeler VC; Auerbach W; White JK; Srinidhi J; Auerbach A; Ryan A; Duyao MP; Vrbanac V; Weaver M; Gusella JF; Joyner AL; MacDonald ME
    Hum Mol Genet; 1999 Jan; 8(1):115-22. PubMed ID: 9887339
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Longitudinal behavioral, cross-sectional transcriptional and histopathological characterization of a knock-in mouse model of Huntington's disease with 140 CAG repeats.
    Rising AC; Xu J; Carlson A; Napoli VV; Denovan-Wright EM; Mandel RJ
    Exp Neurol; 2011 Apr; 228(2):173-82. PubMed ID: 21192926
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene.
    Ishiguro H; Yamada K; Sawada H; Nishii K; Ichino N; Sawada M; Kurosawa Y; Matsushita N; Kobayashi K; Goto J; Hashida H; Masuda N; Kanazawa I; Nagatsu T
    J Neurosci Res; 2001 Aug; 65(4):289-97. PubMed ID: 11494364
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Quantification of age-dependent somatic CAG repeat instability in Hdh CAG knock-in mice reveals different expansion dynamics in striatum and liver.
    Lee JM; Pinto RM; Gillis T; St Claire JC; Wheeler VC
    PLoS One; 2011; 6(8):e23647. PubMed ID: 21897851
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Expanded CAG repeats in the murine Huntington's disease gene increases neuronal differentiation of embryonic and neural stem cells.
    Lorincz MT; Zawistowski VA
    Mol Cell Neurosci; 2009 Jan; 40(1):1-13. PubMed ID: 18625318
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Precise Excision of the CAG Tract from the Huntingtin Gene by Cas9 Nickases.
    Dabrowska M; Juzwa W; Krzyzosiak WJ; Olejniczak M
    Front Neurosci; 2018; 12():75. PubMed ID: 29535594
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Allele-specific quantitation of ATXN3 and HTT transcripts in polyQ disease models.
    Joachimiak P; Ciesiołka A; Kozłowska E; Świtoński PM; Figura G; Ciołak A; Adamek G; Surdyka M; Kalinowska-Pośka Ż; Figiel M; Caron NS; Hayden MR; Fiszer A
    BMC Biol; 2023 Feb; 21(1):17. PubMed ID: 36726088
    [TBL] [Abstract][Full Text] [Related]  

  • 40. HD CAG-correlated gene expression changes support a simple dominant gain of function.
    Jacobsen JC; Gregory GC; Woda JM; Thompson MN; Coser KR; Murthy V; Kohane IS; Gusella JF; Seong IS; MacDonald ME; Shioda T; Lee JM
    Hum Mol Genet; 2011 Jul; 20(14):2846-60. PubMed ID: 21536587
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.