BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 33608498)

  • 1. Positive feedback of SuFu negating protein 1 on Hedgehog signaling promotes colorectal tumor growth.
    Yan Z; Cheng M; Hu G; Wang Y; Zeng S; Huang A; Xu L; Liu Y; Shi C; Deng L; Lu Q; Rao H; Lu H; Chen YG; Luo S
    Cell Death Dis; 2021 Feb; 12(2):199. PubMed ID: 33608498
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation.
    Yang J; Wang J; Liu Y; Zhang Y; Huang W; Zou Y; Qiu Y; Cai W; Gao J; Zhou H; Wu Y; Liu W; Ding Q; Zhang Y; Yin PH; Tan W
    Cell Death Dis; 2021 Jul; 12(7):707. PubMed ID: 34267186
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved.
    Chen MH; Wilson CW; Li YJ; Law KK; Lu CS; Gacayan R; Zhang X; Hui CC; Chuang PT
    Genes Dev; 2009 Aug; 23(16):1910-28. PubMed ID: 19684112
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nek2A/SuFu feedback loop regulates Gli-mediated Hedgehog signaling pathway.
    Zhou F; Huang D; Li Y; Hu G; Rao H; Lu Q; Luo S; Wang Y
    Int J Oncol; 2017 Feb; 50(2):373-380. PubMed ID: 28035348
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nek2A phosphorylates and stabilizes SuFu: A new strategy of Gli2/Hedgehog signaling regulatory mechanism.
    Wang Y; Li Y; Hu G; Huang X; Rao H; Xiong X; Luo Z; Lu Q; Luo S
    Cell Signal; 2016 Sep; 28(9):1304-1313. PubMed ID: 27297360
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development.
    Raducu M; Fung E; Serres S; Infante P; Barberis A; Fischer R; Bristow C; Thézénas ML; Finta C; Christianson JC; Buffa FM; Kessler BM; Sibson NR; Di Marcotullio L; Toftgård R; D'Angiolella V
    EMBO J; 2016 Jul; 35(13):1400-16. PubMed ID: 27234298
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development.
    Lin C; Chen MH; Yao E; Song H; Gacayan R; Hui CC; Chuang PT
    Dev Biol; 2014 Aug; 392(2):324-33. PubMed ID: 24886827
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Silencing speckle-type POZ protein by promoter hypermethylation decreases cell apoptosis through upregulating Hedgehog signaling pathway in colorectal cancer.
    Zhi X; Tao J; Zhang L; Tao R; Ma L; Qin J
    Cell Death Dis; 2016 Dec; 7(12):e2569. PubMed ID: 28032859
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.
    Infante P; Faedda R; Bernardi F; Bufalieri F; Lospinoso Severini L; Alfonsi R; Mazzà D; Siler M; Coni S; Po A; Petroni M; Ferretti E; Mori M; De Smaele E; Canettieri G; Capalbo C; Maroder M; Screpanti I; Kool M; Pfister SM; Guardavaccaro D; Gulino A; Di Marcotullio L
    Nat Commun; 2018 Mar; 9(1):976. PubMed ID: 29515120
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Hedgehog signaling pathway promotes chemotherapy resistance via multidrug resistance protein 1 in ovarian cancer.
    Zhang H; Hu L; Cheng M; Wang Q; Hu X; Chen Q
    Oncol Rep; 2020 Dec; 44(6):2610-2620. PubMed ID: 33125122
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis.
    Coquenlorge S; Yin WC; Yung T; Pan J; Zhang X; Mo R; Belik J; Hui CC; Kim TH
    Cell Rep; 2019 Jun; 27(10):3006-3018.e4. PubMed ID: 31167144
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling.
    Lin C; Yao E; Wang K; Nozawa Y; Shimizu H; Johnson JR; Chen JN; Krogan NJ; Chuang PT
    Genes Dev; 2014 Nov; 28(22):2547-63. PubMed ID: 25403183
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hedgehog signaling promotes the degradation of tumor suppressor Sufu through the ubiquitin-proteasome pathway.
    Yue S; Chen Y; Cheng SY
    Oncogene; 2009 Jan; 28(4):492-9. PubMed ID: 18997815
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Suppressor of fused controls cerebellum granule cell proliferation by suppressing Fgf8 and spatially regulating Gli proteins.
    Jiwani T; Kim JJ; Rosenblum ND
    Development; 2020 Feb; 147(3):. PubMed ID: 31932349
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ubiquitin ligase TRIM65 promotes colorectal cancer metastasis by targeting ARHGAP35 for protein degradation.
    Chen D; Li Y; Zhang X; Wu H; Wang Q; Cai J; Cui Y; Liu H; Lan P; Wang J; Yang Z; Wang L
    Oncogene; 2019 Sep; 38(37):6429-6444. PubMed ID: 31332286
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
    Zhang Y; Fu L; Qi X; Zhang Z; Xia Y; Jia J; Jiang J; Zhao Y; Wu G
    Nat Commun; 2013; 4():2608. PubMed ID: 24217340
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nuclear receptor coactivator SRC-1 promotes colorectal cancer progression through enhancing GLI2-mediated Hedgehog signaling.
    Guo P; Chen Q; Peng K; Xie J; Liu J; Ren W; Tong Z; Li M; Xu J; Zhang Y; Yu C; Mo P
    Oncogene; 2022 May; 41(20):2846-2859. PubMed ID: 35418691
    [TBL] [Abstract][Full Text] [Related]  

  • 18. UBR5 Contributes to Colorectal Cancer Progression by Destabilizing the Tumor Suppressor ECRG4.
    Wang J; Zhao X; Jin L; Wu G; Yang Y
    Dig Dis Sci; 2017 Oct; 62(10):2781-2789. PubMed ID: 28856538
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proteasome inhibitor induced SIRT1 deacetylates GLI2 to enhance hedgehog signaling activity and drug resistance in multiple myeloma.
    Xie Y; Liu J; Jiang H; Wang J; Li X; Wang J; Zhu S; Guo J; Li T; Zhong Y; Zhang Q; Liu Z
    Oncogene; 2020 Jan; 39(4):922-934. PubMed ID: 31576013
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Gli as a novel therapeutic target in malignant pleural mesothelioma.
    Li H; Lui N; Cheng T; Tseng HH; Yue D; Giroux-Leprieur E; Do HT; Sheng Q; Jin JQ; Luh TW; Jablons DM; He B
    PLoS One; 2013; 8(3):e57346. PubMed ID: 23483902
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.