BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

376 related articles for article (PubMed ID: 33615359)

  • 1. Protective effects of antidepressant citalopram against abnormal APP processing and amyloid beta-induced mitochondrial dynamics, biogenesis, mitophagy and synaptic toxicities in Alzheimer's disease.
    Reddy AP; Yin X; Sawant N; Reddy PH
    Hum Mol Genet; 2021 May; 30(10):847-864. PubMed ID: 33615359
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective serotonin reuptake inhibitor citalopram ameliorates cognitive decline and protects against amyloid beta-induced mitochondrial dynamics, biogenesis, autophagy, mitophagy and synaptic toxicities in a mouse model of Alzheimer's disease.
    Reddy AP; Sawant N; Morton H; Kshirsagar S; Bunquin LE; Yin X; Reddy PH
    Hum Mol Genet; 2021 May; 30(9):789-810. PubMed ID: 33791799
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease.
    Reddy PH; Yin X; Manczak M; Kumar S; Pradeepkiran JA; Vijayan M; Reddy AP
    Hum Mol Genet; 2018 Jul; 27(14):2502-2516. PubMed ID: 29701781
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protective effects of mitophagy enhancers against amyloid beta-induced mitochondrial and synaptic toxicities in Alzheimer disease.
    Kshirsagar S; Sawant N; Morton H; Reddy AP; Reddy PH
    Hum Mol Genet; 2022 Feb; 31(3):423-439. PubMed ID: 34505123
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
    Manczak M; Kandimalla R; Fry D; Sesaki H; Reddy PH
    Hum Mol Genet; 2016 Dec; 25(23):5148-5166. PubMed ID: 27677309
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer's disease.
    Manczak M; Kandimalla R; Yin X; Reddy PH
    Hum Mol Genet; 2018 Apr; 27(8):1332-1342. PubMed ID: 29408999
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mitophagy enhancers against phosphorylated Tau-induced mitochondrial and synaptic toxicities in Alzheimer disease.
    Kshirsagar S; Sawant N; Morton H; Reddy AP; Reddy PH
    Pharmacol Res; 2021 Dec; 174():105973. PubMed ID: 34763094
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rlip overexpression reduces oxidative stress and mitochondrial dysfunction in Alzheimer's disease: Mechanistic insights.
    Reddy PH; Kshirsagar S; Bose C; Pradeepkiran JA; Hindle A; Singh SP; Reddy AP
    Biochim Biophys Acta Mol Basis Dis; 2023 Oct; 1869(7):166759. PubMed ID: 37225106
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protective effects of a natural product, curcumin, against amyloid β induced mitochondrial and synaptic toxicities in Alzheimer's disease.
    Reddy PH; Manczak M; Yin X; Grady MC; Mitchell A; Kandimalla R; Kuruva CS
    J Investig Med; 2016 Dec; 64(8):1220-1234. PubMed ID: 27521081
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel MicroRNA-455-3p and its protective effects against abnormal APP processing and amyloid beta toxicity in Alzheimer's disease.
    Kumar S; Reddy AP; Yin X; Reddy PH
    Biochim Biophys Acta Mol Basis Dis; 2019 Sep; 1865(9):2428-2440. PubMed ID: 31181293
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitochondria-targeted small molecule SS31: a potential candidate for the treatment of Alzheimer's disease.
    Reddy PH; Manczak M; Kandimalla R
    Hum Mol Genet; 2017 Apr; 26(8):1483-1496. PubMed ID: 28186562
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protective effects of a small molecule inhibitor, DDQ against amyloid beta in Alzheimer's disease.
    Vijayan M; Bose C; Reddy PH
    Mitochondrion; 2021 Jul; 59():17-29. PubMed ID: 33839321
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aqua-soluble DDQ reduces the levels of Drp1 and Aβ and inhibits abnormal interactions between Aβ and Drp1 and protects Alzheimer's disease neurons from Aβ- and Drp1-induced mitochondrial and synaptic toxicities.
    Kuruva CS; Manczak M; Yin X; Ogunmokun G; Reddy AP; Reddy PH
    Hum Mol Genet; 2017 Sep; 26(17):3375-3395. PubMed ID: 28854701
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protective effects of SSRI, Citalopram in mutant APP and mutant Tau expressed dorsal raphe neurons in Alzheimer's disease.
    Sawant N; Kshirsagar S; Reddy PH; Reddy AP
    Biochim Biophys Acta Mol Basis Dis; 2024 Feb; 1870(2):166942. PubMed ID: 37931714
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimer's Disease.
    Reddy PH; Oliver DM
    Cells; 2019 May; 8(5):. PubMed ID: 31121890
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protective effects of BACE1 inhibitory ligand molecules against amyloid beta-induced synaptic and mitochondrial toxicities in Alzheimer's disease.
    Pradeepkiran JA; Reddy AP; Yin X; Manczak M; Reddy PH
    Hum Mol Genet; 2020 Jan; 29(1):49-69. PubMed ID: 31595293
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Honokiol improves cognitive impairment in APP/PS1 mice through activating mitophagy and mitochondrial unfolded protein response.
    Hou M; Bao W; Gao Y; Chen J; Song G
    Chem Biol Interact; 2022 Jan; 351():109741. PubMed ID: 34752757
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reduced dynamin-related protein 1 protects against phosphorylated Tau-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.
    Kandimalla R; Manczak M; Fry D; Suneetha Y; Sesaki H; Reddy PH
    Hum Mol Genet; 2016 Nov; 25(22):4881-4897. PubMed ID: 28173111
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Citalopram restores short-term memory deficit and non-cognitive behaviors in APP/PS1 mice while halting the advance of Alzheimer's disease-like pathology.
    Zhang Q; Yang C; Liu T; Liu L; Li F; Cai Y; Lv K; Li X; Gao J; Sun D; Xu H; Yang Q; Fan X
    Neuropharmacology; 2018 Mar; 131():475-486. PubMed ID: 29241655
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondria-Division Inhibitor 1 Protects Against Amyloid-β induced Mitochondrial Fragmentation and Synaptic Damage in Alzheimer's Disease.
    Reddy PH; Manczak M; Yin X
    J Alzheimers Dis; 2017; 58(1):147-162. PubMed ID: 28409745
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.