BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 33621210)

  • 1. Constitutive activation of WASp leads to abnormal cytotoxic cells with increased granzyme B and degranulation response to target cells.
    Kritikou JS; Oliveira MM; Record J; Saeed MB; Nigam SM; He M; Keszei M; Wagner AK; Brauner H; Sendel A; Sedimbi SK; Rentouli S; Lane DP; Snapper SB; Kärre K; Vandenberghe P; Orange JS; Westerberg LS
    JCI Insight; 2021 Mar; 6(6):. PubMed ID: 33621210
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes.
    Zhang J; Shehabeldin A; da Cruz LA; Butler J; Somani AK; McGavin M; Kozieradzki I; dos Santos AO; Nagy A; Grinstein S; Penninger JM; Siminovitch KA
    J Exp Med; 1999 Nov; 190(9):1329-42. PubMed ID: 10544204
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Wiskott-Aldrich syndrome protein may be critical for CD8
    Li S; Huang J; Zhang YL; Zhu Y; An YF; Du J; Zhang ZL; Xia Y; Liu L; Wang L; Luo XH
    Cell Immunol; 2019 Apr; 338():43-50. PubMed ID: 30981413
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IL-2 in the tumor microenvironment is necessary for Wiskott-Aldrich syndrome protein deficient NK cells to respond to tumors in vivo.
    Kritikou JS; Dahlberg CI; Baptista MA; Wagner AK; Banerjee PP; Gwalani LA; Poli C; Panda SK; Kärre K; Kaech SM; Wermeling F; Andersson J; Orange JS; Brauner H; Westerberg LS
    Sci Rep; 2016 Aug; 6():30636. PubMed ID: 27477778
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Constitutive activation of WASp in X-linked neutropenia renders neutrophils hyperactive.
    Keszei M; Record J; Kritikou JS; Wurzer H; Geyer C; Thiemann M; Drescher P; Brauner H; Köcher L; James J; He M; Baptista MA; Dahlberg CI; Biswas A; Lane DP; Song W; Pütsep K; Vandenberghe P; Snapper SB; Westerberg LS
    J Clin Invest; 2018 Aug; 128(9):4115-4131. PubMed ID: 30124469
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Controlled WASp activity regulates the proliferative response for Treg cell differentiation in the thymus.
    Vasconcelos-Fontes L; Vieira RC; He M; Ferreira-Reis R; Jurberg AD; Arêas Mendes-da-Cruz D; Andersson J; Cotta-de-Almeida V; Westerberg LS
    Eur J Immunol; 2024 May; 54(5):e2350450. PubMed ID: 38356202
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes.
    Westerberg LS; Meelu P; Baptista M; Eston MA; Adamovich DA; Cotta-de-Almeida V; Seed B; Rosen MK; Vandenberghe P; Thrasher AJ; Klein C; Alt FW; Snapper SB
    J Exp Med; 2010 Jun; 207(6):1145-52. PubMed ID: 20513746
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations of the Wiskott-Aldrich Syndrome Protein affect protein expression and dictate the clinical phenotypes.
    Ochs HD
    Immunol Res; 2009; 44(1-3):84-8. PubMed ID: 19082760
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Wiskott-Aldrich syndrome: The actin cytoskeleton and immune cell function.
    Blundell MP; Worth A; Bouma G; Thrasher AJ
    Dis Markers; 2010; 29(3-4):157-75. PubMed ID: 21178275
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The open conformation of WASP regulates its nuclear localization and gene transcription in myeloid cells.
    Looi CY; Sasahara Y; Watanabe Y; Satoh M; Hakozaki I; Uchiyama M; Wong WF; Du W; Uchiyama T; Kumaki S; Tsuchiya S; Kure S
    Int Immunol; 2014 Jun; 26(6):341-52. PubMed ID: 24402308
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A peptide derived from the Wiskott-Aldrich syndrome (WAS) protein-interacting protein (WIP) restores WAS protein level and actin cytoskeleton reorganization in lymphocytes from patients with WAS mutations that disrupt WIP binding.
    Massaad MJ; Ramesh N; Le Bras S; Giliani S; Notarangelo LD; Al-Herz W; Notarangelo LD; Geha RS
    J Allergy Clin Immunol; 2011 Apr; 127(4):998-1005.e1-2. PubMed ID: 21376381
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses.
    Orange JS; Ramesh N; Remold-O'Donnell E; Sasahara Y; Koopman L; Byrne M; Bonilla FA; Rosen FS; Geha RS; Strominger JL
    Proc Natl Acad Sci U S A; 2002 Aug; 99(17):11351-6. PubMed ID: 12177428
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Impaired NK-cell migration in WAS/XLT patients: role of Cdc42/WASp pathway in the control of chemokine-induced beta2 integrin high-affinity state.
    Stabile H; Carlino C; Mazza C; Giliani S; Morrone S; Notarangelo LD; Notarangelo LD; Santoni A; Gismondi A
    Blood; 2010 Apr; 115(14):2818-26. PubMed ID: 20130240
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Molecular pathogenesis of Wiskott-Aldrich syndrome].
    Sasahara Y; Tsuchiya S
    Nihon Rinsho Meneki Gakkai Kaishi; 2005 Jun; 28(3):140-7. PubMed ID: 15997177
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Wiskott-Aldrich syndrome protein regulates nuclear translocation of NFAT2 and NF-kappa B (RelA) independently of its role in filamentous actin polymerization and actin cytoskeletal rearrangement.
    Huang W; Ochs HD; Dupont B; Vyas YM
    J Immunol; 2005 Mar; 174(5):2602-11. PubMed ID: 15728466
    [TBL] [Abstract][Full Text] [Related]  

  • 16. IL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function.
    Orange JS; Roy-Ghanta S; Mace EM; Maru S; Rak GD; Sanborn KB; Fasth A; Saltzman R; Paisley A; Monaco-Shawver L; Banerjee PP; Pandey R
    J Clin Invest; 2011 Apr; 121(4):1535-48. PubMed ID: 21383498
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of WASp in T cells and B cells.
    Sun X; Wei Y; Lee PP; Ren B; Liu C
    Cell Immunol; 2019 Jul; 341():103919. PubMed ID: 31047647
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation.
    Snapper SB; Rosen FS; Mizoguchi E; Cohen P; Khan W; Liu CH; Hagemann TL; Kwan SP; Ferrini R; Davidson L; Bhan AK; Alt FW
    Immunity; 1998 Jul; 9(1):81-91. PubMed ID: 9697838
    [TBL] [Abstract][Full Text] [Related]  

  • 19. T-cell receptor ligation causes Wiskott-Aldrich syndrome protein degradation and F-actin assembly downregulation.
    Watanabe Y; Sasahara Y; Ramesh N; Massaad MJ; Yeng Looi C; Kumaki S; Kure S; Geha RS; Tsuchiya S
    J Allergy Clin Immunol; 2013 Sep; 132(3):648-655.e1. PubMed ID: 23684068
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation.
    He M; Saeed MB; Record J; Keszei M; Gonçalves Pinho L; Vasconcelos-Fontes L; D'Aulerio R; Vieira R; Oliveira MMS; Geyer C; Bohaumilitzky L; Thiemann M; Deordieva E; Buedts L; Matias Lopes JP; Pershin D; Hammarström L; Xia Y; Zhao X; Cunningham-Rundles C; Thrasher AJ; Burns SO; Cotta-de-Almeida V; Liu C; Shcherbina A; Vandenberghe P; Westerberg LS
    J Allergy Clin Immunol; 2022 Mar; 149(3):1069-1084. PubMed ID: 34384840
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.