BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 33622270)

  • 1. High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability.
    Matson DR; Denu RA; Zasadil LM; Burkard ME; Weaver BA; Flynn C; Stukenberg PT
    BMC Cancer; 2021 Feb; 21(1):186. PubMed ID: 33622270
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer.
    Chen M; Zhang H; Zhang G; Zhong A; Ma Q; Kai J; Tong Y; Xie S; Wang Y; Zheng H; Guo L; Lu R
    Biochem Biophys Res Commun; 2018 Dec; 507(1-4):74-82. PubMed ID: 30454896
    [TBL] [Abstract][Full Text] [Related]  

  • 3. High chromosome instability identified by low-pass whole-genome sequencing assay is associated with TP53 copy loss and worse prognosis in BRCA1 germline mutation breast cancer.
    Zhu L; Pan JN; Qian Z; Ye WW; Wang XJ; Cao WM
    Breast Cancer; 2022 Jan; 29(1):103-113. PubMed ID: 34403063
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TPX2-p53-GLIPR1 regulatory circuitry in cell proliferation, invasion, and tumor growth of bladder cancer.
    Yan L; Li Q; Yang J; Qiao B
    J Cell Biochem; 2018 Feb; 119(2):1791-1803. PubMed ID: 28799673
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TPX2 as a Novel Prognostic Indicator and Promising Therapeutic Target in Triple-negative Breast Cancer.
    Jiang Y; Liu Y; Tan X; Yu S; Luo J
    Clin Breast Cancer; 2019 Dec; 19(6):450-455. PubMed ID: 31494045
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chromosomal instability selects gene copy-number variants encoding core regulators of proliferation in ER+ breast cancer.
    Endesfelder D; Burrell R; Kanu N; McGranahan N; Howell M; Parker PJ; Downward J; Swanton C; Kschischo M
    Cancer Res; 2014 Sep; 74(17):4853-4863. PubMed ID: 24970479
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression of targeting protein for Xenopus kinesin-like protein 2 is associated with progression of human malignant astrocytoma.
    Li B; Qi XQ; Chen X; Huang X; Liu GY; Chen HR; Huang CG; Luo C; Lu YC
    Brain Res; 2010 Sep; 1352():200-7. PubMed ID: 20599806
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Immunohistochemical detection of Polo-like kinase-1 (PLK1) in primary breast cancer is associated with TP53 mutation and poor clinical outcom.
    King SI; Purdie CA; Bray SE; Quinlan PR; Jordan LB; Thompson AM; Meek DW
    Breast Cancer Res; 2012 Mar; 14(2):R40. PubMed ID: 22405092
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The CIN4 chromosomal instability qPCR classifier defines tumor aneuploidy and stratifies outcome in grade 2 breast cancer.
    Szász AM; Li Q; Eklund AC; Sztupinszki Z; Rowan A; Tőkés AM; Székely B; Kiss A; Szendrői M; Győrffy B; Szállási Z; Swanton C; Kulka J
    PLoS One; 2013; 8(2):e56707. PubMed ID: 23468873
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MYC Dysregulates Mitosis, Revealing Cancer Vulnerabilities.
    Rohrberg J; Van de Mark D; Amouzgar M; Lee JV; Taileb M; Corella A; Kilinc S; Williams J; Jokisch ML; Camarda R; Balakrishnan S; Shankar R; Zhou A; Chang AN; Chen B; Rugo HS; Dumont S; Goga A
    Cell Rep; 2020 Mar; 30(10):3368-3382.e7. PubMed ID: 32160543
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combined Immunohistochemistry of PLK1, p21, and p53 for Predicting TP53 Status: An Independent Prognostic Factor of Breast Cancer.
    Watanabe G; Ishida T; Furuta A; Takahashi S; Watanabe M; Nakata H; Kato S; Ishioka C; Ohuchi N
    Am J Surg Pathol; 2015 Aug; 39(8):1026-34. PubMed ID: 26171916
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TPX2 as a prognostic indicator and potential therapeutic target in clear cell renal cell carcinoma.
    Glaser ZA; Love HD; Guo S; Gellert L; Chang SS; Herrell SD; Barocas DA; Penson DF; Cookson MS; Clark PE
    Urol Oncol; 2017 May; 35(5):286-293. PubMed ID: 28108243
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RAN nucleo-cytoplasmic transport and mitotic spindle assembly partners XPO7 and TPX2 are new prognostic biomarkers in serous epithelial ovarian cancer.
    Cáceres-Gorriti KY; Carmona E; Barrès V; Rahimi K; Létourneau IJ; Tonin PN; Provencher D; Mes-Masson AM
    PLoS One; 2014; 9(3):e91000. PubMed ID: 24625450
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of targeting protein for xklp2 associated with both malignant transformation of respiratory epithelium and progression of squamous cell lung cancer.
    Ma Y; Lin D; Sun W; Xiao T; Yuan J; Han N; Guo S; Feng X; Su K; Mao Y; Cheng S; Gao Y
    Clin Cancer Res; 2006 Feb; 12(4):1121-7. PubMed ID: 16489064
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TPX2 overexpression in medullary thyroid carcinoma mediates TT cell proliferation.
    Yang X; Liu G; Xiao H; Yu F; Xiang X; Lu Y; Li W; Liu X; Li S; Shi Y
    Pathol Oncol Res; 2014 Jul; 20(3):641-8. PubMed ID: 24488334
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comprehensive Analysis of the Oncogenic Role of Targeting Protein for Xklp2 (TPX2) in Human Malignancies.
    Shao T; Jiang X; Bao G; Li C; Guo C
    Dis Markers; 2022; 2022():7571066. PubMed ID: 36304254
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nek9 Phosphorylation Defines a New Role for TPX2 in Eg5-Dependent Centrosome Separation before Nuclear Envelope Breakdown.
    Eibes S; Gallisà-Suñé N; Rosas-Salvans M; Martínez-Delgado P; Vernos I; Roig J
    Curr Biol; 2018 Jan; 28(1):121-129.e4. PubMed ID: 29276125
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation.
    Neumayer G; Helfricht A; Shim SY; Le HT; Lundin C; Belzil C; Chansard M; Yu Y; Lees-Miller SP; Gruss OJ; van Attikum H; Helleday T; Nguyen MD
    J Biol Chem; 2012 Dec; 287(50):42206-22. PubMed ID: 23045526
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tpx2 controls spindle integrity, genome stability, and tumor development.
    Aguirre-Portolés C; Bird AW; Hyman A; Cañamero M; Pérez de Castro I; Malumbres M
    Cancer Res; 2012 Mar; 72(6):1518-28. PubMed ID: 22266221
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Centrosome amplification induces high grade features and is prognostic of worse outcomes in breast cancer.
    Denu RA; Zasadil LM; Kanugh C; Laffin J; Weaver BA; Burkard ME
    BMC Cancer; 2016 Jan; 16():47. PubMed ID: 26832928
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.