BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 33629582)

  • 1. Coexposure to Inhaled Aldehydes or Carbon Dioxide Enhances the Carcinogenic Properties of the Tobacco-Specific Nitrosamine 4-Methylnitrosamino-1-(3-pyridyl)-1-butanone in the A/J Mouse Lung.
    Peterson LA; Oram MK; Flavin M; Seabloom D; Smith WE; O'Sullivan MG; Vevang KR; Upadhyaya P; Stornetta A; Floeder AC; Ho YY; Zhang L; Hecht SS; Balbo S; Wiedmann TS
    Chem Res Toxicol; 2021 Mar; 34(3):723-732. PubMed ID: 33629582
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acrolein Increases the Pulmonary Tumorigenic Activity of the Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Peterson LA; Seabloom D; Smith WE; Vevang KR; Seelig DM; Zhang L; Wiedmann TS
    Chem Res Toxicol; 2022 Oct; 35(10):1831-1839. PubMed ID: 36149460
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The effect of a 2-h exposure to cigarette smoke on the metabolic activation of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mice.
    Brown BG; Richter E; Tricker AR; Ayres PH; Doolittle DJ
    Chem Biol Interact; 2001 Nov; 138(2):125-35. PubMed ID: 11672696
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lung tumor induction in A/J mice by the tobacco smoke carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene: a potentially useful model for evaluation of chemopreventive agents.
    Hecht SS; Isaacs S; Trushin N
    Carcinogenesis; 1994 Dec; 15(12):2721-5. PubMed ID: 8001227
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of lung tumourigenesis by sulindac: comparison of two experimental protocols.
    Castonguay A; Rioux N
    Carcinogenesis; 1997 Mar; 18(3):491-6. PubMed ID: 9067547
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of indole-3-carbinol on lung tumorigenesis and DNA methylation induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and on the metabolism and disposition of NNK in A/J mice.
    Morse MA; LaGreca SD; Amin SG; Chung FL
    Cancer Res; 1990 May; 50(9):2613-7. PubMed ID: 2328487
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The effect of cotinine or cigarette smoke co-administration on the formation of O6-methylguanine adducts in the lung and liver of A/J mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Brown BG; Chang CJ; Ayres PH; Lee CK; Doolittle DJ
    Toxicol Sci; 1999 Jan; 47(1):33-9. PubMed ID: 10048151
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A/J mouse lung tumorigenesis by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its inhibition by arylalkyl isothiocyanates.
    Hecht SS; Morse MA; Eklind KI; Chung FL
    Exp Lung Res; 1991; 17(2):501-11. PubMed ID: 2050046
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tumorigenic activity of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), 4-(methylnitrosamino)-4-(3-pyridyl)-1-butanol (iso-NNAL) and N'-nitrosonornicotine (NNN) on topical application to Sencar mice.
    LaVoie EJ; Prokopczyk G; Rigotty J; Czech A; Rivenson A; Adams JD
    Cancer Lett; 1987 Nov; 37(3):277-83. PubMed ID: 3677059
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice.
    Thomson NM; Kenney PM; Peterson LA
    Chem Res Toxicol; 2003 Jan; 16(1):1-6. PubMed ID: 12693024
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model.
    Megaraj V; Zhou X; Xie F; Liu Z; Yang W; Ding X
    Carcinogenesis; 2014 Jan; 35(1):131-7. PubMed ID: 23917075
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of dietary 1,4-phenylenebis(methylene)selenocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation in lung and liver of A/J mice and F344 rats.
    Prokopczyk B; Cox JE; Upadhyaya P; Amin S; Desai D; Hoffmann D; el-Bayoumy K
    Carcinogenesis; 1996 Apr; 17(4):749-53. PubMed ID: 8625486
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of deuterium substitution on the tumorigenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in A/J mice.
    Hecht SS; Jordan KG; Choi CI; Trushin N
    Carcinogenesis; 1990 Jun; 11(6):1017-20. PubMed ID: 2347060
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An update on the formation in tobacco, toxicity and carcinogenicity of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Peterson LA; Stanfill SB; Hecht SS
    Carcinogenesis; 2024 May; 45(5):275-287. PubMed ID: 38437625
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stereospecific deuterium substitution attenuates the tumorigenicity and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
    Jalas JR; McIntee EJ; Kenney PM; Upadhyaya P; Peterson LA; Hecht SS
    Chem Res Toxicol; 2003 Jun; 16(6):794-806. PubMed ID: 12807363
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of lung lesions in Wistar rats by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its inhibition by aspirin and phenethyl isothiocyanate.
    Ye B; Zhang YX; Yang F; Chen HL; Xia D; Liu MQ; Lai BT
    BMC Cancer; 2007 May; 7():90. PubMed ID: 17535415
    [TBL] [Abstract][Full Text] [Related]  

  • 17. O6-methylguanine is a critical determinant of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenesis in A/J mouse lung.
    Peterson LA; Hecht SS
    Cancer Res; 1991 Oct; 51(20):5557-64. PubMed ID: 1913675
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers and metabolites in the A/J mouse.
    Upadhyaya P; Kenney PM; Hochalter JB; Wang M; Hecht SS
    Carcinogenesis; 1999 Aug; 20(8):1577-82. PubMed ID: 10426810
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation of the transplacental tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.
    Anderson LM; Hecht SS; Dixon DE; Dove LF; Kovatch RM; Amin S; Hoffmann D; Rice JM
    Cancer Res; 1989 Jul; 49(14):3770-5. PubMed ID: 2736518
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of phenethyl isothiocyanate and benzyl isothiocyanate, individually and in combination, on lung tumorigenesis induced in A/J mice by benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
    Hecht SS; Kenney PM; Wang M; Trushin N; Upadhyaya P
    Cancer Lett; 2000 Mar; 150(1):49-56. PubMed ID: 10755386
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.