BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

287 related articles for article (PubMed ID: 33631016)

  • 1. A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study.
    Fangusaro J; Onar-Thomas A; Poussaint TY; Wu S; Ligon AH; Lindeman N; Campagne O; Banerjee A; Gururangan S; Kilburn LB; Goldman S; Qaddoumi I; Baxter P; Vezina G; Bregman C; Patay Z; Jones JY; Stewart CF; Fisher MJ; Doyle LA; Smith M; Dunkel IJ; Fouladi M
    Neuro Oncol; 2021 Oct; 23(10):1777-1788. PubMed ID: 33631016
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial.
    Fangusaro J; Onar-Thomas A; Young Poussaint T; Wu S; Ligon AH; Lindeman N; Banerjee A; Packer RJ; Kilburn LB; Goldman S; Pollack IF; Qaddoumi I; Jakacki RI; Fisher PG; Dhall G; Baxter P; Kreissman SG; Stewart CF; Jones DTW; Pfister SM; Vezina G; Stern JS; Panigrahy A; Patay Z; Tamrazi B; Jones JY; Haque SS; Enterline DS; Cha S; Fisher MJ; Doyle LA; Smith M; Dunkel IJ; Fouladi M
    Lancet Oncol; 2019 Jul; 20(7):1011-1022. PubMed ID: 31151904
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC) study.
    Banerjee A; Jakacki RI; Onar-Thomas A; Wu S; Nicolaides T; Young Poussaint T; Fangusaro J; Phillips J; Perry A; Turner D; Prados M; Packer RJ; Qaddoumi I; Gururangan S; Pollack IF; Goldman S; Doyle LA; Stewart CF; Boyett JM; Kun LE; Fouladi M
    Neuro Oncol; 2017 Aug; 19(8):1135-1144. PubMed ID: 28339824
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ADC Histogram Analysis of Pediatric Low-Grade Glioma Treated with Selumetinib: A Report from the Pediatric Brain Tumor Consortium.
    Vajapeyam S; Brown D; Ziaei A; Wu S; Vezina G; Stern JS; Panigrahy A; Patay Z; Tamrazi B; Jones JY; Haque SS; Enterline DS; Cha S; Jones BV; Yeom KW; Onar-Thomas A; Dunkel IJ; Fouladi M; Fangusaro JR; Poussaint TY
    AJNR Am J Neuroradiol; 2022 Mar; 43(3):455-461. PubMed ID: 35210278
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of surgery in optic pathway/hypothalamic gliomas in children.
    Goodden J; Pizer B; Pettorini B; Williams D; Blair J; Didi M; Thorp N; Mallucci C
    J Neurosurg Pediatr; 2014 Jan; 13(1):1-12. PubMed ID: 24138145
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phase II Study of Selumetinib in Children and Young Adults With Tumors Harboring Activating Mitogen-Activated Protein Kinase Pathway Genetic Alterations: Arm E of the NCI-COG Pediatric MATCH Trial.
    Eckstein OS; Allen CE; Williams PM; Roy-Chowdhuri S; Patton DR; Coffey B; Reid JM; Piao J; Saguilig L; Alonzo TA; Berg SL; Ramirez NC; Jaju A; Mhlanga J; Fox E; Hawkins DS; Mooney MM; Takebe N; Tricoli JV; Janeway KA; Seibel NL; Parsons DW
    J Clin Oncol; 2022 Jul; 40(20):2235-2245. PubMed ID: 35363510
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phase II Weekly Vinblastine for Chemotherapy-Naïve Children With Progressive Low-Grade Glioma: A Canadian Pediatric Brain Tumor Consortium Study.
    Lassaletta A; Scheinemann K; Zelcer SM; Hukin J; Wilson BA; Jabado N; Carret AS; Lafay-Cousin L; Larouche V; Hawkins CE; Pond GR; Poskitt K; Keene D; Johnston DL; Eisenstat DD; Krishnatry R; Mistry M; Arnoldo A; Ramaswamy V; Huang A; Bartels U; Tabori U; Bouffet E
    J Clin Oncol; 2016 Oct; 34(29):3537-3543. PubMed ID: 27573663
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dose-dependent seizure control with MEK inhibitor therapy for progressive glioma in a child with neurofibromatosis type 1.
    Cantor E; Meyer A; Morris SM; Weisenberg JLZ; Brossier NM
    Childs Nerv Syst; 2022 Nov; 38(11):2245-2249. PubMed ID: 35648241
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A phase II study of continuous oral mTOR inhibitor everolimus for recurrent, radiographic-progressive neurofibromatosis type 1-associated pediatric low-grade glioma: a Neurofibromatosis Clinical Trials Consortium study.
    Ullrich NJ; Prabhu SP; Reddy AT; Fisher MJ; Packer R; Goldman S; Robison NJ; Gutmann DH; Viskochil DH; Allen JC; Korf B; Cantor A; Cutter G; Thomas C; Perentesis JP; Mizuno T; Vinks AA; Manley PE; Chi SN; Kieran MW
    Neuro Oncol; 2020 Oct; 22(10):1527-1535. PubMed ID: 32236425
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Trametinib for the treatment of recurrent/progressive pediatric low-grade glioma.
    Manoharan N; Choi J; Chordas C; Zimmerman MA; Scully J; Clymer J; Filbin M; Ullrich NJ; Bandopadhayay P; Chi SN; Yeo KK
    J Neurooncol; 2020 Sep; 149(2):253-262. PubMed ID: 32780261
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A phase II evaluation of selumetinib (AZD6244, ARRY-142886), a selective MEK-1/2 inhibitor in the treatment of recurrent or persistent endometrial cancer: an NRG Oncology/Gynecologic Oncology Group study.
    Coleman RL; Sill MW; Thaker PH; Bender DP; Street D; McGuire WP; Johnston CM; Rotmensch J
    Gynecol Oncol; 2015 Jul; 138(1):30-5. PubMed ID: 25887099
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors.
    Jecrois ES; Zheng W; Bornhorst M; Li Y; Treisman DM; Muguyo D; Huynh S; Andrew SF; Wang Y; Jiang J; Pierce BR; Mao H; Krause MK; Friend A; Nadal-Nicolas F; Stasheff SF; Li W; Zong H; Packer RJ; Zhu Y
    Dev Cell; 2021 Oct; 56(20):2871-2885.e6. PubMed ID: 34428430
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phase II efficacy and pharmacogenomic study of Selumetinib (AZD6244; ARRY-142886) in iodine-131 refractory papillary thyroid carcinoma with or without follicular elements.
    Hayes DN; Lucas AS; Tanvetyanon T; Krzyzanowska MK; Chung CH; Murphy BA; Gilbert J; Mehra R; Moore DT; Sheikh A; Hoskins J; Hayward MC; Zhao N; O'Connor W; Weck KE; Cohen RB; Cohen EE
    Clin Cancer Res; 2012 Apr; 18(7):2056-65. PubMed ID: 22241789
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Population pharmacokinetics and exposure-response of selumetinib and its N-desmethyl metabolite in pediatric patients with neurofibromatosis type 1 and inoperable plexiform neurofibromas.
    Schalkwijk S; Zhou L; Cohen-Rabbie S; Jain L; Freshwater T; So K; He Z; Gioni I; Tomkinson H; Vishwanathan K; Zhou D
    Cancer Chemother Pharmacol; 2021 Aug; 88(2):189-202. PubMed ID: 33903938
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A phase I study of selumetinib (AZD6244/ARRY-142866), a MEK1/2 inhibitor, in combination with cetuximab in refractory solid tumors and KRAS mutant colorectal cancer.
    Deming DA; Cavalcante LL; Lubner SJ; Mulkerin DL; LoConte NK; Eickhoff JC; Kolesar JM; Fioravanti S; Greten TF; Compton K; Doyle AG; Wilding G; Duffy A; Liu G
    Invest New Drugs; 2016 Apr; 34(2):168-75. PubMed ID: 26666244
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Treating non-small cell lung cancer with selumetinib: an up-to-date drug evaluation.
    Imyanitov EN; Levchenko EV; Kuligina ES; Orlov SV
    Expert Opin Pharmacother; 2020 Nov; 21(16):1943-1953. PubMed ID: 32880495
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Low grade chiasmatic-hypothalamic glioma-carboplatin and vincristin chemotherapy effectively defers radiotherapy within a comprehensive treatment strategy -- report from the multicenter treatment study for children and adolescents with a low grade glioma -- HIT-LGG 1996 -- of the Society of Pediatric Oncology and Hematology (GPOH).
    Gnekow AK; Kortmann RD; Pietsch T; Emser A
    Klin Padiatr; 2004; 216(6):331-42. PubMed ID: 15565548
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Optic pathway hypothalamic gliomas in children under three years of age: the role of chemotherapy.
    Silva MM; Goldman S; Keating G; Marymont MA; Kalapurakal J; Tomita T
    Pediatr Neurosurg; 2000 Sep; 33(3):151-8. PubMed ID: 11096362
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluating Focal Areas of Signal Intensity (FASI) in Children with Neurofibromatosis Type-1 (NF1) Treated with Selumetinib on Pediatric Brain Tumor Consortium (PBTC)-029B.
    Pillay-Smiley N; Leach J; Lane A; Hummel T; Fangusaro J; de Blank P
    Cancers (Basel); 2023 Mar; 15(7):. PubMed ID: 37046770
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting the mitogen‑activated protein kinase kinase and protein kinase A pathways overcomes acquired resistance to Selumetinib in low‑grade glioma cells.
    Melotti L; Meco D; Battaglia A; Buzzonetti A; Martini M; Ruggiero A; Scambia G; Riccardi R
    Oncol Rep; 2021 Feb; 45(2):752-763. PubMed ID: 33416182
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.