BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1286 related articles for article (PubMed ID: 33632058)

  • 1. C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
    Beckers J; Tharkeshwar AK; Van Damme P
    Autophagy; 2021 Nov; 17(11):3306-3322. PubMed ID: 33632058
    [TBL] [Abstract][Full Text] [Related]  

  • 2.
    Shao Q; Yang M; Liang C; Ma L; Zhang W; Jiang Z; Luo J; Lee JK; Liang C; Chen JF
    Autophagy; 2020 Sep; 16(9):1635-1650. PubMed ID: 31847700
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The most prevalent genetic cause of ALS-FTD, C9orf72 synergizes the toxicity of ATXN2 intermediate polyglutamine repeats through the autophagy pathway.
    Ciura S; Sellier C; Campanari ML; Charlet-Berguerand N; Kabashi E
    Autophagy; 2016 Aug; 12(8):1406-8. PubMed ID: 27245636
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The progress in
    Jiang L; Zhang T; Lu K; Qi S
    Small GTPases; 2022 Jan; 13(1):56-76. PubMed ID: 33663328
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lysosome dysfunction as a cause of neurodegenerative diseases: Lessons from frontotemporal dementia and amyotrophic lateral sclerosis.
    Root J; Merino P; Nuckols A; Johnson M; Kukar T
    Neurobiol Dis; 2021 Jul; 154():105360. PubMed ID: 33812000
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cellular and physiological functions of C9ORF72 and implications for ALS/FTD.
    Pang W; Hu F
    J Neurochem; 2021 May; 157(3):334-350. PubMed ID: 33259633
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular Mechanisms of Neurodegeneration Related to
    Babić Leko M; Župunski V; Kirincich J; Smilović D; Hortobágyi T; Hof PR; Šimić G
    Behav Neurol; 2019; 2019():2909168. PubMed ID: 30774737
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Autophagy and ALS: mechanistic insights and therapeutic implications.
    Chua JP; De Calbiac H; Kabashi E; Barmada SJ
    Autophagy; 2022 Feb; 18(2):254-282. PubMed ID: 34057020
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis.
    Lan Y; Sullivan PM; Hu F
    Autophagy; 2019 May; 15(5):871-885. PubMed ID: 30696333
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy.
    Yang M; Liang C; Swaminathan K; Herrlinger S; Lai F; Shiekhattar R; Chen JF
    Sci Adv; 2016 Sep; 2(9):e1601167. PubMed ID: 27617292
    [TBL] [Abstract][Full Text] [Related]  

  • 11. UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
    Zhang K; Wang A; Zhong K; Qi S; Wei C; Shu X; Tu WY; Xu W; Xia C; Xiao Y; Chen A; Bai L; Zhang J; Luo B; Wang W; Shen C
    Neuron; 2021 Jun; 109(12):1949-1962.e6. PubMed ID: 33991504
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of C9orf72 hexanucleotide repeat expansion leads to formation of RNA foci and dipeptide repeat proteins but does not influence autophagy or proteasomal function in neuronal cells.
    Leskelä S; Huber N; Hoffmann D; Rostalski H; Remes AM; Takalo M; Hiltunen M; Haapasalo A
    Biochim Biophys Acta Mol Cell Res; 2021 Jun; 1868(7):119021. PubMed ID: 33775797
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inflammasome-Mediated Neuronal-Microglial Crosstalk: a Therapeutic Substrate for the Familial C9orf72 Variant of Frontotemporal Dementia/Amyotrophic Lateral Sclerosis.
    Trageser KJ; Yang EJ; Smith C; Iban-Arias R; Oguchi T; Sebastian-Valverde M; Iqbal UH; Wu H; Estill M; Al Rahim M; Raval U; Herman FJ; Zhang YJ; Petrucelli L; Pasinetti GM
    Mol Neurobiol; 2023 Jul; 60(7):4004-4016. PubMed ID: 37010807
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders.
    Boivin M; Pfister V; Gaucherot A; Ruffenach F; Negroni L; Sellier C; Charlet-Berguerand N
    EMBO J; 2020 Feb; 39(4):e100574. PubMed ID: 31930538
    [TBL] [Abstract][Full Text] [Related]  

  • 15. C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
    Dafinca R; Scaber J; Ababneh N; Lalic T; Weir G; Christian H; Vowles J; Douglas AG; Fletcher-Jones A; Browne C; Nakanishi M; Turner MR; Wade-Martins R; Cowley SA; Talbot K
    Stem Cells; 2016 Aug; 34(8):2063-78. PubMed ID: 27097283
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway.
    Sullivan PM; Zhou X; Robins AM; Paushter DH; Kim D; Smolka MB; Hu F
    Acta Neuropathol Commun; 2016 May; 4(1):51. PubMed ID: 27193190
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DDX3X overexpression decreases dipeptide repeat proteins in a mouse model of C9ORF72-ALS/FTD.
    Fu X; Zhang Z; Hayes LR; Wright N; Asbury J; Li S; Ye Y; Sun S
    Exp Neurol; 2024 Jun; 376():114768. PubMed ID: 38556190
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Proteostasis deregulation as a driver of C9ORF72 pathogenesis.
    Torres P; Cabral-Miranda F; Gonzalez-Teuber V; Hetz C
    J Neurochem; 2021 Dec; 159(6):941-957. PubMed ID: 34679204
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features.
    Shaw MP; Higginbottom A; McGown A; Castelli LM; James E; Hautbergue GM; Shaw PJ; Ramesh TM
    Acta Neuropathol Commun; 2018 Nov; 6(1):125. PubMed ID: 30454072
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pathogenic Mechanisms and Therapy Development for C9orf72 Amyotrophic Lateral Sclerosis/Frontotemporal Dementia.
    Jiang J; Ravits J
    Neurotherapeutics; 2019 Oct; 16(4):1115-1132. PubMed ID: 31667754
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 65.