155 related articles for article (PubMed ID: 33640630)
1. Design, synthesis and biological evaluations of diverse Michael acceptor-based phenazine hybrid molecules as TrxR1 inhibitors.
Zhong Y; Liu J; Cheng X; Zhang H; Zhang C; Xia Z; Wu Z; Zhang L; Zheng Y; Gao Z; Jiang Z; Wang Z; Huang D; Lu Y; Jiang F
Bioorg Chem; 2021 Apr; 109():104736. PubMed ID: 33640630
[TBL] [Abstract][Full Text] [Related]
2. Identification of phenazine analogue as a novel scaffold for thioredoxin reductase I inhibitors against Hep G2 cancer cell lines.
Liao J; Wang L; Wu Z; Wang Z; Chen J; Zhong Y; Jiang F; Lu Y
J Enzyme Inhib Med Chem; 2019 Dec; 34(1):1158-1163. PubMed ID: 31179772
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and biological evaluation of a novel indoleamine 2,3-dioxigenase 1 (IDO1) and thioredoxin reductase (TrxR) dual inhibitor.
Fan QZ; Zhou J; Zhu YB; He LJ; Miao DD; Zhang SP; Liu XP; Zhang C
Bioorg Chem; 2020 Dec; 105():104401. PubMed ID: 33113415
[TBL] [Abstract][Full Text] [Related]
4. Design, facile synthesis and biological evaluations of novel pyrano[3,2-a]phenazine hybrid molecules as antitumor agents.
Lu Y; Yan Y; Wang L; Wang X; Gao J; Xi T; Wang Z; Jiang F
Eur J Med Chem; 2017 Feb; 127():928-943. PubMed ID: 27836197
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and biological evaluation of novel derivatives of dithiodiglycolic acid prepared via oxidative coupling of thiols.
Bakulina O; Bannykh A; Jovanović M; Domračeva I; Podolski-Renić A; Žalubovskis R; Pešić M; Dar'in D; Krasavin M
J Enzyme Inhib Med Chem; 2019 Dec; 34(1):665-671. PubMed ID: 30746961
[TBL] [Abstract][Full Text] [Related]
6. Further exploration of DVD-445 as a lead thioredoxin reductase (TrxR) inhibitor for cancer therapy: Optimization of potency and evaluation of anticancer potential.
Jovanović M; Zhukovsky D; Podolski-Renić A; Žalubovskis R; Dar'in D; Sharoyko V; Tennikova T; Pešić M; Krasavin M
Eur J Med Chem; 2020 Apr; 191():112119. PubMed ID: 32087464
[TBL] [Abstract][Full Text] [Related]
7. Potent inhibition of gastric cancer cells by a natural compound via inhibiting TrxR1 activity and activating ROS-mediated p38 MAPK pathway.
He W; Cao P; Xia Y; Hong L; Zhang T; Shen X; Zheng P; Shen H; Zhao Y; Zou P
Free Radic Res; 2019 Jan; 53(1):104-114. PubMed ID: 30668191
[TBL] [Abstract][Full Text] [Related]
8. Design, combinatorial synthesis and biological evaluations of novel 3-amino-1'-((1-aryl-1H-1,2,3-triazol-5-yl)methyl)-2'-oxospiro[benzo[a] pyrano[2,3-c]phenazine-1,3'-indoline]-2-carbonitrile antitumor hybrid molecules.
Lu Y; Wang L; Wang X; Xi T; Liao J; Wang Z; Jiang F
Eur J Med Chem; 2017 Jul; 135():125-141. PubMed ID: 28441581
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and antiproliferative activity of novel polynuclear heterocyclic compounds derived from 2,3-diaminophenazine.
Mahran AM; Ragab SSh; Hashem AI; Ali MM; Nada AA
Eur J Med Chem; 2015 Jan; 90():568-76. PubMed ID: 25497130
[TBL] [Abstract][Full Text] [Related]
10. Facile Synthesis and Cytotoxicity of Phenazine-Chromene Hybrid Molecules Derived from Phenazine Natural Product.
Zhang MC; Gu SH; Liu GP; Li CC; Xu HM; Wu ZX; Ye BP; Lu YY; Huang DC; Wang ZX; Jiang F
Comb Chem High Throughput Screen; 2019; 22(1):35-40. PubMed ID: 30848195
[TBL] [Abstract][Full Text] [Related]
11. Novel Phenylmethylenecyclohexenone Derivatives as Potent TrxR Inhibitors Display High Antiproliferative Activity and Induce ROS, Apoptosis, and DNA Damage.
Wang X; Qian J; Zhu P; Hua R; Liu J; Hang J; Meng C; Shan W; Miao J; Ling Y
ChemMedChem; 2021 Feb; 16(4):702-712. PubMed ID: 33085980
[TBL] [Abstract][Full Text] [Related]
12. Novel electrophilic amides amenable by the Ugi reaction perturb thioredoxin system via thioredoxin reductase 1 (TrxR1) inhibition: Identification of DVD-445 as a new lead compound for anticancer therapy.
Jovanović M; Zhukovsky D; Podolski-Renić A; Domračeva I; Žalubovskis R; Senćanski M; Glišić S; Sharoyko V; Tennikova T; Dar'in D; Pešić M; Krasavin M
Eur J Med Chem; 2019 Nov; 181():111580. PubMed ID: 31400708
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and cytotoxicity of 6,11-dihydro-pyrido- and 6,11-dihydro-benzo[2,3-b]phenazine-6,11-dione derivatives.
Kim YS; Park SY; Lee HJ; Suh ME; Schollmeyer D; Lee CO
Bioorg Med Chem; 2003 Apr; 11(8):1709-14. PubMed ID: 12659757
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
Zhuo ST; Li CY; Hu MH; Chen SB; Yao PF; Huang SL; Ou TM; Tan JH; An LK; Li D; Gu LQ; Huang ZS
Org Biomol Chem; 2013 Jun; 11(24):3989-4005. PubMed ID: 23657605
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of novel benzo[a]pyridazino[3,4-c]phenazine derivatives.
Le-Nhat-Thuy G; Dang Thi TA; Nguyen Thi QG; Hoang Thi P; Nguyen TA; Nguyen HT; Nguyen Thi TH; Nguyen HS; Nguyen TV
Bioorg Med Chem Lett; 2021 Jul; 43():128054. PubMed ID: 33895275
[TBL] [Abstract][Full Text] [Related]
16. Novel angular benzophenazines: dual topoisomerase I and topoisomerase II inhibitors as potential anticancer agents.
Vicker N; Burgess L; Chuckowree IS; Dodd R; Folkes AJ; Hardick DJ; Hancox TC; Miller W; Milton J; Sohal S; Wang S; Wren SP; Charlton PA; Dangerfield W; Liddle C; Mistry P; Stewart AJ; Denny WA
J Med Chem; 2002 Jan; 45(3):721-39. PubMed ID: 11806724
[TBL] [Abstract][Full Text] [Related]
17. Bis(phenazine-1-carboxamides): structure-activity relationships for a new class of dual topoisomerase I/II-directed anticancer drugs.
Spicer JA; Gamage SA; Rewcastle GW; Finlay GJ; Bridewell DJ; Baguley BC; Denny WA
J Med Chem; 2000 Apr; 43(7):1350-8. PubMed ID: 10753472
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and biological evaluation of heterocyclic azoles derivatives containing pyrazine moiety as potential telomerase inhibitors.
Zhang YB; Wang XL; Liu W; Yang YS; Tang JF; Zhu HL
Bioorg Med Chem; 2012 Nov; 20(21):6356-65. PubMed ID: 23018096
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and biological evaluation of 1H-indazole derivatives as novel ASK1 inhibitors.
Hou S; Yang X; Yang Y; Tong Y; Chen Q; Wan B; Wei R; Lu T; Chen Y; Hu Q
Eur J Med Chem; 2021 Aug; 220():113482. PubMed ID: 33906048
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs.
Lu GQ; Li XY; Mohamed O K; Wang D; Meng FH
Eur J Med Chem; 2019 Jun; 171():282-296. PubMed ID: 30927565
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]