BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 33640631)

  • 1. Design and synthesis of novel 3,4-dihydrocoumarins as potent and selective monoamine oxidase-B inhibitors with the neuroprotection against Parkinson's disease.
    Liu L; Chen Y; Zeng RF; Liu Y; Xie SS; Lan JS; Ding Y; Yang YT; Yang J; Zhang T
    Bioorg Chem; 2021 Apr; 109():104685. PubMed ID: 33640631
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of 3,4-dichloro-N-(1H-indol-5-yl)benzamide: A highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability profile and neuroprotective action.
    Elkamhawy A; Kim HJ; Elsherbeny MH; Paik S; Park JH; Gotina L; Abdellattif MH; Gouda NA; Cho J; Lee K; Nim Pae A; Park KD; Roh EJ
    Bioorg Chem; 2021 Nov; 116():105352. PubMed ID: 34562673
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of novel and potent safinamide-based derivatives as highly selective hMAO-B inhibitors for treatment of Parkinson's disease (PD): Design, synthesis, in vitro, in vivo and in silico biological studies.
    Elkamhawy A; Paik S; Park JH; Kim HJ; Hassan AHE; Lee K; Park KD; Roh EJ
    Bioorg Chem; 2021 Oct; 115():105233. PubMed ID: 34390968
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and biological evaluation of rasagiline-clorgyline hybrids as novel dual inhibitors of monoamine oxidase-B and amyloid-β aggregation against Alzheimer's disease.
    Xie SS; Liu J; Tang C; Pang C; Li Q; Qin Y; Nong X; Zhang Z; Guo J; Cheng M; Tang W; Liang N; Jiang N
    Eur J Med Chem; 2020 Sep; 202():112475. PubMed ID: 32652406
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Benzopyrone Biochanin-A as a reversible, competitive, and selective monoamine oxidase B inhibitor.
    Zarmouh NO; Eyunni SK; Soliman KF
    BMC Complement Altern Med; 2017 Jan; 17(1):34. PubMed ID: 28069007
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of novel benzimidazole derivatives as selective and reversible monoamine oxidase B inhibitors for Parkinson's disease treatment.
    Lv Y; Fan M; He J; Song X; Guo J; Gao B; Zhang J; Zhang C; Xie Y
    Eur J Med Chem; 2024 Aug; 274():116566. PubMed ID: 38838545
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Halogenated class of oximes as a new class of monoamine oxidase-B inhibitors for the treatment of Parkinson's disease: Synthesis, biochemistry, and molecular dynamics study.
    Thomas Parambi DG; Oh JM; Kumar S; Sudevan ST; Hendawy OM; Abdelgawad MA; Musa A; Al-Sanea MM; Ahmad I; Patel H; Kim H; Mathew B
    Comput Biol Chem; 2023 Aug; 105():107899. PubMed ID: 37315342
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and bioevalucation of novel 2,3-dihydro-1H-inden-1-amine derivatives as potent and selective human monoamine oxidase B inhibitors based on rasagiline.
    Xiao X; Zhang XX; Zhan MM; Cheng K; Li S; Xie Z; Liao C
    Eur J Med Chem; 2018 Feb; 145():588-593. PubMed ID: 29339253
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Osthenol, a prenylated coumarin, as a monoamine oxidase A inhibitor with high selectivity.
    Baek SC; Kang MG; Park JE; Lee JP; Lee H; Ryu HW; Park CM; Park D; Cho ML; Oh SR; Kim H
    Bioorg Med Chem Lett; 2019 Mar; 29(6):839-843. PubMed ID: 30686752
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel 1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-indene-4-thiol derivatives as potent selective human monoamine oxidase B inhibitors: Design, SAR development, and biological evaluation.
    Kong H; Meng X; Hou R; Yang X; Han J; Xie Z; Duan Y; Liao C
    Bioorg Med Chem Lett; 2021 Jul; 43():128051. PubMed ID: 33887441
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel C7-Substituted Coumarins as Selective Monoamine Oxidase Inhibitors: Discovery, Synthesis and Theoretical Simulation.
    Wang D; Hong RY; Guo M; Liu Y; Chen N; Li X; Kong DX
    Molecules; 2019 Nov; 24(21):. PubMed ID: 31694262
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal structures, binding interactions, and ADME evaluation of brain penetrant N-substituted indazole-5-carboxamides as subnanomolar, selective monoamine oxidase B and dual MAO-A/B inhibitors.
    Tzvetkov NT; Stammler HG; Neumann B; Hristova S; Antonov L; Gastreich M
    Eur J Med Chem; 2017 Feb; 127():470-492. PubMed ID: 28107736
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel tricyclic pyrazolo[1,5-d][1,4]benzoxazepin-5(6H)-one: Design, synthesis, model and use as hMAO-B inhibitors.
    Chen R; Xiao J; Ni Y; Xu HF; Zheng M; Tong X; Zhang TT; Liao C; Tang WJ
    Bioorg Med Chem; 2016 Apr; 24(8):1741-8. PubMed ID: 26964672
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Monoamine oxidase A and B inhibitory activities of 3,5-diphenyl-1,2,4-triazole substituted [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives.
    Bekircan O; Danış Ö; Şahin ME; Çetin M
    Bioorg Chem; 2022 Jan; 118():105493. PubMed ID: 34814086
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and biological evaluation of novel coumarin-N-benzyl pyridinium hybrids as multi-target agents for the treatment of Alzheimer's disease.
    Lan JS; Ding Y; Liu Y; Kang P; Hou JW; Zhang XY; Xie SS; Zhang T
    Eur J Med Chem; 2017 Oct; 139():48-59. PubMed ID: 28797883
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, human monoamine oxidase inhibitory activity and molecular docking studies of 3-heteroarylcoumarin derivatives.
    Delogu G; Picciau C; Ferino G; Quezada E; Podda G; Uriarte E; Viña D
    Eur J Med Chem; 2011 Apr; 46(4):1147-52. PubMed ID: 21316817
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel 2H-chromen-2-one derivatives of resveratrol: Design, synthesis, modeling and use as human monoamine oxidase inhibitors.
    Ruan BF; Cheng HJ; Ren J; Li HL; Guo LL; Zhang XX; Liao C
    Eur J Med Chem; 2015 Oct; 103():185-90. PubMed ID: 26352677
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New coumarin derivatives: design, synthesis and use as inhibitors of hMAO.
    He X; Chen YY; Shi JB; Tang WJ; Pan ZX; Dong ZQ; Song BA; Li J; Liu XH
    Bioorg Med Chem; 2014 Jul; 22(14):3732-8. PubMed ID: 24856304
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases.
    Farina R; Pisani L; Catto M; Nicolotti O; Gadaleta D; Denora N; Soto-Otero R; Mendez-Alvarez E; Passos CS; Muncipinto G; Altomare CD; Nurisso A; Carrupt PA; Carotti A
    J Med Chem; 2015 Jul; 58(14):5561-78. PubMed ID: 26107513
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ethyl Acetohydroxamate Incorporated Chalcones: Unveiling a Novel Class of Chalcones for Multitarget Monoamine Oxidase-B Inhibitors Against Alzheimer's Disease.
    Reeta ; Baek SC; Lee JP; Rangarajan TM; Ayushee ; Singh RP; Singh M; Mangiatordi GF; Nicolotti O; Kim H; Mathew B
    CNS Neurol Disord Drug Targets; 2019; 18(8):643-654. PubMed ID: 31550216
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.