BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 33647739)

  • 1. Dual-target platinum(IV) complexes exhibit antiproliferative activity through DNA damage and induce ER-stress-mediated apoptosis in A549 cells.
    Wang M; Liu Z; Huang X; Chen Y; Wang Y; Kong J; Yang Y; Yu C; Li J; Wang X; Wang H
    Bioorg Chem; 2021 May; 110():104741. PubMed ID: 33647739
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitochondria-targeted platinum(II) complexes induce apoptosis-dependent autophagic cell death mediated by ER-stress in A549 cancer cells.
    Wang FY; Tang XM; Wang X; Huang KB; Feng HW; Chen ZF; Liu YN; Liang H
    Eur J Med Chem; 2018 Jul; 155():639-650. PubMed ID: 29935437
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dual-targeting antitumor conjugates derived from platinum(IV) prodrugs and microtubule inhibitor CA-4 significantly exhibited potent ability to overcome cisplatin resistance.
    Huang X; Wang M; Wang C; Hu W; You Q; Yang Y; Yu C; Liao Z; Gou S; Wang H
    Bioorg Chem; 2019 Nov; 92():103236. PubMed ID: 31494328
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting RAS-RAF pathway significantly improves antitumor activity of Rigosertib-derived platinum(IV) complexes and overcomes cisplatin resistance.
    Liu Z; Wang M; Wang H; Fang L; Gou S
    Eur J Med Chem; 2020 May; 194():112269. PubMed ID: 32248002
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chlorambucil-conjugated platinum(IV) prodrugs to treat triple-negative breast cancer in vitro and in vivo.
    Ma ZY; Wang DB; Song XQ; Wu YG; Chen Q; Zhao CL; Li JY; Cheng SH; Xu JY
    Eur J Med Chem; 2018 Sep; 157():1292-1299. PubMed ID: 30195239
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel NF-κB Inhibitor-Conjugated Pt(IV) Prodrug to Enable Cancer Therapy through ROS/ER Stress and Mitochondrial Dysfunction and Overcome Multidrug Resistance.
    Wang M; Li G; Jiang G; Cai J; Liu Z; Huang R; Huang X; Wang H
    J Med Chem; 2024 Apr; 67(8):6218-6237. PubMed ID: 38573870
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Complexes of oxoplatin with rhein and ferulic acid ligands as platinum(iv) prodrugs with high anti-tumor activity.
    Tan MX; Wang ZF; Qin QP; Zou BQ; Liang H
    Dalton Trans; 2020 Feb; 49(5):1613-1619. PubMed ID: 31942585
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and biological evaluation of dihydro-2-quinolone platinum(iv) hybrids as antitumor agents displaying mitochondria injury and DNA damage mechanism.
    Liu Z; Li Z; Du T; Chen Y; Wang Q; Li G; Liu M; Zhang N; Li D; Han J
    Dalton Trans; 2021 Jan; 50(1):362-375. PubMed ID: 33319888
    [TBL] [Abstract][Full Text] [Related]  

  • 9. E platinum, a newly synthesized platinum compound, induces apoptosis through ROS-triggered ER stress in gastric carcinoma cells.
    Wang X; Guo Q; Tao L; Zhao L; Chen Y; An T; Chen Z; Fu R
    Mol Carcinog; 2017 Jan; 56(1):218-231. PubMed ID: 27061377
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis and biological evaluation of a novel series of glycosylated platinum(iv) complexes as antitumor agents.
    Wang Q; Huang Z; Ma J; Lu X; Zhang L; Wang X; George Wang P
    Dalton Trans; 2016 Jun; 45(25):10366-74. PubMed ID: 27252024
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Conjugation of platinum(IV) complexes with chlorambucil to overcome cisplatin resistance via a "joint action" mode toward DNA.
    Qin X; Fang L; Chen F; Gou S
    Eur J Med Chem; 2017 Sep; 137():167-175. PubMed ID: 28586717
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Effects of Newly Synthesized Platinum(IV) Complexes on Cytotoxicity and Radiosensitization of Human Tumour Cells
    Petrovic M; Popovic S; Baskic D; Todorovic M; Djurdjevic P; Ristic-Fira A; Keta O; Petkovic V; Koricanac L; Stojkovic D; Jevtic V; Trifunovic S; Todorovic D
    Anticancer Res; 2020 Sep; 40(9):5001-5013. PubMed ID: 32878788
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 5-Bromo-oxoisoaporphine platinum(II) complexes exhibit tumor cell cytotoxcicity via inhibition of telomerase activity and disruption of c-myc G-quadruplex DNA and mitochondrial functions.
    Wei ZZ; Qin QP; Meng T; Deng CX; Liang H; Chen ZF
    Eur J Med Chem; 2018 Feb; 145():360-369. PubMed ID: 29335202
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis and biological evaluation of naphthalenebenzimidizole platinum (II) complexes as potential antitumor agents.
    Liang GB; Yu YC; Wei JH; Kuang WB; Chen ZF; Zhang Y
    Eur J Med Chem; 2020 Feb; 188():112033. PubMed ID: 31923857
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Maximizing Synergistic Activity When Combining RNAi and Platinum-Based Anticancer Agents.
    Xiao H; Qi R; Li T; Awuah SG; Zheng Y; Wei W; Kang X; Song H; Wang Y; Yu Y; Bird MA; Jing X; Yaffe MB; Birrer MJ; Ghoroghchian PP
    J Am Chem Soc; 2017 Mar; 139(8):3033-3044. PubMed ID: 28166401
    [TBL] [Abstract][Full Text] [Related]  

  • 16. On the stability and biological behavior of cyclometallated Pt(IV) complexes with halido and aryl ligands in the axial positions.
    Escolà A; Crespo M; López C; Quirante J; Jayaraman A; Polat IH; Badía J; Baldomà L; Cascante M
    Bioorg Med Chem; 2016 Nov; 24(22):5804-5815. PubMed ID: 27670096
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Naproxen platinum(iv) hybrids inhibiting cycloxygenases and matrix metalloproteinases and causing DNA damage: synthesis and biological evaluation as antitumor agents in vitro and in vivo.
    Chen Y; Wang Q; Li Z; Liu Z; Zhao Y; Zhang J; Liu M; Wang Z; Li D; Han J
    Dalton Trans; 2020 Apr; 49(16):5192-5204. PubMed ID: 32236281
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhancing Cytotoxicity of a Monofunctional Platinum Complex via a Dual-DNA-Damage Approach.
    Guo Y; He Y; Wu S; Zhang S; Song D; Zhu Z; Guo Z; Wang X
    Inorg Chem; 2019 Oct; 58(19):13150-13160. PubMed ID: 31539237
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of a new series of low toxic naphthalimide platinum(IV) antitumor complexes with dual DNA damage mechanism.
    Wang Q; Tan X; Liu Z; Li G; Zhang R; Wei J; Wang S; Li D; Wang B; Han J
    Eur J Pharm Sci; 2018 Nov; 124():127-136. PubMed ID: 30153524
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel star-shaped trinuclear platinum(II) complex based on a 1,3,5-triazine core displaying potent antiproliferative activity against TNBC by the mitochondrial injury and DNA damage mechanism.
    Wu Y; Zhao D; Shang J; Huang W; Chen Z
    Dalton Trans; 2022 Jul; 51(29):10930-10942. PubMed ID: 35731536
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.