BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

314 related articles for article (PubMed ID: 33649594)

  • 1. Transcription factor competition at the γ-globin promoters controls hemoglobin switching.
    Liu N; Xu S; Yao Q; Zhu Q; Kai Y; Hsu JY; Sakon P; Pinello L; Yuan GC; Bauer DE; Orkin SH
    Nat Genet; 2021 Apr; 53(4):511-520. PubMed ID: 33649594
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
    Liu N; Hargreaves VV; Zhu Q; Kurland JV; Hong J; Kim W; Sher F; Macias-Trevino C; Rogers JM; Kurita R; Nakamura Y; Yuan GC; Bauer DE; Xu J; Bulyk ML; Orkin SH
    Cell; 2018 Apr; 173(2):430-442.e17. PubMed ID: 29606353
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of γ-globin gene expression by GATA1 and NF-Y in hereditary persistence of fetal hemoglobin.
    Doerfler PA; Feng R; Li Y; Palmer LE; Porter SN; Bell HW; Crossley M; Pruett-Miller SM; Cheng Y; Weiss MJ
    Nat Genet; 2021 Aug; 53(8):1177-1186. PubMed ID: 34341563
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage-specific expression of human γ-globin gene.
    Zhu X; Wang Y; Pi W; Liu H; Wickrema A; Tuan D
    PLoS One; 2012; 7(10):e47175. PubMed ID: 23071749
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human globin knock-in mice complete fetal-to-adult hemoglobin switching in postnatal development.
    McConnell SC; Huo Y; Liu S; Ryan TM
    Mol Cell Biol; 2011 Feb; 31(4):876-83. PubMed ID: 21173165
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.
    Rajendiran V; Devaraju N; Haddad M; Ravi NS; Panigrahi L; Paul J; Gopalakrishnan C; Wyman S; Ariudainambi K; Mahalingam G; Periyasami Y; Prasad K; George A; Sukumaran D; Gopinathan S; Pai AA; Nakamura Y; Balasubramanian P; Ramalingam R; Thangavel S; Velayudhan SR; Corn JE; Mackay JP; Marepally S; Srivastava A; Crossley M; Mohankumar KM
    Mol Ther; 2024 Mar; 32(3):663-677. PubMed ID: 38273654
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition.
    Traxler EA; Yao Y; Wang YD; Woodard KJ; Kurita R; Nakamura Y; Hughes JR; Hardison RC; Blobel GA; Li C; Weiss MJ
    Nat Med; 2016 Sep; 22(9):987-90. PubMed ID: 27525524
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B.
    Papadopoulos P; Kafasi A; De Cuyper IM; Barroca V; Lewandowski D; Kadri Z; Veldthuis M; Berghuis J; Gillemans N; Benavente Cuesta CM; Grosveld FG; van Zwieten R; Philipsen S; Vernet M; Gutiérrez L; Patrinos GP
    Hum Genomics; 2020 Oct; 14(1):39. PubMed ID: 33066815
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATF4 Regulates MYB to Increase γ-Globin in Response to Loss of β-Globin.
    Boontanrart MY; Schröder MS; Stehli GM; Banović M; Wyman SK; Lew RJ; Bordi M; Gowen BG; DeWitt MA; Corn JE
    Cell Rep; 2020 Aug; 32(5):107993. PubMed ID: 32755585
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CRISPR/Cas9-based multiplex genome editing of BCL11A and HBG efficiently induces fetal hemoglobin expression.
    Han Y; Tan X; Jin T; Zhao S; Hu L; Zhang W; Kurita R; Nakamura Y; Liu J; Li D; Zhang Z; Fang X; Huang S
    Eur J Pharmacol; 2022 Mar; 918():174788. PubMed ID: 35093321
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.
    Roosjen M; McColl B; Kao B; Gearing LJ; Blewitt ME; Vadolas J
    FASEB J; 2014 Apr; 28(4):1610-20. PubMed ID: 24371119
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LRF Promotes Indirectly Advantageous Chromatin Conformation via
    Chondrou V; Shaukat AN; Psarias G; Athanasopoulou K; Iliopoulou E; Damanaki A; Stathopoulos C; Sgourou A
    Int J Mol Sci; 2022 Jun; 23(13):. PubMed ID: 35806029
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA methylation patterns of β-globin cluster in β-thalassemia patients.
    Bao X; Zuo Y; Chen D; Zhao C
    Clin Epigenetics; 2020 Dec; 12(1):187. PubMed ID: 33272312
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Editing a γ-globin repressor binding site restores fetal hemoglobin synthesis and corrects the sickle cell disease phenotype.
    Weber L; Frati G; Felix T; Hardouin G; Casini A; Wollenschlaeger C; Meneghini V; Masson C; De Cian A; Chalumeau A; Mavilio F; Amendola M; Andre-Schmutz I; Cereseto A; El Nemer W; Concordet JP; Giovannangeli C; Cavazzana M; Miccio A
    Sci Adv; 2020 Feb; 6(7):. PubMed ID: 32917636
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
    Sankaran VG; Menne TF; Xu J; Akie TE; Lettre G; Van Handel B; Mikkola HK; Hirschhorn JN; Cantor AB; Orkin SH
    Science; 2008 Dec; 322(5909):1839-42. PubMed ID: 19056937
    [TBL] [Abstract][Full Text] [Related]  

  • 16. let-7 miRNAs repress HIC2 to regulate BCL11A transcription and hemoglobin switching.
    Huang P; Peslak SA; Shehu V; Keller CA; Giardine B; Shi J; Hardison RC; Blobel GA; Khandros E
    Blood; 2024 May; 143(19):1980-1991. PubMed ID: 38364109
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evidence for a bigenic chromatin subdomain in regulation of the fetal-to-adult hemoglobin switch.
    Beauchemin H; Trudel M
    Mol Cell Biol; 2009 Mar; 29(6):1635-48. PubMed ID: 19114559
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.
    Ravi NS; Wienert B; Wyman SK; Bell HW; George A; Mahalingam G; Vu JT; Prasad K; Bandlamudi BP; Devaraju N; Rajendiran V; Syedbasha N; Pai AA; Nakamura Y; Kurita R; Narayanasamy M; Balasubramanian P; Thangavel S; Marepally S; Velayudhan SR; Srivastava A; DeWitt MA; Crossley M; Corn JE; Mohankumar KM
    Elife; 2022 Feb; 11():. PubMed ID: 35147495
    [TBL] [Abstract][Full Text] [Related]  

  • 19. miR-30a regulates γ-globin expression in erythoid precursors of intermedia thalassemia through targeting BCL11A.
    Gholampour MA; Asadi M; Naderi M; Azarkeivan A; Soleimani M; Atashi A
    Mol Biol Rep; 2020 May; 47(5):3909-3918. PubMed ID: 32406020
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs.
    Fornari TA; Lanaro C; Albuquerque DM; Ferreira R; Costa FF
    Exp Biol Med (Maywood); 2017 Feb; 242(3):267-274. PubMed ID: 27591578
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.