These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 33655394)

  • 1. High-Throughput, Fluorescence-Based Esterase Activity Assay for Assessing Polysorbate Degradation Risk during Biopharmaceutical Development.
    Bhargava AC; Mains K; Siu A; Gu J; Zarzar J; Yi L; Yuk IH
    Pharm Res; 2021 Mar; 38(3):397-413. PubMed ID: 33655394
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of Recombinantly-Expressed Hydrolytic Enzymes from Chinese Hamster Ovary Cells: Identification of Host Cell Proteins that Degrade Polysorbate.
    Kovner D; Yuk IH; Shen A; Li H; Graf T; Gupta S; Liu W; Tomlinson A
    J Pharm Sci; 2023 May; 112(5):1351-1363. PubMed ID: 36646283
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Assessing the polysorbate degradation fingerprints and kinetics of lipases - how the activity of polysorbate degrading hydrolases is influenced by the assay and assay conditions.
    Glücklich N; Carle S; Buske J; Mäder K; Garidel P
    Eur J Pharm Sci; 2021 Nov; 166():105980. PubMed ID: 34419573
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Acidic and alkaline hydrolysis of polysorbates under aqueous conditions: Towards understanding polysorbate degradation in biopharmaceutical formulations.
    Dwivedi M; Buske J; Haemmerling F; Blech M; Garidel P
    Eur J Pharm Sci; 2020 Mar; 144():105211. PubMed ID: 31931121
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A fast and sensitive high-throughput assay to assess polysorbate-degrading hydrolytic activity in biopharmaceuticals.
    Gupta SK; Graf T; Edelmann FT; Seelmann H; Reintinger M; Hillringhaus L; Bergmann F; Wiedmann M; Falkenstein R; Wegele H; Yuk IH; Leiss M
    Eur J Pharm Biopharm; 2023 Jun; 187():120-129. PubMed ID: 37116764
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stress-mediated polysorbate 20 degradation and its potential impact on therapeutic proteins.
    Aryal B; Lehtimaki M; Rao VA
    Pharm Res; 2024 Jun; 41(6):1217-1232. PubMed ID: 38740663
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Rapid High-Sensitivity Reversed-Phase Ultra High Performance Liquid Chromatography Mass Spectrometry Method for Assessing Polysorbate 20 Degradation in Protein Therapeutics.
    Cheng Y; Hu M; Zamiri C; Carcelen T; Demeule B; Tomlinson A; Gu J; Yigzaw Y; Kalo M; Yu XC
    J Pharm Sci; 2019 Sep; 108(9):2880-2886. PubMed ID: 31054888
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Measuring Lipolytic Activity to Support Process Improvements to Manage Lipase-Mediated Polysorbate Degradation.
    Jahn M; Zerr A; Fedorowicz FM; Brigger F; Koulov A; Mahler HC
    Pharm Res; 2020 Jun; 37(6):118. PubMed ID: 32495187
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A comparison of Polysorbates and Alternative Surfactants for Interfacial Stress Protection and Mitigation of Fatty Acid Particle Formation in the Presence of an Esterase.
    Roy I; Wuchner K; Stahl P; Tran T; Yaragudi N
    J Pharm Sci; 2024 Sep; 113(9):2688-2698. PubMed ID: 39009347
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Controlled polysorbate 20 hydrolysis - A new approach to assess the impact of polysorbate 20 degradation on biopharmaceutical product quality in shortened time.
    Graf T; Abstiens K; Wedekind F; Elger C; Haindl M; Wurth C; Leiss M
    Eur J Pharm Biopharm; 2020 Jul; 152():318-326. PubMed ID: 32445968
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Analysis methods of polysorbate 20: A new method to assess the stability of polysorbate 20 and established methods that may overlook degraded polysorbate 20.
    Khossravi M; Kao YH; Mrsny RJ; Sweeney TD
    Pharm Res; 2002 May; 19(5):634-9. PubMed ID: 12069166
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High-Throughput Fluorometric Assay For Quantifying Polysorbate In Biopharmaceutical Products Using Micelle Activated Fluorescence Probe N-Phenyl-1-Naphthylamine.
    Dow XY; Gao Q; Sperduto JL; Wen X; Thai C; Zhang L; McCoy MA
    Pharm Res; 2024 Jul; 41(7):1455-1473. PubMed ID: 38955997
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Microtiter Plate-Based Assay to Screen for Active and Stereoselective Hydrolytic Enzymes in Enzyme Libraries.
    Böttcher D; Zägel P; Schmidt M; Bornscheuer UT
    Methods Mol Biol; 2017; 1539():197-204. PubMed ID: 27900690
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Investigation of excipients impact on polysorbate 80 degradation in biopharmaceutical formulation buffers.
    Bai L; Zhang Y; Zhang C; Lu Y; Li Z; Huang G; Meng B
    J Pharm Biomed Anal; 2023 Sep; 233():115496. PubMed ID: 37285658
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Profiling Active Enzymes for Polysorbate Degradation in Biotherapeutics by Activity-Based Protein Profiling.
    Li X; Chandra D; Letarte S; Adam GC; Welch J; Yang RS; Rivera S; Bodea S; Dow A; Chi A; Strulson CA; Richardson DD
    Anal Chem; 2021 Jun; 93(23):8161-8169. PubMed ID: 34032423
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparison of Polysorbate 80 Hydrolysis and Oxidation on the Aggregation of a Monoclonal Antibody.
    Larson NR; Wei Y; Prajapati I; Chakraborty A; Peters B; Kalonia C; Hudak S; Choudhary S; Esfandiary R; Dhar P; Schöneich C; Middaugh CR
    J Pharm Sci; 2020 Jan; 109(1):633-639. PubMed ID: 31758949
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of Fatty Acid Composition in Polysorbate 80 on the Stability of Therapeutic Protein Formulations.
    Pegues MA; Szczepanek K; Sheikh F; Thacker SG; Aryal B; Ghorab MK; Wolfgang S; Donnelly RP; Verthelyi D; Rao VA
    Pharm Res; 2021 Nov; 38(11):1961-1975. PubMed ID: 34845573
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mixed carbonates as useful substrates for a fluorogenic assay for lipases and esterases.
    Zadlo A; Koszelewski D; Borys F; Ostaszewski R
    Chembiochem; 2015 Mar; 16(4):677-82. PubMed ID: 25648400
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional-Based Screening Methods for Detecting Esterase and Lipase Activity Against Multiple Substrates.
    Reyes-Duarte D; Coscolín C; Martínez-Martínez M; Ferrer M; García-Arellano H
    Methods Mol Biol; 2018; 1835():109-117. PubMed ID: 30109647
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of alpha-cyanoesters as fluorescent substrates for examining interindividual variation in general and pyrethroid-selective esterases in human liver microsomes.
    Wheelock CE; Wheelock AM; Zhang R; Stok JE; Morisseau C; Le Valley SE; Green CE; Hammock BD
    Anal Biochem; 2003 Apr; 315(2):208-22. PubMed ID: 12689831
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.