BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 33657327)

  • 1. Transcriptome Sequencing of Patients With Hypertrophic Cardiomyopathy Reveals Novel Splice-Altering Variants in
    Holliday M; Singer ES; Ross SB; Lim S; Lal S; Ingles J; Semsarian C; Bagnall RD
    Circ Genom Precis Med; 2021 Apr; 14(2):e003202. PubMed ID: 33657327
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Key Value of RNA Analysis of MYBPC3 Splice-Site Variants in Hypertrophic Cardiomyopathy.
    Singer ES; Ingles J; Semsarian C; Bagnall RD
    Circ Genom Precis Med; 2019 Jan; 12(1):e002368. PubMed ID: 30645170
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Myosin inhibitor reverses hypertrophic cardiomyopathy in genotypically diverse pediatric iPSC-cardiomyocytes to mirror variant correction.
    Kinnear C; Said A; Meng G; Zhao Y; Wang EY; Rafatian N; Parmar N; Wei W; Billia F; Simmons CA; Radisic M; Ellis J; Mital S
    Cell Rep Med; 2024 May; 5(5):101520. PubMed ID: 38642550
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation of MYBPC3 trans-Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes.
    Prondzynski M; Krämer E; Laufer SD; Shibamiya A; Pless O; Flenner F; Müller OJ; Münch J; Redwood C; Hansen A; Patten M; Eschenhagen T; Mearini G; Carrier L
    Mol Ther Nucleic Acids; 2017 Jun; 7():475-486. PubMed ID: 28624223
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Serum supplemented culture medium masks hypertrophic phenotypes in human pluripotent stem cell derived cardiomyocytes.
    Dambrot C; Braam SR; Tertoolen LG; Birket M; Atsma DE; Mummery CL
    J Cell Mol Med; 2014 Aug; 18(8):1509-18. PubMed ID: 24981391
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Slower Calcium Handling Balances Faster Cross-Bridge Cycling in Human
    Pioner JM; Vitale G; Steczina S; Langione M; Margara F; Santini L; Giardini F; Lazzeri E; Piroddi N; Scellini B; Palandri C; Schuldt M; Spinelli V; Girolami F; Mazzarotto F; van der Velden J; Cerbai E; Tesi C; Olivotto I; Bueno-Orovio A; Sacconi L; Coppini R; Ferrantini C; Regnier M; Poggesi C
    Circ Res; 2023 Mar; 132(5):628-644. PubMed ID: 36744470
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay.
    Seeger T; Shrestha R; Lam CK; Chen C; McKeithan WL; Lau E; Wnorowski A; McMullen G; Greenhaw M; Lee J; Oikonomopoulos A; Lee S; Yang H; Mercola M; Wheeler M; Ashley EA; Yang F; Karakikes I; Wu JC
    Circulation; 2019 Feb; 139(6):799-811. PubMed ID: 30586709
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic cardiomyopathy.
    Steczina S; Mohran S; Bailey LRJ; McMillen TS; Kooiker KB; Wood NB; Davis J; Previs MJ; Olivotto I; Pioner JM; Geeves MA; Poggesi C; Regnier M
    J Mol Cell Cardiol; 2024 Jun; 191():27-39. PubMed ID: 38648963
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity.
    Liang P; Lan F; Lee AS; Gong T; Sanchez-Freire V; Wang Y; Diecke S; Sallam K; Knowles JW; Wang PJ; Nguyen PK; Bers DM; Robbins RC; Wu JC
    Circulation; 2013 Apr; 127(16):1677-91. PubMed ID: 23519760
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Isogenic Pairs of hiPSC-CMs with Hypertrophic Cardiomyopathy/LVNC-Associated ACTC1 E99K Mutation Unveil Differential Functional Deficits.
    Smith JGW; Owen T; Bhagwan JR; Mosqueira D; Scott E; Mannhardt I; Patel A; Barriales-Villa R; Monserrat L; Hansen A; Eschenhagen T; Harding SE; Marston S; Denning C
    Stem Cell Reports; 2018 Nov; 11(5):1226-1243. PubMed ID: 30392975
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Complex aberrant splicing in the induced pluripotent stem cell-derived cardiomyocytes from a patient with long QT syndrome carrying KCNQ1-A344Aspl mutation.
    Wuriyanghai Y; Makiyama T; Sasaki K; Kamakura T; Yamamoto Y; Hayano M; Harita T; Nishiuchi S; Chen J; Kohjitani H; Hirose S; Yokoi F; Gao J; Chonabayashi K; Watanabe K; Ohno S; Yoshida Y; Kimura T; Horie M
    Heart Rhythm; 2018 Oct; 15(10):1566-1574. PubMed ID: 29857160
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cryptic Splice-Altering Variants in
    Lopes LR; Barbosa P; Torrado M; Quinn E; Merino A; Ochoa JP; Jager J; Futema M; Carmo-Fonseca M; Monserrat L; Syrris P; Elliott PM
    Circ Genom Precis Med; 2020 Jun; 13(3):e002905. PubMed ID: 32396390
    [No Abstract]   [Full Text] [Related]  

  • 13. Maturation of hiPSC-derived cardiomyocytes promotes adult alternative splicing of SCN5A and reveals changes in sodium current associated with cardiac arrhythmia.
    Campostrini G; Kosmidis G; Ward-van Oostwaard D; Davis RP; Yiangou L; Ottaviani D; Veerman CC; Mei H; Orlova VV; Wilde AAM; Bezzina CR; Verkerk AO; Mummery CL; Bellin M
    Cardiovasc Res; 2023 Mar; 119(1):167-182. PubMed ID: 35394010
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Divergent effects of adrenaline in human induced pluripotent stem cell-derived cardiomyocytes obtained from hypertrophic cardiomyopathy.
    Prajapati C; Ojala M; Aalto-Setälä K
    Dis Model Mech; 2018 Feb; 11(2):. PubMed ID: 29361520
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hypertrophic cardiomyopathy dysfunction mimicked in human engineered heart tissue and improved by sodium-glucose cotransporter 2 inhibitors.
    Wijnker PJM; Dinani R; van der Laan NC; Algül S; Knollmann BC; Verkerk AO; Remme CA; Zuurbier CJ; Kuster DWD; van der Velden J
    Cardiovasc Res; 2024 Mar; 120(3):301-317. PubMed ID: 38240646
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Advances in Hypertrophic Cardiomyopathy Disease Modelling Using hiPSC-Derived Cardiomyocytes.
    Dababneh S; Hamledari H; Maaref Y; Jayousi F; Hosseini DB; Khan A; Jannati S; Jabbari K; Arslanova A; Butt M; Roston TM; Sanatani S; Tibbits GF
    Can J Cardiol; 2024 May; 40(5):766-776. PubMed ID: 37952715
    [TBL] [Abstract][Full Text] [Related]  

  • 17. iPSC-Based Modeling of Variable Clinical Presentation in Hypertrophic Cardiomyopathy.
    Escribá R; Larrañaga-Moreira JM; Richaud-Patin Y; Pourchet L; Lazis I; Jiménez-Delgado S; Morillas-García A; Ortiz-Genga M; Ochoa JP; Carreras D; Pérez GJ; de la Pompa JL; Brugada R; Monserrat L; Barriales-Villa R; Raya A
    Circ Res; 2023 Jul; 133(2):108-119. PubMed ID: 37317833
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients.
    Wu H; Yang H; Rhee JW; Zhang JZ; Lam CK; Sallam K; Chang ACY; Ma N; Lee J; Zhang H; Blau HM; Bers DM; Wu JC
    Eur Heart J; 2019 Dec; 40(45):3685-3695. PubMed ID: 31219556
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deficient cMyBP-C protein expression during cardiomyocyte differentiation underlies human hypertrophic cardiomyopathy cellular phenotypes in disease specific human ES cell derived cardiomyocytes.
    Monteiro da Rocha A; Guerrero-Serna G; Helms A; Luzod C; Mironov S; Russell M; Jalife J; Day SM; Smith GD; Herron TJ
    J Mol Cell Cardiol; 2016 Oct; 99():197-206. PubMed ID: 27620334
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Spatial and Functional Distribution of
    Helms AS; Thompson AD; Glazier AA; Hafeez N; Kabani S; Rodriguez J; Yob JM; Woolcock H; Mazzarotto F; Lakdawala NK; Wittekind SG; Pereira AC; Jacoby DL; Colan SD; Ashley EA; Saberi S; Ware JS; Ingles J; Semsarian C; Michels M; Olivotto I; Ho CY; Day SM
    Circ Genom Precis Med; 2020 Oct; 13(5):396-405. PubMed ID: 32841044
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.