318 related articles for article (PubMed ID: 33665647)
1. Cathepsin D: A Candidate Link between Amyloid β-protein and Tauopathy in Alzheimer Disease.
Suire CN; Leissring MA
J Exp Neurol; 2021; 2(1):10-15. PubMed ID: 33665647
[TBL] [Abstract][Full Text] [Related]
2. Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: implications for Alzheimer disease pathogenesis.
Terron HM; Parikh SJ; Abdul-Hay SO; Sahara T; Kang D; Dickson DW; Saftig P; LaFerla FM; Lane S; Leissring MA
Alzheimers Res Ther; 2024 Apr; 16(1):70. PubMed ID: 38575959
[TBL] [Abstract][Full Text] [Related]
3. Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: Implications for Alzheimer disease pathogenesis.
Terron HM; Parikh SJ; Abdul-Hay SO; Sahara T; Kang D; Dickson DW; Saftig P; LaFerla FM; Lane S; Leissring MA
Res Sq; 2023 Oct; ():. PubMed ID: 37961253
[TBL] [Abstract][Full Text] [Related]
4. Cathepsin D regulates cerebral Aβ42/40 ratios via differential degradation of Aβ42 and Aβ40.
Suire CN; Abdul-Hay SO; Sahara T; Kang D; Brizuela MK; Saftig P; Dickson DW; Rosenberry TL; Leissring MA
Alzheimers Res Ther; 2020 Jul; 12(1):80. PubMed ID: 32631408
[TBL] [Abstract][Full Text] [Related]
5. Significance of cytosolic cathepsin D in Alzheimer's disease pathology: Protective cellular effects of PLGA nanoparticles against β-amyloid-toxicity.
Wang Y; Wu Q; Anand BG; Karthivashan G; Phukan G; Yang J; Thinakaran G; Westaway D; Kar S
Neuropathol Appl Neurobiol; 2020 Dec; 46(7):686-706. PubMed ID: 32716575
[TBL] [Abstract][Full Text] [Related]
6. Lysosomal cathepsin D is upregulated in Alzheimer's disease neocortex and may be a marker for neurofibrillary degeneration.
Chai YL; Chong JR; Weng J; Howlett D; Halsey A; Lee JH; Attems J; Aarsland D; Francis PT; Chen CP; Lai MKP
Brain Pathol; 2019 Jan; 29(1):63-74. PubMed ID: 30051532
[TBL] [Abstract][Full Text] [Related]
7. Decrease of neuronal FKBP4/FKBP52 modulates perinuclear lysosomal positioning and MAPT/Tau behavior during MAPT/Tau-induced proteotoxic stress.
Chambraud B; Daguinot C; Guillemeau K; Genet M; Dounane O; Meduri G; Poüs C; Baulieu EE; Giustiniani J
Autophagy; 2021 Nov; 17(11):3491-3510. PubMed ID: 33459145
[TBL] [Abstract][Full Text] [Related]
8. Evaluation of Tau Imaging in Staging Alzheimer Disease and Revealing Interactions Between β-Amyloid and Tauopathy.
Wang L; Benzinger TL; Su Y; Christensen J; Friedrichsen K; Aldea P; McConathy J; Cairns NJ; Fagan AM; Morris JC; Ances BM
JAMA Neurol; 2016 Sep; 73(9):1070-7. PubMed ID: 27454922
[TBL] [Abstract][Full Text] [Related]
9. Accumulation of intraneuronal β-amyloid 42 peptides is associated with early changes in microtubule-associated protein 2 in neurites and synapses.
Takahashi RH; Capetillo-Zarate E; Lin MT; Milner TA; Gouras GK
PLoS One; 2013; 8(1):e51965. PubMed ID: 23372648
[TBL] [Abstract][Full Text] [Related]
10. Amyloid-β and tau: the trigger and bullet in Alzheimer disease pathogenesis.
Bloom GS
JAMA Neurol; 2014 Apr; 71(4):505-8. PubMed ID: 24493463
[TBL] [Abstract][Full Text] [Related]
11. Alzheimer's disease.
De-Paula VJ; Radanovic M; Diniz BS; Forlenza OV
Subcell Biochem; 2012; 65():329-52. PubMed ID: 23225010
[TBL] [Abstract][Full Text] [Related]
12. Crocetin promotes clearance of amyloid-β by inducing autophagy via the STK11/LKB1-mediated AMPK pathway.
Wani A; Al Rihani SB; Sharma A; Weadick B; Govindarajan R; Khan SU; Sharma PR; Dogra A; Nandi U; Reddy CN; Bharate SS; Singh G; Bharate SB; Vishwakarma RA; Kaddoumi A; Kumar A
Autophagy; 2021 Nov; 17(11):3813-3832. PubMed ID: 33404280
[TBL] [Abstract][Full Text] [Related]
13. Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion.
Barbero-Camps E; Roca-Agujetas V; Bartolessis I; de Dios C; Fernández-Checa JC; Marí M; Morales A; Hartmann T; Colell A
Autophagy; 2018; 14(7):1129-1154. PubMed ID: 29862881
[TBL] [Abstract][Full Text] [Related]
14. Aβ-induced acceleration of Alzheimer-related τ-pathology spreading and its association with prion protein.
Gomes LA; Hipp SA; Rijal Upadhaya A; Balakrishnan K; Ospitalieri S; Koper MJ; Largo-Barrientos P; Uytterhoeven V; Reichwald J; Rabe S; Vandenberghe R; von Arnim CAF; Tousseyn T; Feederle R; Giudici C; Willem M; Staufenbiel M; Thal DR
Acta Neuropathol; 2019 Dec; 138(6):913-941. PubMed ID: 31414210
[TBL] [Abstract][Full Text] [Related]
15. Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration.
Winton MJ; Lee EB; Sun E; Wong MM; Leight S; Zhang B; Trojanowski JQ; Lee VM
J Neurosci; 2011 May; 31(21):7691-9. PubMed ID: 21613482
[TBL] [Abstract][Full Text] [Related]
16. Diminished parkin solubility and co-localization with intraneuronal amyloid-β are associated with autophagic defects in Alzheimer's disease.
Lonskaya I; Shekoyan AR; Hebron ML; Desforges N; Algarzae NK; Moussa CE
J Alzheimers Dis; 2013; 33(1):231-47. PubMed ID: 22954671
[TBL] [Abstract][Full Text] [Related]
17. Impairment of the autophagy-lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential.
Zhang W; Xu C; Sun J; Shen HM; Wang J; Yang C
Acta Pharm Sin B; 2022 Mar; 12(3):1019-1040. PubMed ID: 35530153
[TBL] [Abstract][Full Text] [Related]
18. Therapeutic potentials of plant iridoids in Alzheimer's and Parkinson's diseases: A review.
Dinda B; Dinda M; Kulsi G; Chakraborty A; Dinda S
Eur J Med Chem; 2019 May; 169():185-199. PubMed ID: 30877973
[TBL] [Abstract][Full Text] [Related]
19. Targeting increased levels of APP in Down syndrome: Posiphen-mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model.
Chen XQ; Salehi A; Pearn ML; Overk C; Nguyen PD; Kleschevnikov AM; Maccecchini M; Mobley WC
Alzheimers Dement; 2021 Feb; 17(2):271-292. PubMed ID: 32975365
[TBL] [Abstract][Full Text] [Related]
20. Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB).
Zheng X; Lin W; Jiang Y; Lu K; Wei W; Huo Q; Cui S; Yang X; Li M; Xu N; Tang C; Song JX
Autophagy; 2021 Nov; 17(11):3833-3847. PubMed ID: 33622188
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]