These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

100 related articles for article (PubMed ID: 33667374)

  • 1. For Whom the Bell Tolls: The Structure of the Dead Kinase, IRAK3.
    Horne CR; Murphy JM
    Structure; 2021 Mar; 29(3):197-199. PubMed ID: 33667374
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dimeric Structure of the Pseudokinase IRAK3 Suggests an Allosteric Mechanism for Negative Regulation.
    Lange SM; Nelen MI; Cohen P; Kulathu Y
    Structure; 2021 Mar; 29(3):238-251.e4. PubMed ID: 33238146
    [TBL] [Abstract][Full Text] [Related]  

  • 3. IRAK3 modulates downstream innate immune signalling through its guanylate cyclase activity.
    Freihat LA; Wheeler JI; Wong A; Turek I; Manallack DT; Irving HR
    Sci Rep; 2019 Oct; 9(1):15468. PubMed ID: 31664109
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of Proteolysis-Targeting Chimera Molecules that Selectively Degrade the IRAK3 Pseudokinase.
    Degorce SL; Tavana O; Banks E; Crafter C; Gingipalli L; Kouvchinov D; Mao Y; Pachl F; Solanki A; Valge-Archer V; Yang B; Edmondson SD
    J Med Chem; 2020 Sep; 63(18):10460-10473. PubMed ID: 32803978
    [TBL] [Abstract][Full Text] [Related]  

  • 5. At Least Two Genes Encode Many Variants of Irak3 in Rainbow Trout, but Neither the Full-Length Factor Nor Its Variants Interfere Directly With the TLR-Mediated Stimulation of Inflammation.
    Rebl A; Rebl H; Verleih M; Haupt S; Köbis JM; Goldammer T; Seyfert HM
    Front Immunol; 2019; 10():2246. PubMed ID: 31616422
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IRAK4 dimerization and trans-autophosphorylation are induced by Myddosome assembly.
    Ferrao R; Zhou H; Shan Y; Liu Q; Li Q; Shaw DE; Li X; Wu H
    Mol Cell; 2014 Sep; 55(6):891-903. PubMed ID: 25201411
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A systematic review and meta-analyses of interleukin-1 receptor associated kinase 3 (IRAK3) action on inflammation in in vivo models for the study of sepsis.
    Nguyen TH; Turek I; Meehan-Andrews T; Zacharias A; Irving HR
    PLoS One; 2022; 17(2):e0263968. PubMed ID: 35167625
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of the interleukin 1 receptor-associated kinase 4 (IRAK4)-encoding gene in salmonid fish: the functional copy is rearranged in Oncorhynchus mykiss and that factor can impair TLR signaling in mammalian cells.
    Brietzke A; Goldammer T; Rebl H; Korytář T; Köllner B; Yang W; Rebl A; Seyfert HM
    Fish Shellfish Immunol; 2014 Jan; 36(1):206-14. PubMed ID: 24239597
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IL-1 receptor-associated kinase-3 acts as an immune checkpoint in myeloid cells to limit cancer immunotherapy.
    Tunalı G; Rúbies Bedós M; Nagarajan D; Fridh P; Papakyriacou I; Mao Y
    J Clin Invest; 2023 Apr; 133(7):. PubMed ID: 36757800
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of human IRAK1.
    Wang L; Qiao Q; Ferrao R; Shen C; Hatcher JM; Buhrlage SJ; Gray NS; Wu H
    Proc Natl Acad Sci U S A; 2017 Dec; 114(51):13507-13512. PubMed ID: 29208712
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting IRAK3 for Degradation to Enhance IL-12 Pro-inflammatory Cytokine Production.
    Rowley A; Brown BS; Stofega M; Hoh H; Mathew R; Marin V; Ding RX; McClure RA; Bittencourt FM; Chen J; Gururaja T; Kinoshita T; Wang X; Rivkin A; Woller KR
    ACS Chem Biol; 2022 Jun; 17(6):1315-1320. PubMed ID: 35580266
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies.
    Bennett J; Starczynowski DT
    Curr Opin Hematol; 2022 Jan; 29(1):8-19. PubMed ID: 34743084
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4).
    Wang L; Ferrao R; Li Q; Hatcher JM; Choi HG; Buhrlage SJ; Gray NS; Wu H
    J Biol Chem; 2019 Mar; 294(12):4511-4519. PubMed ID: 30679311
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional assessment of the mutational effects of human IRAK4 and MyD88 genes.
    Yamamoto T; Tsutsumi N; Tochio H; Ohnishi H; Kubota K; Kato Z; Shirakawa M; Kondo N
    Mol Immunol; 2014 Mar; 58(1):66-76. PubMed ID: 24316379
    [TBL] [Abstract][Full Text] [Related]  

  • 15. IRAK4 in TLR/IL-1R signaling: possible clinical applications.
    Li X
    Eur J Immunol; 2008 Mar; 38(3):614-8. PubMed ID: 18286571
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Blimp-1-Mediated Pathway Promotes Type I IFN Production in Plasmacytoid Dendritic Cells by Targeting to Interleukin-1 Receptor-Associated Kinase M.
    Ko YA; Chan YH; Liu CH; Liang JJ; Chuang TH; Hsueh YP; Lin YL; Lin KI
    Front Immunol; 2018; 9():1828. PubMed ID: 30131810
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism of dysfunction of human variants of the IRAK4 kinase and a role for its kinase activity in interleukin-1 receptor signaling.
    De S; Karim F; Kiessu E; Cushing L; Lin LL; Ghandil P; Hoarau C; Casanova JL; Puel A; Rao VR
    J Biol Chem; 2018 Sep; 293(39):15208-15220. PubMed ID: 30115681
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transduction of Functionally Contrasting Signals by Two Mycobacterial PPE Proteins Downstream of TLR2 Receptors.
    Udgata A; Qureshi R; Mukhopadhyay S
    J Immunol; 2016 Sep; 197(5):1776-87. PubMed ID: 27481848
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Methylation of IRAK3 is a novel prognostic marker in hepatocellular carcinoma.
    Kuo CC; Shih YL; Su HY; Yan MD; Hsieh CB; Liu CY; Huang WT; Yu MH; Lin YW
    World J Gastroenterol; 2015 Apr; 21(13):3960-9. PubMed ID: 25852282
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Clinical IRAK4 deficiency caused by homozygosity for the novel
    Jia A; James E; Lu HY; Sharma M; Modi BP; Biggs CM; Hildebrand KJ; Chomyn A; Erdle S; Kular H; Turvey SE
    Cold Spring Harb Mol Case Stud; 2020 Jun; 6(3):. PubMed ID: 32532880
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.