200 related articles for article (PubMed ID: 33672789)
1. Nrf2 Activation Sensitizes K-Ras Mutant Pancreatic Cancer Cells to Glutaminase Inhibition.
Hamada S; Matsumoto R; Tanaka Y; Taguchi K; Yamamoto M; Masamune A
Int J Mol Sci; 2021 Feb; 22(4):. PubMed ID: 33672789
[TBL] [Abstract][Full Text] [Related]
2. LKB1 and KEAP1/NRF2 Pathways Cooperatively Promote Metabolic Reprogramming with Enhanced Glutamine Dependence in
Galan-Cobo A; Sitthideatphaiboon P; Qu X; Poteete A; Pisegna MA; Tong P; Chen PH; Boroughs LK; Rodriguez MLM; Zhang W; Parlati F; Wang J; Gandhi V; Skoulidis F; DeBerardinis RJ; Minna JD; Heymach JV
Cancer Res; 2019 Jul; 79(13):3251-3267. PubMed ID: 31040157
[TBL] [Abstract][Full Text] [Related]
3. Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma.
Hamada S; Shimosegawa T; Taguchi K; Nabeshima T; Yamamoto M; Masamune A
Am J Physiol Gastrointest Liver Physiol; 2018 Jan; 314(1):G65-G74. PubMed ID: 28971839
[TBL] [Abstract][Full Text] [Related]
4. Simultaneous inhibition of PFKFB3 and GLS1 selectively kills KRAS-transformed pancreatic cells.
Ozcan SC; Mutlu A; Altunok TH; Gurpinar Y; Sarioglu A; Guler S; Muchut RJ; Iglesias AA; Celikler S; Campbell PM; Yalcin A
Biochem Biophys Res Commun; 2021 Sep; 571():118-124. PubMed ID: 34325126
[TBL] [Abstract][Full Text] [Related]
5.
Nabeshima T; Hamada S; Taguchi K; Tanaka Y; Matsumoto R; Yamamoto M; Masamune A
Am J Physiol Gastrointest Liver Physiol; 2020 Mar; 318(3):G419-G427. PubMed ID: 31961719
[TBL] [Abstract][Full Text] [Related]
6. Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
DeNicola GM; Karreth FA; Humpton TJ; Gopinathan A; Wei C; Frese K; Mangal D; Yu KH; Yeo CJ; Calhoun ES; Scrimieri F; Winter JM; Hruban RH; Iacobuzio-Donahue C; Kern SE; Blair IA; Tuveson DA
Nature; 2011 Jul; 475(7354):106-9. PubMed ID: 21734707
[TBL] [Abstract][Full Text] [Related]
7. Undermining Glutaminolysis Bolsters Chemotherapy While NRF2 Promotes Chemoresistance in KRAS-Driven Pancreatic Cancers.
Mukhopadhyay S; Goswami D; Adiseshaiah PP; Burgan W; Yi M; Guerin TM; Kozlov SV; Nissley DV; McCormick F
Cancer Res; 2020 Apr; 80(8):1630-1643. PubMed ID: 31911550
[TBL] [Abstract][Full Text] [Related]
8.
Sitthideatphaiboon P; Galan-Cobo A; Negrao MV; Qu X; Poteete A; Zhang F; Liu DD; Lewis WE; Kemp HN; Lewis J; Rinsurongkawong W; Giri U; Lee JJ; Zhang J; Roth JA; Swisher S; Heymach JV
Clin Cancer Res; 2021 Mar; 27(6):1720-1733. PubMed ID: 33323404
[TBL] [Abstract][Full Text] [Related]
9. Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer.
Elgogary A; Xu Q; Poore B; Alt J; Zimmermann SC; Zhao L; Fu J; Chen B; Xia S; Liu Y; Neisser M; Nguyen C; Lee R; Park JK; Reyes J; Hartung T; Rojas C; Rais R; Tsukamoto T; Semenza GL; Hanes J; Slusher BS; Le A
Proc Natl Acad Sci U S A; 2016 Sep; 113(36):E5328-36. PubMed ID: 27559084
[TBL] [Abstract][Full Text] [Related]
10. Nrf2 promotes mutant K-ras/p53-driven pancreatic carcinogenesis.
Hamada S; Taguchi K; Masamune A; Yamamoto M; Shimosegawa T
Carcinogenesis; 2017 Jun; 38(6):661-670. PubMed ID: 29240881
[TBL] [Abstract][Full Text] [Related]
11. Novel allosteric glutaminase 1 inhibitors with macrocyclic structure activity relationship analysis.
Lee EJ; Duggirala KB; Lee Y; Yun MR; Jang J; Cyriac R; Jung ME; Choi G; Chae CH; Cho BC; Lee K
Bioorg Med Chem Lett; 2022 Nov; 75():128956. PubMed ID: 36038117
[TBL] [Abstract][Full Text] [Related]
12. Nrf2 expression in pancreatic stellate cells promotes progression of cancer.
Tanaka Y; Hamada S; Matsumoto R; Taguchi K; Yamamoto M; Masamune A
Am J Physiol Gastrointest Liver Physiol; 2021 Oct; 321(4):G378-G388. PubMed ID: 34405729
[TBL] [Abstract][Full Text] [Related]
13. The discovery and characterization of K-563, a novel inhibitor of the Keap1/Nrf2 pathway produced by Streptomyces sp.
Hori R; Yamaguchi K; Sato H; Watanabe M; Tsutsumi K; Iwamoto S; Abe M; Onodera H; Nakamura S; Nakai R
Cancer Med; 2019 Mar; 8(3):1157-1168. PubMed ID: 30735010
[TBL] [Abstract][Full Text] [Related]
14. Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy.
Lister A; Nedjadi T; Kitteringham NR; Campbell F; Costello E; Lloyd B; Copple IM; Williams S; Owen A; Neoptolemos JP; Goldring CE; Park BK
Mol Cancer; 2011 Apr; 10():37. PubMed ID: 21489257
[TBL] [Abstract][Full Text] [Related]
15. Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism.
Huang Q; Stalnecker C; Zhang C; McDermott LA; Iyer P; O'Neill J; Reimer S; Cerione RA; Katt WP
J Biol Chem; 2018 Mar; 293(10):3535-3545. PubMed ID: 29317493
[TBL] [Abstract][Full Text] [Related]
16. Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer.
Best SA; Gubser PM; Sethumadhavan S; Kersbergen A; Negrón Abril YL; Goldford J; Sellers K; Abeysekera W; Garnham AL; McDonald JA; Weeden CE; Anderson D; Pirman D; Roddy TP; Creek DJ; Kallies A; Kingsbury G; Sutherland KD
Cell Metab; 2022 Jun; 34(6):874-887.e6. PubMed ID: 35504291
[TBL] [Abstract][Full Text] [Related]
17. Targeting NFE2L2/KEAP1 Mutations in Advanced NSCLC With the TORC1/2 Inhibitor TAK-228.
Paik PK; Fan PD; Qeriqi B; Namakydoust A; Daly B; Ahn L; Kim R; Plodkowski A; Ni A; Chang J; Fanaroff R; Ladanyi M; de Stanchina E; Rudin CM
J Thorac Oncol; 2023 Apr; 18(4):516-526. PubMed ID: 36240971
[TBL] [Abstract][Full Text] [Related]
18. Impact of Nrf2 on tumour growth and drug sensitivity in oncogenic K-ras-transformed cells in vitro and in vivo.
Shao J; Glorieux C; Liao J; Chen P; Lu W; Liang Z; Wen S; Hu Y; Huang P
Free Radic Res; 2018 Jun; 52(6):661-671. PubMed ID: 29621903
[TBL] [Abstract][Full Text] [Related]
19. Mild Oxidative Stress Reduces NRF2 SUMOylation to Promote
Xu J; Guo H; Xing Z; Zhang W; He J; Cheng J; Cai R
Oxid Med Cell Longev; 2020; 2020():6240125. PubMed ID: 33299528
[TBL] [Abstract][Full Text] [Related]
20. Keap1-Nrf2 signalling in pancreatic cancer.
Hayes AJ; Skouras C; Haugk B; Charnley RM
Int J Biochem Cell Biol; 2015 Aug; 65():288-99. PubMed ID: 26117456
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
