222 related articles for article (PubMed ID: 33673002)
1. Microtubule Destabilizing Sulfonamides as an Alternative to Taxane-Based Chemotherapy.
González M; Ovejero-Sánchez M; Vicente-Blázquez A; Álvarez R; Herrero AB; Medarde M; González-Sarmiento R; Peláez R
Int J Mol Sci; 2021 Feb; 22(4):. PubMed ID: 33673002
[TBL] [Abstract][Full Text] [Related]
2. A semisynthetic taxane Yg-3-46a effectively evades P-glycoprotein and β-III tubulin mediated tumor drug resistance in vitro.
Cai P; Lu P; Sharom FJ; Fang WS
Cancer Lett; 2013 Dec; 341(2):214-23. PubMed ID: 23941826
[TBL] [Abstract][Full Text] [Related]
3. New indolesulfonamide derivatives targeting the colchicine site of tubulin: synthesis, anti-tumour activity, structure-activity relationships, and molecular modelling.
Vicente-Blázquez A; González M; Medarde M; Mollinedo F; Peláez R
J Enzyme Inhib Med Chem; 2021 Dec; 36(1):2025-2044. PubMed ID: 34514909
[TBL] [Abstract][Full Text] [Related]
4. Orally bioavailable tubulin antagonists for paclitaxel-refractory cancer.
Li CM; Lu Y; Chen J; Costello TA; Narayanan R; Dalton MN; Snyder LM; Ahn S; Li W; Miller DD; Dalton JT
Pharm Res; 2012 Nov; 29(11):3053-63. PubMed ID: 22760659
[TBL] [Abstract][Full Text] [Related]
5. The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.
Cui YJ; Ma CC; Zhang CM; Tang LQ; Liu ZP
Eur J Med Chem; 2020 Feb; 187():111968. PubMed ID: 31865012
[TBL] [Abstract][Full Text] [Related]
6. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
Eissa IH; Dahab MA; Ibrahim MK; Alsaif NA; Alanazi AZ; Eissa SI; Mehany ABM; Beauchemin AM
Bioorg Chem; 2021 Jul; 112():104965. PubMed ID: 34020238
[TBL] [Abstract][Full Text] [Related]
7. A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule.
Liu ZL; Tian W; Wang Y; Kuang S; Luo XM; Yu Q
Acta Pharmacol Sin; 2012 Feb; 33(2):261-70. PubMed ID: 22301862
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J
Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162
[TBL] [Abstract][Full Text] [Related]
9. Sensitivity of docetaxel-resistant MCF-7 breast cancer cells to microtubule-destabilizing agents including vinca alkaloids and colchicine-site binding agents.
Wang RC; Chen X; Parissenti AM; Joy AA; Tuszynski J; Brindley DN; Wang Z
PLoS One; 2017; 12(8):e0182400. PubMed ID: 28787019
[TBL] [Abstract][Full Text] [Related]
10. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance.
Cheng B; Zhu G; Meng L; Wu G; Chen Q; Ma S
Eur J Med Chem; 2022 Jan; 228():113930. PubMed ID: 34794817
[TBL] [Abstract][Full Text] [Related]
11. Novel amino analogs of the trimethoxyphenyl ring in potent colchicine site ligands improve solubility by the masked polar group incorporation (MPGI) strategy.
González M; Ellahioui Y; Gallego L; Vicente-Blázquez A; Álvarez R; Medarde M; Peláez R
Bioorg Chem; 2023 Feb; 131():106282. PubMed ID: 36459777
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and evaluations of the antiproliferative activity and aqueous solubility of novel carbazole sulfonamide derivatives as antitumor agents.
Sun L; Wang C; Hu X; Wu Y; Jiang Z; Li Z; Chen X; Hu L
Bioorg Chem; 2020 Jun; 99():103766. PubMed ID: 32247110
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis and antiproliferative activity of the new conjugates of E7010 and resveratrol as tubulin polymerization inhibitors.
Kamal A; Ashraf M; Basha ST; Ali Hussaini SM; Singh S; Vishnuvardhan MV; Kiran B; Sridhar B
Org Biomol Chem; 2016 Jan; 14(4):1382-94. PubMed ID: 26676480
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and bioevaluation of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazoles as tubulin polymerization inhibitors.
Liu R; Huang M; Zhang S; Li L; Li M; Sun J; Wu L; Guan Q; Zhang W
Eur J Med Chem; 2021 Dec; 226():113826. PubMed ID: 34571171
[TBL] [Abstract][Full Text] [Related]
15. Multiple mechanisms underlying acquired resistance to taxanes in selected docetaxel-resistant MCF-7 breast cancer cells.
Wang H; Vo T; Hajar A; Li S; Chen X; Parissenti AM; Brindley DN; Wang Z
BMC Cancer; 2014 Jan; 14():37. PubMed ID: 24447372
[TBL] [Abstract][Full Text] [Related]
16. YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivo.
Cai D; Qiu Z; Yao W; Liu Y; Huang H; Liao S; Luo Q; Xie L; Lin Z
Cancer Chemother Pharmacol; 2016 Jun; 77(6):1217-29. PubMed ID: 27107592
[TBL] [Abstract][Full Text] [Related]
17. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
Romagnoli R; Kimatrai Salvador M; Schiaffino Ortega S; Baraldi PG; Oliva P; Baraldi S; Lopez-Cara LC; Brancale A; Ferla S; Hamel E; Balzarini J; Liekens S; Mattiuzzo E; Basso G; Viola G
Eur J Med Chem; 2018 Jan; 143():683-698. PubMed ID: 29220790
[TBL] [Abstract][Full Text] [Related]
18. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.
Yang F; He CP; Diao PC; Hong KH; Rao JJ; Zhao PL
Bioorg Med Chem Lett; 2019 Jan; 29(1):22-27. PubMed ID: 30448234
[TBL] [Abstract][Full Text] [Related]
19. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
Wang YT; Shi TQ; Zhu HL; Liu CH
Bioorg Med Chem; 2019 Feb; 27(3):502-515. PubMed ID: 30606674
[TBL] [Abstract][Full Text] [Related]
20. ELR510444, a novel microtubule disruptor with multiple mechanisms of action.
Risinger AL; Westbrook CD; Encinas A; Mülbaier M; Schultes CM; Wawro S; Lewis JD; Janssen B; Giles FJ; Mooberry SL
J Pharmacol Exp Ther; 2011 Mar; 336(3):652-60. PubMed ID: 21148249
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]