BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

334 related articles for article (PubMed ID: 33673088)

  • 1. Unlocking the Secrets of Cancer Stem Cells with γ-Secretase Inhibitors: A Novel Anticancer Strategy.
    Ghanbari-Movahed M; Ghanbari-Movahed Z; Momtaz S; Kilpatrick KL; Farzaei MH; Bishayee A
    Molecules; 2021 Feb; 26(4):. PubMed ID: 33673088
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In Vitro Evaluation of Clinical Candidates of γ-Secretase Inhibitors: Effects on Notch Inhibition and Promoting Beige Adipogenesis and Mitochondrial Biogenesis.
    Huang D; Qiu J; Kuang S; Deng M
    Pharm Res; 2020 Sep; 37(10):185. PubMed ID: 32888109
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alpha-secretase inhibition reduces human glioblastoma stem cell growth in vitro and in vivo by inhibiting Notch.
    Floyd DH; Kefas B; Seleverstov O; Mykhaylyk O; Dominguez C; Comeau L; Plank C; Purow B
    Neuro Oncol; 2012 Oct; 14(10):1215-26. PubMed ID: 22962413
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gamma-Secretase Inhibitor IX (GSI) Impairs Concomitant Activation of Notch and Wnt-Beta-Catenin Pathways in CD44
    Barat S; Chen X; Cuong Bui K; Bozko P; Götze J; Christgen M; Krech T; Malek NP; Plentz RR
    Stem Cells Transl Med; 2017 Mar; 6(3):819-829. PubMed ID: 28186678
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of Farnesyltransferase Potentiates NOTCH-Targeted Therapy against Glioblastoma Stem Cells.
    Ma Y; Cheng Z; Liu J; Torre-Healy L; Lathia JD; Nakano I; Guo Y; Thompson RC; Freeman ML; Wang J
    Stem Cell Reports; 2017 Dec; 9(6):1948-1960. PubMed ID: 29198824
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.
    Konishi J; Kawaguchi KS; Vo H; Haruki N; Gonzalez A; Carbone DP; Dang TP
    Cancer Res; 2007 Sep; 67(17):8051-7. PubMed ID: 17804716
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gamma Secretase Inhibitors in Cancer: A Current Perspective on Clinical Performance.
    McCaw TR; Inga E; Chen H; Jaskula-Sztul R; Dudeja V; Bibb JA; Ren B; Rose JB
    Oncologist; 2021 Apr; 26(4):e608-e621. PubMed ID: 33284507
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Small molecules that inhibit Notch signaling.
    De Kloe GE; De Strooper B
    Methods Mol Biol; 2014; 1187():311-22. PubMed ID: 25053499
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Blocking the NOTCH pathway can inhibit the growth of CD133-positive A549 cells and sensitize to chemotherapy.
    Liu J; Mao Z; Huang J; Xie S; Liu T; Mao Z
    Biochem Biophys Res Commun; 2014 Feb; 444(4):670-5. PubMed ID: 24502949
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Notch Signaling in Breast Cancer: A Role in Drug Resistance.
    BeLow M; Osipo C
    Cells; 2020 Sep; 9(10):. PubMed ID: 33003540
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rational targeting of Notch signaling in cancer.
    Rizzo P; Osipo C; Foreman K; Golde T; Osborne B; Miele L
    Oncogene; 2008 Sep; 27(38):5124-31. PubMed ID: 18758481
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of Notch signaling pathway using γ-secretase inhibitor delivered by a low dose of Triton-X100 in cultured oral cancer cells.
    Nasrin A; Hassan M; Ye P
    Biochem Biophys Res Commun; 2018 Jan; 495(3):2118-2124. PubMed ID: 29253571
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A high Notch pathway activation predicts response to γ secretase inhibitors in proneural subtype of glioma tumor-initiating cells.
    Saito N; Fu J; Zheng S; Yao J; Wang S; Liu DD; Yuan Y; Sulman EP; Lang FF; Colman H; Verhaak RG; Yung WK; Koul D
    Stem Cells; 2014 Jan; 32(1):301-12. PubMed ID: 24038660
    [TBL] [Abstract][Full Text] [Related]  

  • 14. γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct.
    Ran Y; Hossain F; Pannuti A; Lessard CB; Ladd GZ; Jung JI; Minter LM; Osborne BA; Miele L; Golde TE
    EMBO Mol Med; 2017 Jul; 9(7):950-966. PubMed ID: 28539479
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Atonal homolog 1 is required for growth and differentiation effects of notch/gamma-secretase inhibitors on normal and cancerous intestinal epithelial cells.
    Kazanjian A; Noah T; Brown D; Burkart J; Shroyer NF
    Gastroenterology; 2010 Sep; 139(3):918-28, 928.e1-6. PubMed ID: 20621629
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NOTCH signaling as a novel cancer therapeutic target.
    Miele L; Miao H; Nickoloff BJ
    Curr Cancer Drug Targets; 2006 Jun; 6(4):313-23. PubMed ID: 16848722
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A novel triazole, NMK-T-057, induces autophagic cell death in breast cancer cells by inhibiting γ-secretase-mediated activation of Notch signaling.
    Das A; Narayanam MK; Paul S; Mukhnerjee P; Ghosh S; Dastidar DG; Chakrabarty S; Ganguli A; Basu B; Pal M; Chatterji U; Banerjee SK; Karmakar P; Kumar D; Chakrabarti G
    J Biol Chem; 2019 Apr; 294(17):6733-6750. PubMed ID: 30824542
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of γ-secretase/Notch pathway as a potential therapy for reversing cancer drug resistance.
    Feng M; Santhanam RK; Xing H; Zhou M; Jia H
    Biochem Pharmacol; 2024 Feb; 220():115991. PubMed ID: 38135129
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells.
    Ponnurangam S; Dandawate PR; Dhar A; Tawfik OW; Parab RR; Mishra PD; Ranadive P; Sharma R; Mahajan G; Umar S; Weir SJ; Sugumar A; Jensen RA; Padhye SB; Balakrishnan A; Anant S; Subramaniam D
    Oncotarget; 2016 Jan; 7(3):3217-32. PubMed ID: 26673007
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibiting Notch Activity in Breast Cancer Stem Cells by Glucose Functionalized Nanoparticles Carrying γ-secretase Inhibitors.
    Mamaeva V; Niemi R; Beck M; Özliseli E; Desai D; Landor S; Gronroos T; Kronqvist P; Pettersen IK; McCormack E; Rosenholm JM; Linden M; Sahlgren C
    Mol Ther; 2016 May; 24(5):926-36. PubMed ID: 26916284
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.