BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 33674270)

  • 1. The Long Noncoding RNA Hepatocyte Nuclear Factor 4
    Wang P; Chen S; Wang Y; Wang X; Yan L; Yang K; Zhong XB; Han S; Zhang L
    Drug Metab Dispos; 2021 May; 49(5):361-368. PubMed ID: 33674270
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Long Noncoding RNAs Hepatocyte Nuclear Factor 4A Antisense RNA 1 and Hepatocyte Nuclear Factor 1A Antisense RNA 1 Are Involved in Ritonavir-Induced Cytotoxicity in Hepatoma Cells.
    Wang X; Yu Y; Wang P; Yang K; Wang Y; Yan L; Zhong XB; Zhang L
    Drug Metab Dispos; 2022 May; 50(5):704-715. PubMed ID: 34949673
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The HNF1
    Wang Y; Yan L; Liu J; Chen S; Liu G; Nie Y; Wang P; Yang W; Chen L; Zhong X; Han S; Zhang L
    J Pharmacol Exp Ther; 2019 Mar; 368(3):353-362. PubMed ID: 30602592
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Transcriptional Regulatory Network Containing Nuclear Receptors and Long Noncoding RNAs Controls Basal and Drug-Induced Expression of Cytochrome P450s in HepaRG Cells.
    Chen L; Bao Y; Piekos SC; Zhu K; Zhang L; Zhong XB
    Mol Pharmacol; 2018 Jul; 94(1):749-759. PubMed ID: 29691280
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Knockdown of Long Noncoding RNAs Hepatocyte Nuclear Factor 1
    Chen L; Wang P; Manautou JE; Zhong XB
    Mol Pharmacol; 2020 Apr; 97(4):278-286. PubMed ID: 32029527
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression.
    Li T; Chiang JY
    Drug Metab Dispos; 2006 May; 34(5):756-64. PubMed ID: 16455805
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histone Methyltransferase G9a Regulates Expression of Nuclear Receptors and Cytochrome P450 Enzymes in HepaRG Cells at Basal Level and in Fatty Acid Induced Steatosis.
    Pande P; Zhong XB; Ku WW
    Drug Metab Dispos; 2020 Dec; 48(12):1321-1329. PubMed ID: 33077425
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The far and distal enhancers in the CYP3A4 gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4alpha.
    Liu FJ; Song X; Yang D; Deng R; Yan B
    Biochem J; 2008 Jan; 409(1):243-50. PubMed ID: 17764444
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The long noncoding RNA HNF1A-AS1 with dual functions in the regulation of cytochrome P450 3A4.
    Wang Y; Wang P; Wang Q; Chen S; Wang X; Zhong X; Hu W; Thorne RF; Han S; Wu M; Zhang L
    Biochem Pharmacol; 2024 Feb; 220():116016. PubMed ID: 38176619
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of CYP3A4 expression by ketoconazole is mediated by the disruption of pregnane X receptor, steroid receptor coactivator-1, and hepatocyte nuclear factor 4alpha interaction.
    Lim YP; Kuo SC; Lai ML; Huang JD
    Pharmacogenet Genomics; 2009 Jan; 19(1):11-24. PubMed ID: 19077665
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.
    Tirona RG; Lee W; Leake BF; Lan LB; Cline CB; Lamba V; Parviz F; Duncan SA; Inoue Y; Gonzalez FJ; Schuetz EG; Kim RB
    Nat Med; 2003 Feb; 9(2):220-4. PubMed ID: 12514743
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation of Pregnane X Receptor-Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo.
    Wang F; Wang H; Wu Y; Wang L; Zhang L; Ye X; Peng D; Chen W
    Drug Metab Dispos; 2019 Aug; 47(8):785-793. PubMed ID: 31118196
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lower expression of HNF4α and PGC1α might impair rifampicin-mediated CYP3A4 induction under conditions where PXR is overexpressed in human fetal liver cells.
    Takezawa T; Matsunaga T; Aikawa K; Nakamura K; Ohmori S
    Drug Metab Pharmacokinet; 2012; 27(4):430-8. PubMed ID: 22333269
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alterations of Histone Modifications Contribute to Pregnane X Receptor-Mediated Induction of CYP3A4 by Rifampicin.
    Yan L; Wang Y; Liu J; Nie Y; Zhong XB; Kan Q; Zhang L
    Mol Pharmacol; 2017 Aug; 92(2):113-123. PubMed ID: 28546420
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
    Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
    Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of the aryl hydrocarbon receptor decreases rifampicin-induced CYP3A4 expression in primary human hepatocytes and HepaRG.
    Rasmussen MK; Daujat-Chavanieu M; Gerbal-Chaloin S
    Toxicol Lett; 2017 Aug; 277():1-8. PubMed ID: 28571685
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel mechanisms of regulation of the expression and transcriptional activity of hepatocyte nuclear factor 4α.
    Guo S; Lu H
    J Cell Biochem; 2019 Jan; 120(1):519-532. PubMed ID: 30191603
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation.
    Dvorak Z; Modriansky M; Pichard-Garcia L; Balaguer P; Vilarem MJ; Ulrichová J; Maurel P; Pascussi JM
    Mol Pharmacol; 2003 Jul; 64(1):160-9. PubMed ID: 12815172
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Positive and negative regulation of human hepatic hydroxysteroid sulfotransferase (SULT2A1) gene transcription by rifampicin: roles of hepatocyte nuclear factor 4alpha and pregnane X receptor.
    Fang HL; Strom SC; Ellis E; Duanmu Z; Fu J; Duniec-Dmuchowski Z; Falany CN; Falany JL; Kocarek TA; Runge-Morris M
    J Pharmacol Exp Ther; 2007 Nov; 323(2):586-98. PubMed ID: 17687072
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.
    Westerink WM; Schoonen WG
    Toxicol In Vitro; 2007 Dec; 21(8):1581-91. PubMed ID: 17637504
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.