BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 33674449)

  • 1. DNAJB chaperones suppress destabilised protein aggregation via a region distinct from that used to inhibit amyloidogenesis.
    McMahon S; Bergink S; Kampinga HH; Ecroyd H
    J Cell Sci; 2021 Apr; 134(7):. PubMed ID: 33674449
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptides.
    Gillis J; Schipper-Krom S; Juenemann K; Gruber A; Coolen S; van den Nieuwendijk R; van Veen H; Overkleeft H; Goedhart J; Kampinga HH; Reits EA
    J Biol Chem; 2013 Jun; 288(24):17225-37. PubMed ID: 23612975
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation.
    Hageman J; Rujano MA; van Waarde MA; Kakkar V; Dirks RP; Govorukhina N; Oosterveld-Hut HM; Lubsen NH; Kampinga HH
    Mol Cell; 2010 Feb; 37(3):355-69. PubMed ID: 20159555
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulatory inter-domain interactions influence Hsp70 recruitment to the DnaJB8 chaperone.
    Ryder BD; Matlahov I; Bali S; Vaquer-Alicea J; van der Wel PCA; Joachimiak LA
    Nat Commun; 2021 Feb; 12(1):946. PubMed ID: 33574241
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNAJB6 is a peptide-binding chaperone which can suppress amyloid fibrillation of polyglutamine peptides at substoichiometric molar ratios.
    Månsson C; Kakkar V; Monsellier E; Sourigues Y; Härmark J; Kampinga HH; Melki R; Emanuelsson C
    Cell Stress Chaperones; 2014 Mar; 19(2):227-39. PubMed ID: 23904097
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interaction of the molecular chaperone DNAJB6 with growing amyloid-beta 42 (Aβ42) aggregates leads to sub-stoichiometric inhibition of amyloid formation.
    Månsson C; Arosio P; Hussein R; Kampinga HH; Hashem RM; Boelens WC; Dobson CM; Knowles TP; Linse S; Emanuelsson C
    J Biol Chem; 2014 Nov; 289(45):31066-76. PubMed ID: 25217638
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Versatile members of the DNAJ family show Hsp70 dependent anti-aggregation activity on RING1 mutant parkin C289G.
    Kakkar V; Kuiper EF; Pandey A; Braakman I; Kampinga HH
    Sci Rep; 2016 Oct; 6():34830. PubMed ID: 27713507
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Using bicistronic constructs to evaluate the chaperone activities of heat shock proteins in cells.
    San Gil R; Berg T; Ecroyd H
    Sci Rep; 2017 May; 7(1):2387. PubMed ID: 28539657
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates.
    Yue HW; Hong JY; Zhang SX; Jiang LL; Hu HY
    Sci Rep; 2021 Apr; 11(1):7815. PubMed ID: 33837238
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Intercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal level.
    Takeuchi T; Suzuki M; Fujikake N; Popiel HA; Kikuchi H; Futaki S; Wada K; Nagai Y
    Proc Natl Acad Sci U S A; 2015 May; 112(19):E2497-506. PubMed ID: 25918398
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities.
    Hageman J; van Waarde MA; Zylicz A; Walerych D; Kampinga HH
    Biochem J; 2011 Apr; 435(1):127-42. PubMed ID: 21231916
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human DnaJB6 Antiamyloid Chaperone Protects Yeast from Polyglutamine Toxicity Separately from Spatial Segregation of Aggregates.
    Kumar J; Kline NL; Masison DC
    Mol Cell Biol; 2018 Dec; 38(23):. PubMed ID: 30224519
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyloid-β oligomers are captured by the DNAJB6 chaperone: Direct detection of interactions that can prevent primary nucleation.
    Österlund N; Lundqvist M; Ilag LL; Gräslund A; Emanuelsson C
    J Biol Chem; 2020 Jun; 295(24):8135-8144. PubMed ID: 32350108
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation.
    Månsson C; van Cruchten RTP; Weininger U; Yang X; Cukalevski R; Arosio P; Dobson CM; Knowles T; Akke M; Linse S; Emanuelsson C
    Biochemistry; 2018 Aug; 57(32):4891-4902. PubMed ID: 30024736
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multi-Faceted Roles of DNAJB Protein in Cancer Metastasis and Clinical Implications.
    Kim HY; Hong S
    Int J Mol Sci; 2022 Nov; 23(23):. PubMed ID: 36499297
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNAJB6 mutants display toxic gain of function through unregulated interaction with Hsp70 chaperones.
    Abayev-Avraham M; Salzberg Y; Gliksberg D; Oren-Suissa M; Rosenzweig R
    Nat Commun; 2023 Nov; 14(1):7066. PubMed ID: 37923706
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The HSP40 family chaperone isoform DNAJB6b prevents neuronal cells from tau aggregation.
    Chang YL; Yang CC; Huang YY; Chen YA; Yang CW; Liao CY; Li H; Wu CS; Lin CH; Teng SC
    BMC Biol; 2023 Dec; 21(1):293. PubMed ID: 38110916
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Extracellular chaperone networks and the export of J-domain proteins.
    Braun JEA
    J Biol Chem; 2023 Feb; 299(2):102840. PubMed ID: 36581212
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HSP40 proteins use class-specific regulation to drive HSP70 functional diversity.
    Faust O; Abayev-Avraham M; Wentink AS; Maurer M; Nillegoda NB; London N; Bukau B; Rosenzweig R
    Nature; 2020 Nov; 587(7834):489-494. PubMed ID: 33177718
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Co-chaperones DNAJA1 and DNAJB6 are critical for regulation of polyglutamine aggregation.
    Rodríguez-González C; Lin S; Arkan S; Hansen C
    Sci Rep; 2020 May; 10(1):8130. PubMed ID: 32424160
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.