BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

270 related articles for article (PubMed ID: 33676893)

  • 1. The phosphorylation of the Smad2/3 linker region by nemo-like kinase regulates TGF-β signaling.
    Liang J; Zhou Y; Zhang N; Wang D; Cheng X; Li K; Huang R; Lu Y; Wang H; Han D; Wu W; Han M; Miao S; Wang L; Zhao H; Song W
    J Biol Chem; 2021; 296():100512. PubMed ID: 33676893
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-beta signaling.
    Wrighton KH; Willis D; Long J; Liu F; Lin X; Feng XH
    J Biol Chem; 2006 Dec; 281(50):38365-75. PubMed ID: 17035229
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transforming growth factor-β signalling: role and consequences of Smad linker region phosphorylation.
    Kamato D; Burch ML; Piva TJ; Rezaei HB; Rostam MA; Xu S; Zheng W; Little PJ; Osman N
    Cell Signal; 2013 Oct; 25(10):2017-24. PubMed ID: 23770288
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interleukin 1 β-induced SMAD2/3 linker modifications are TAK1 dependent and delay TGFβ signaling in primary human mesenchymal stem cells.
    van den Akker GG; van Beuningen HM; Vitters EL; Koenders MI; van de Loo FA; van Lent PL; Blaney Davidson EN; van der Kraan PM
    Cell Signal; 2017 Dec; 40():190-199. PubMed ID: 28943409
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.
    Matsuzaki K; Kitano C; Murata M; Sekimoto G; Yoshida K; Uemura Y; Seki T; Taketani S; Fujisawa J; Okazaki K
    Cancer Res; 2009 Jul; 69(13):5321-30. PubMed ID: 19531654
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins.
    Nakano A; Koinuma D; Miyazawa K; Uchida T; Saitoh M; Kawabata M; Hanai J; Akiyama H; Abe M; Miyazono K; Matsumoto T; Imamura T
    J Biol Chem; 2009 Mar; 284(10):6109-15. PubMed ID: 19122240
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling.
    Gao S; Alarcón C; Sapkota G; Rahman S; Chen PY; Goerner N; Macias MJ; Erdjument-Bromage H; Tempst P; Massagué J
    Mol Cell; 2009 Nov; 36(3):457-68. PubMed ID: 19917253
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential role of Sloan-Kettering Institute (Ski) protein in Nodal and transforming growth factor-beta (TGF-β)-induced Smad signaling in prostate cancer cells.
    Vo BT; Cody B; Cao Y; Khan SA
    Carcinogenesis; 2012 Nov; 33(11):2054-64. PubMed ID: 22843506
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pin1 promotes transforming growth factor-beta-induced migration and invasion.
    Matsuura I; Chiang KN; Lai CY; He D; Wang G; Ramkumar R; Uchida T; Ryo A; Lu K; Liu F
    J Biol Chem; 2010 Jan; 285(3):1754-64. PubMed ID: 19920136
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fibroblast-specific TGF-β-Smad2/3 signaling underlies cardiac fibrosis.
    Khalil H; Kanisicak O; Prasad V; Correll RN; Fu X; Schips T; Vagnozzi RJ; Liu R; Huynh T; Lee SJ; Karch J; Molkentin JD
    J Clin Invest; 2017 Oct; 127(10):3770-3783. PubMed ID: 28891814
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Osteoarthritis-Related Inflammation Blocks TGF-β's Protective Effect on Chondrocyte Hypertrophy via (de)Phosphorylation of the SMAD2/3 Linker Region.
    Thielen N; Neefjes M; Wiegertjes R; van den Akker G; Vitters E; van Beuningen H; Blaney Davidson E; Koenders M; van Lent P; van de Loo F; van Caam A; van der Kraan P
    Int J Mol Sci; 2021 Jul; 22(15):. PubMed ID: 34360888
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transforming growth factor β-mediated site-specific Smad linker region phosphorylation in vascular endothelial cells.
    Kamato D; Rostam MA; Piva TJ; Babaahmadi Rezaei H; Getachew R; Thach L; Bernard R; Zheng W; Little PJ; Osman N
    J Pharm Pharmacol; 2014 Dec; 66(12):1722-33. PubMed ID: 25316549
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling.
    Brown KA; Pietenpol JA; Moses HL
    J Cell Biochem; 2007 May; 101(1):9-33. PubMed ID: 17340614
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clusterin, a novel modulator of TGF-beta signaling, is involved in Smad2/3 stability.
    Lee KB; Jeon JH; Choi I; Kwon OY; Yu K; You KH
    Biochem Biophys Res Commun; 2008 Feb; 366(4):905-9. PubMed ID: 18082619
    [TBL] [Abstract][Full Text] [Related]  

  • 15. WDR74 functions as a novel coactivator in TGF-β signaling.
    Liu J; Zhao M; Yuan B; Gu S; Zheng M; Zou J; Jin J; Liu T; Feng XH
    J Genet Genomics; 2018 Dec; 45(12):639-650. PubMed ID: 30594465
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cell biology of Smad2/3 linker region phosphorylation in vascular smooth muscle.
    Rezaei HB; Kamato D; Ansari G; Osman N; Little PJ
    Clin Exp Pharmacol Physiol; 2012 Aug; 39(8):661-7. PubMed ID: 21883378
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Salvianolic acid B exerts anti-liver fibrosis effects via inhibition of MAPK-mediated phospho-Smad2/3 at linker regions in vivo and in vitro.
    Wu C; Chen W; Ding H; Li D; Wen G; Zhang C; Lu W; Chen M; Yang Y
    Life Sci; 2019 Dec; 239():116881. PubMed ID: 31678285
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of TGF-β signaling at the nuclear envelope: characterization of interactions between MAN1, Smad2 and Smad3, and PPM1A.
    Bourgeois B; Gilquin B; Tellier-Lebègue C; Östlund C; Wu W; Pérez J; El Hage P; Lallemand F; Worman HJ; Zinn-Justin S
    Sci Signal; 2013 Jun; 6(280):ra49. PubMed ID: 23779087
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions.
    Itoh F; Itoh S; Adachi T; Ichikawa K; Matsumura Y; Takagi T; Festing M; Watanabe T; Weinstein M; Karlsson S; Kato M
    Blood; 2012 May; 119(22):5320-8. PubMed ID: 22498737
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kaurenoic acid activates TGF-β signaling.
    Kim KH; Han JW; Jung SK; Park BJ; Han CW; Joo M
    Phytomedicine; 2017 Aug; 32():8-14. PubMed ID: 28732811
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.