BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 33679774)

  • 1. Identification of Novel Genetic Regulatory Region for Proprotein Convertase FURIN and Interferon Gamma in T Cells.
    Ortutay Z; Grönholm A; Laitinen M; Keresztes-Andrei M; Hermelo I; Pesu M
    Front Immunol; 2021; 12():630389. PubMed ID: 33679774
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Proprotein convertase furin is preferentially expressed in T helper 1 cells and regulates interferon gamma.
    Pesu M; Muul L; Kanno Y; O'Shea JJ
    Blood; 2006 Aug; 108(3):983-5. PubMed ID: 16627761
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proprotein convertase FURIN constrains Th2 differentiation and is critical for host resistance against Toxoplasma gondii.
    Oksanen A; Aittomäki S; Jankovic D; Ortutay Z; Pulkkinen K; Hämäläinen S; Rokka A; Corthals GL; Watford WT; Junttila I; O'Shea JJ; Pesu M
    J Immunol; 2014 Dec; 193(11):5470-9. PubMed ID: 25355923
    [TBL] [Abstract][Full Text] [Related]  

  • 4. T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance.
    Pesu M; Watford WT; Wei L; Xu L; Fuss I; Strober W; Andersson J; Shevach EM; Quezado M; Bouladoux N; Roebroek A; Belkaid Y; Creemers J; O'Shea JJ
    Nature; 2008 Sep; 455(7210):246-50. PubMed ID: 18701887
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loss of the proprotein convertase Furin in T cells represses mammary tumorigenesis in oncogene-driven triple negative breast cancer.
    He Z; Khatib AM; Creemers JWM
    Cancer Lett; 2020 Aug; 484():40-49. PubMed ID: 32389711
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proprotein convertase enzyme FURIN is upregulated in primary Sjögren's syndrome.
    Ranta N; Valli A; Grönholm A; Silvennoinen O; Isomäki P; Pesu M; Pertovaara M
    Clin Exp Rheumatol; 2018; 36 Suppl 112(3):47-50. PubMed ID: 29465367
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1: impact on the bioactivation of proproteins.
    McMahon S; Grondin F; McDonald PP; Richard DE; Dubois CM
    J Biol Chem; 2005 Feb; 280(8):6561-9. PubMed ID: 15611046
    [TBL] [Abstract][Full Text] [Related]  

  • 8. T-cell-expressed proprotein convertase FURIN inhibits DMBA/TPA-induced skin cancer development.
    Vähätupa M; Aittomäki S; Martinez Cordova Z; May U; Prince S; Uusitalo-Järvinen H; Järvinen TA; Pesu M
    Oncoimmunology; 2016; 5(12):e1245266. PubMed ID: 28123881
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Myeloid cell expressed proprotein convertase FURIN attenuates inflammation.
    Cordova ZM; Grönholm A; Kytölä V; Taverniti V; Hämäläinen S; Aittomäki S; Niininen W; Junttila I; Ylipää A; Nykter M; Pesu M
    Oncotarget; 2016 Aug; 7(34):54392-54404. PubMed ID: 27527873
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells.
    Penix L; Weaver WM; Pang Y; Young HA; Wilson CB
    J Exp Med; 1993 Nov; 178(5):1483-96. PubMed ID: 8228802
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Proprotein convertase FURIN regulates T cell receptor-induced transactivation.
    Ortutay Z; Oksanen A; Aittomäki S; Ortutay C; Pesu M
    J Leukoc Biol; 2015 Jul; 98(1):73-83. PubMed ID: 25926688
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sox9-dependent transcriptional regulation of the proprotein convertase furin.
    Guimont P; Grondin F; Dubois CM
    Am J Physiol Cell Physiol; 2007 Jul; 293(1):C172-83. PubMed ID: 17360815
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release.
    Narita T; Ito S; Higashijima Y; Chu WK; Neumann K; Walter J; Satpathy S; Liebner T; Hamilton WB; Maskey E; Prus G; Shibata M; Iesmantavicius V; Brickman JM; Anastassiadis K; Koseki H; Choudhary C
    Mol Cell; 2021 May; 81(10):2166-2182.e6. PubMed ID: 33765415
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Polyphenols with indirect proprotein convertase inhibitory activity.
    Zhu J; Van de Ven W; Vermorken A
    Int J Oncol; 2013 Sep; 43(3):947-55. PubMed ID: 23835774
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ectopically expressed pro-group X secretory phospholipase A2 is proteolytically activated in mouse adrenal cells by furin-like proprotein convertases: implications for the regulation of adrenal steroidogenesis.
    Layne JD; Shridas P; Webb NR
    J Biol Chem; 2015 Mar; 290(12):7851-60. PubMed ID: 25623068
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Establishment of proprotein convertase, furinA knocked-out lines in medaka, Oryzias latipes, and unique form of medaka furin-like prorprotein convertase (mflPC).
    Murata K; Kinoshita M
    Comp Biochem Physiol C Toxicol Pharmacol; 2015 Dec; 178():169-180. PubMed ID: 26475985
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thrombin activation of protein C requires prior processing by a liver proprotein convertase.
    Essalmani R; Susan-Resiga D; Guillemot J; Kim W; Sachan V; Awan Z; Chamberland A; Asselin MC; Ly K; Desjardins R; Day R; Prat A; Seidah NG
    J Biol Chem; 2017 Jun; 292(25):10564-10573. PubMed ID: 28468828
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure.
    Turpeinen H; Seppälä I; Lyytikäinen LP; Raitoharju E; Hutri-Kähönen N; Levula M; Oksala N; Waldenberger M; Klopp N; Illig T; Mononen N; Laaksonen R; Raitakari O; Kähönen M; Lehtimäki T; Pesu M
    Hum Genet; 2015 Jun; 134(6):627-36. PubMed ID: 25813623
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A distal enhancer in the interferon-gamma (IFN-gamma) locus revealed by genome sequence comparison.
    Lee DU; Avni O; Chen L; Rao A
    J Biol Chem; 2004 Feb; 279(6):4802-10. PubMed ID: 14607827
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A distal region in the interferon-gamma gene is a site of epigenetic remodeling and transcriptional regulation by interleukin-2.
    Bream JH; Hodge DL; Gonsky R; Spolski R; Leonard WJ; Krebs S; Targan S; Morinobu A; O'Shea JJ; Young HA
    J Biol Chem; 2004 Sep; 279(39):41249-57. PubMed ID: 15271977
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.