These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

107 related articles for article (PubMed ID: 33682244)

  • 21. Substrate interaction dynamics and oxygen control in the active site of thymidylate synthase ThyX.
    Becker HF; Djaout K; Lamarre I; Ulmer JE; Schaming D; Balland V; Liebl U; Myllykallio H; Vos MH
    Biochem J; 2014 Apr; 459(1):37-45. PubMed ID: 24422556
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Asparagine 229 mutants of thymidylate synthase catalyze the methylation of 3-methyl-2'-deoxyuridine 5'-monophosphate.
    Costi PM; Liu L; Finer-Moore JS; Stroud RM; Santi DV
    Biochemistry; 1996 Apr; 35(13):3944-9. PubMed ID: 8672425
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Biochemical determinants of 5-fluorouracil response in vivo. The role of deoxyuridylate pool expansion.
    Myers CE; Young RC; Chabner BA
    J Clin Invest; 1975 Nov; 56(5):1231-8. PubMed ID: 1184747
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and evaluation of 6-aza-2'-deoxyuridine monophosphate analogs as inhibitors of thymidylate synthases, and as substrates or inhibitors of thymidine monophosphate kinase in Mycobacterium tuberculosis.
    Kögler M; Busson R; De Jonghe S; Rozenski J; Van Belle K; Louat T; Munier-Lehmann H; Herdewijn P
    Chem Biodivers; 2012 Mar; 9(3):536-56. PubMed ID: 22422522
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Effect of halogen substitutions on dUMP to stability of thymidylate synthase/dUMP/mTHF ternary complex using molecular dynamics simulation.
    Kaiyawet N; Rungrotmongkol T; Hannongbua S
    J Chem Inf Model; 2013 Jun; 53(6):1315-23. PubMed ID: 23705822
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Structural and functional roles of dynamically correlated residues in thymidylate kinase.
    Chaudhary SK; Jeyakanthan J; Sekar K
    Acta Crystallogr D Struct Biol; 2018 Apr; 74(Pt 4):341-354. PubMed ID: 29652261
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Contribution of a salt bridge to binding affinity and dUMP orientation to catalytic rate: mutation of a substrate-binding arginine in thymidylate synthase.
    Finer-Moore JS; Fauman EB; Morse RJ; Santi DV; Stroud RM
    Protein Eng; 1996 Jan; 9(1):69-75. PubMed ID: 9053905
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A stable binary complex between Leishmania major thymidylate synthase and the substrate deoxyuridylate. A slow-binding interaction.
    Garvey EP; Santi DV
    J Biol Chem; 1987 Jul; 262(19):9068-74. PubMed ID: 3597407
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The structural basis of unique substrate recognition by Plasmodium thymidylate kinase: Molecular dynamics simulation and inhibitory studies.
    Kandeel M; Kitade Y; Al-Taher A; Al-Nazawi M
    PLoS One; 2019; 14(2):e0212065. PubMed ID: 30730992
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Effects of subunit occupancy on partitioning of an intermediate in thymidylate synthase mutants.
    Variath P; Liu Y; Lee TT; Stroud RM; Santi DV
    Biochemistry; 2000 Mar; 39(10):2429-35. PubMed ID: 10704192
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Relationship of dUMP and free FdUMP pools to inhibition of thymidylate synthase by 5-fluorouracil.
    Berger SH; Hakala MT
    Mol Pharmacol; 1984 Mar; 25(2):303-9. PubMed ID: 6608049
    [TBL] [Abstract][Full Text] [Related]  

  • 32. 5-Substituted 2'-deoxyuridines: correlation between inhibition of tumor cell growth and inhibition of thymidine kinase and thymidylate synthetase.
    Balzarini J; De Clercq E; Mertes MP; Shugar D; Torrence PF
    Biochem Pharmacol; 1982 Nov; 31(22):3673-82. PubMed ID: 7181950
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Backbone and ILVM methyl resonance assignments of human thymidylate synthase in apo and substrate bound forms.
    Bonin JP; Lee AL
    Biomol NMR Assign; 2021 Apr; 15(1):197-202. PubMed ID: 33486616
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Crystal structure of the active form of native human thymidylate synthase in the absence of bound substrates.
    Deschamps P; Réty S; Bareille J; Leulliot N
    Acta Crystallogr F Struct Biol Commun; 2017 Jun; 73(Pt 6):336-341. PubMed ID: 28580921
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Human thymidylate synthetase derived from blast cells of patients with acture myelocytic leukemia. Purification and chracterization.
    Dolnick BJ; Cheng Yc
    J Biol Chem; 1977 Nov; 252(21):7697-703. PubMed ID: 269853
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Purification and partial characterization of a putative thymidylate synthase from Methanobacterium thermoautotrophicum.
    Krone UE; McFarlan SC; Hogenkamp HP
    Eur J Biochem; 1994 Mar; 220(3):789-94. PubMed ID: 8143733
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Chimeric polypeptide of thymidine kinase and thymidylate kinase of shrimp white spot syndrome virus: thymidine kinase activity of the recombinant protein expressed in a baculovirus/insect cell system.
    Tzeng HF; Chang ZF; Peng SE; Wang CH; Lin JY; Kou GH; Lo CF
    Virology; 2002 Aug; 299(2):248-55. PubMed ID: 12202227
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Ligand-induced conformational changes of thymidylate synthase detected by limited proteolysis.
    Mohsen AW; Aull JL; Payne DM; Daron HH
    Biochemistry; 1995 Feb; 34(5):1669-77. PubMed ID: 7849026
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Inhibition of mammalian tumour thymidylate synthetase by 2'-deoxyuridine 5'-phosphate analogues.
    Rode W; Kulikowski T; Kedzierska B; Shugar D
    Drugs Exp Clin Res; 1986; 12(6-7):545-9. PubMed ID: 3743372
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Simple separation of tritiated water and [3H]deoxyuridine from [5-3H]deoxyuridine 5'-monophosphate in the thymidylate synthase assay.
    Hashimoto Y; Shiotani T; Weber G
    Anal Biochem; 1987 Dec; 167(2):340-6. PubMed ID: 3442329
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.