255 related articles for article (PubMed ID: 33683200)
1. Structural basis for human TRPC5 channel inhibition by two distinct inhibitors.
Song K; Wei M; Guo W; Quan L; Kang Y; Wu JX; Chen L
Elife; 2021 Mar; 10():. PubMed ID: 33683200
[TBL] [Abstract][Full Text] [Related]
2. Clemizole hydrochloride is a novel and potent inhibitor of transient receptor potential channel TRPC5.
Richter JM; Schaefer M; Hill K
Mol Pharmacol; 2014 Nov; 86(5):514-21. PubMed ID: 25140002
[TBL] [Abstract][Full Text] [Related]
3. Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice.
Just S; Chenard BL; Ceci A; Strassmaier T; Chong JA; Blair NT; Gallaschun RJ; Del Camino D; Cantin S; D'Amours M; Eickmeier C; Fanger CM; Hecker C; Hessler DP; Hengerer B; Kroker KS; Malekiani S; Mihalek R; McLaughlin J; Rast G; Witek J; Sauer A; Pryce CR; Moran MM
PLoS One; 2018; 13(1):e0191225. PubMed ID: 29385160
[TBL] [Abstract][Full Text] [Related]
4. Cryo-EM structure of TRPC5 at 2.8-Å resolution reveals unique and conserved structural elements essential for channel function.
Duan J; Li J; Chen GL; Ge Y; Liu J; Xie K; Peng X; Zhou W; Zhong J; Zhang Y; Xu J; Xue C; Liang B; Zhu L; Liu W; Zhang C; Tian XL; Wang J; Clapham DE; Zeng B; Li Z; Zhang J
Sci Adv; 2019 Jul; 5(7):eaaw7935. PubMed ID: 31355338
[TBL] [Abstract][Full Text] [Related]
5. Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels.
Zhu Y; Lu Y; Qu C; Miller M; Tian J; Thakur DP; Zhu J; Deng Z; Hu X; Wu M; McManus OB; Li M; Hong X; Zhu MX; Luo HR
Br J Pharmacol; 2015 Jul; 172(14):3495-509. PubMed ID: 25816897
[TBL] [Abstract][Full Text] [Related]
6. A greasy business: Identification of a diacylglycerol binding site in human TRPC5 channels by cryo-EM.
Storch U; Mederos Y Schnitzler M; Gudermann T
Cell Calcium; 2021 Apr; 97():102414. PubMed ID: 33930818
[TBL] [Abstract][Full Text] [Related]
7. High resolution cryo-EM structures of TRPC5-Gα
Zhu MX
Cell Calcium; 2023 Jul; 113():102767. PubMed ID: 37321139
[TBL] [Abstract][Full Text] [Related]
8. Stereo-selective inhibition of transient receptor potential TRPC5 cation channels by neuroactive steroids.
Majeed Y; Amer MS; Agarwal AK; McKeown L; Porter KE; O'Regan DJ; Naylor J; Fishwick CW; Muraki K; Beech DJ
Br J Pharmacol; 2011 Apr; 162(7):1509-20. PubMed ID: 21108630
[TBL] [Abstract][Full Text] [Related]
9. Activation of TRPC cationic channels by mercurial compounds confers the cytotoxicity of mercury exposure.
Xu SZ; Zeng B; Daskoulidou N; Chen GL; Atkin SL; Lukhele B
Toxicol Sci; 2012 Jan; 125(1):56-68. PubMed ID: 21984481
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903.
Sharma SH; Pablo JL; Montesinos MS; Greka A; Hopkins CR
Bioorg Med Chem Lett; 2019 Jan; 29(2):155-159. PubMed ID: 30538066
[TBL] [Abstract][Full Text] [Related]
11. Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site.
Wright DJ; Simmons KJ; Johnson RM; Beech DJ; Muench SP; Bon RS
Commun Biol; 2020 Nov; 3(1):704. PubMed ID: 33230284
[TBL] [Abstract][Full Text] [Related]
12. PIP
Ningoo M; Plant LD; Greka A; Logothetis DE
J Biol Chem; 2021; 296():100726. PubMed ID: 33933453
[TBL] [Abstract][Full Text] [Related]
13. Activity dependent inhibition of TRPC1/4/5 channels by duloxetine involves voltage sensor-like domain.
Zimova L; Ptakova A; Mitro M; Krusek J; Vlachova V
Biomed Pharmacother; 2022 Aug; 152():113262. PubMed ID: 35691156
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and Characterization of a Specific Iodine-125-Labeled TRPC5 Radioligand.
Yu Y; Liang Q; Du L; Jiang H; Gu J; Hu H; Tu Z
ChemMedChem; 2020 Oct; 15(19):1854-1860. PubMed ID: 32717096
[TBL] [Abstract][Full Text] [Related]
15. A benzothiadiazine derivative and methylprednisolone are novel and selective activators of transient receptor potential canonical 5 (TRPC5) channels.
Beckmann H; Richter J; Hill K; Urban N; Lemoine H; Schaefer M
Cell Calcium; 2017 Sep; 66():10-18. PubMed ID: 28807145
[TBL] [Abstract][Full Text] [Related]
16. Molecular determinants of PKA-dependent inhibition of TRPC5 channel.
Sung TS; Jeon JP; Kim BJ; Hong C; Kim SY; Kim J; Jeon JH; Kim HJ; Suh CK; Kim SJ; So I
Am J Physiol Cell Physiol; 2011 Oct; 301(4):C823-32. PubMed ID: 21734191
[TBL] [Abstract][Full Text] [Related]
17. The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5.
Miehe S; Bieberstein A; Arnould I; Ihdene O; Rütten H; Strübing C
J Biol Chem; 2010 Apr; 285(16):12426-34. PubMed ID: 20164195
[TBL] [Abstract][Full Text] [Related]
18. TRPC5.
Zholos AV
Handb Exp Pharmacol; 2014; 222():129-56. PubMed ID: 24756705
[TBL] [Abstract][Full Text] [Related]
19. Structural and accessibility studies highlight the differential binding of clemizole to TRPC5 and TRPC6.
Saqib U; Demaree IS; Obukhov AG; Baig MS; Khan MS; Altwaijry N; Nasution MAF; Mizuguchi K; Hajela K
J Biomol Struct Dyn; 2024 Jan; ():1-14. PubMed ID: 38279926
[TBL] [Abstract][Full Text] [Related]
20. TRPC1 as a negative regulator for TRPC4 and TRPC5 channels.
Kim J; Ko J; Myeong J; Kwak M; Hong C; So I
Pflugers Arch; 2019 Aug; 471(8):1045-1053. PubMed ID: 31222490
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]