184 related articles for article (PubMed ID: 33685480)
1. Pexidartinib treatment in Alexander disease model mice reduces macrophage numbers and increases glial fibrillary acidic protein levels, yet has minimal impact on other disease phenotypes.
Boyd MM; Litscher SJ; Seitz LL; Messing A; Hagemann TL; Collier LS
J Neuroinflammation; 2021 Mar; 18(1):67. PubMed ID: 33685480
[TBL] [Abstract][Full Text] [Related]
2. Suppression of GFAP toxicity by alphaB-crystallin in mouse models of Alexander disease.
Hagemann TL; Boelens WC; Wawrousek EF; Messing A
Hum Mol Genet; 2009 Apr; 18(7):1190-9. PubMed ID: 19129171
[TBL] [Abstract][Full Text] [Related]
3. STAT3 Drives GFAP Accumulation and Astrocyte Pathology in a Mouse Model of Alexander Disease.
Hagemann TL; Coyne S; Levin A; Wang L; Feany MB; Messing A
Cells; 2023 Mar; 12(7):. PubMed ID: 37048051
[TBL] [Abstract][Full Text] [Related]
4. Synemin is expressed in reactive astrocytes and Rosenthal fibers in Alexander disease.
Pekny T; Faiz M; Wilhelmsson U; Curtis MA; Matej R; Skalli O; Pekny M
APMIS; 2014 Jan; 122(1):76-80. PubMed ID: 23594359
[TBL] [Abstract][Full Text] [Related]
5. Glial fibrillary acidic protein exhibits altered turnover kinetics in a mouse model of Alexander disease.
Moody LR; Barrett-Wilt GA; Sussman MR; Messing A
J Biol Chem; 2017 Apr; 292(14):5814-5824. PubMed ID: 28223355
[TBL] [Abstract][Full Text] [Related]
6. Alexander disease-associated glial fibrillary acidic protein mutations in mice induce Rosenthal fiber formation and a white matter stress response.
Hagemann TL; Connor JX; Messing A
J Neurosci; 2006 Oct; 26(43):11162-73. PubMed ID: 17065456
[TBL] [Abstract][Full Text] [Related]
7. Aberrant astrocyte Ca
Saito K; Shigetomi E; Yasuda R; Sato R; Nakano M; Tashiro K; Tanaka KF; Ikenaka K; Mikoshiba K; Mizuta I; Yoshida T; Nakagawa M; Mizuno T; Koizumi S
Glia; 2018 May; 66(5):1053-1067. PubMed ID: 29383757
[TBL] [Abstract][Full Text] [Related]
8. The origin of Rosenthal fibers and their contributions to astrocyte pathology in Alexander disease.
Sosunov AA; McKhann GM; Goldman JE
Acta Neuropathol Commun; 2017 Mar; 5(1):27. PubMed ID: 28359321
[TBL] [Abstract][Full Text] [Related]
9. Plectin regulates the organization of glial fibrillary acidic protein in Alexander disease.
Tian R; Gregor M; Wiche G; Goldman JE
Am J Pathol; 2006 Mar; 168(3):888-97. PubMed ID: 16507904
[TBL] [Abstract][Full Text] [Related]
10. Relative stabilities of wild-type and mutant glial fibrillary acidic protein in patients with Alexander disease.
Heaven MR; Wilson L; Barnes S; Brenner M
J Biol Chem; 2019 Oct; 294(43):15604-15612. PubMed ID: 31484723
[TBL] [Abstract][Full Text] [Related]
11. GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease.
Li L; Tian E; Chen X; Chao J; Klein J; Qu Q; Sun G; Sun G; Huang Y; Warden CD; Ye P; Feng L; Li X; Cui Q; Sultan A; Douvaras P; Fossati V; Sanjana NE; Riggs AD; Shi Y
Cell Stem Cell; 2018 Aug; 23(2):239-251.e6. PubMed ID: 30075130
[TBL] [Abstract][Full Text] [Related]
12. Microglia sense astrocyte dysfunction and prevent disease progression in an Alexander disease model.
Saito K; Shigetomi E; Shinozaki Y; Kobayashi K; Parajuli B; Kubota Y; Sakai K; Miyakawa M; Horiuchi H; Nabekura J; Koizumi S
Brain; 2024 Feb; 147(2):698-716. PubMed ID: 37955589
[TBL] [Abstract][Full Text] [Related]
13. Elevated GFAP isoform expression promotes protein aggregation and compromises astrocyte function.
Lin NH; Yang AW; Chang CH; Perng MD
FASEB J; 2021 May; 35(5):e21614. PubMed ID: 33908669
[TBL] [Abstract][Full Text] [Related]
14. Metabolic Enzyme Alterations and Astrocyte Dysfunction in a Murine Model of Alexander Disease With Severe Reactive Gliosis.
Heaven MR; Herren AW; Flint DL; Pacheco NL; Li J; Tang A; Khan F; Goldman JE; Phinney BS; Olsen ML
Mol Cell Proteomics; 2022 Jan; 21(1):100180. PubMed ID: 34808356
[TBL] [Abstract][Full Text] [Related]
15. Phenotypic conversions of "protoplasmic" to "reactive" astrocytes in Alexander disease.
Sosunov AA; Guilfoyle E; Wu X; McKhann GM; Goldman JE
J Neurosci; 2013 Apr; 33(17):7439-50. PubMed ID: 23616550
[TBL] [Abstract][Full Text] [Related]
16. Site-specific phosphorylation and caspase cleavage of GFAP are new markers of Alexander disease severity.
Battaglia RA; Beltran AS; Delic S; Dumitru R; Robinson JA; Kabiraj P; Herring LE; Madden VJ; Ravinder N; Willems E; Newman RA; Quinlan RA; Goldman JE; Perng MD; Inagaki M; Snider NT
Elife; 2019 Nov; 8():. PubMed ID: 31682229
[TBL] [Abstract][Full Text] [Related]
17. Aggregation-prone GFAP mutation in Alexander disease validated using a zebrafish model.
Lee SH; Nam TS; Kim KH; Kim JH; Yoon W; Heo SH; Kim MJ; Shin BA; Perng MD; Choy HE; Jo J; Kim MK; Choi SY
BMC Neurol; 2017 Sep; 17(1):175. PubMed ID: 28882119
[TBL] [Abstract][Full Text] [Related]
18. Genetic ablation of Nrf2/antioxidant response pathway in Alexander disease mice reduces hippocampal gliosis but does not impact survival.
Hagemann TL; Jobe EM; Messing A
PLoS One; 2012; 7(5):e37304. PubMed ID: 22693571
[TBL] [Abstract][Full Text] [Related]
19. Antisense suppression of glial fibrillary acidic protein as a treatment for Alexander disease.
Hagemann TL; Powers B; Mazur C; Kim A; Wheeler S; Hung G; Swayze E; Messing A
Ann Neurol; 2018 Jan; 83(1):27-39. PubMed ID: 29226998
[TBL] [Abstract][Full Text] [Related]
20. The Alexander disease-causing glial fibrillary acidic protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alpha B-crystallin and HSP27.
Der Perng M; Su M; Wen SF; Li R; Gibbon T; Prescott AR; Brenner M; Quinlan RA
Am J Hum Genet; 2006 Aug; 79(2):197-213. PubMed ID: 16826512
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
