263 related articles for article (PubMed ID: 33688831)
1. eIF2B conformation and assembly state regulate the integrated stress response.
Schoof M; Boone M; Wang L; Lawrence R; Frost A; Walter P
Elife; 2021 Mar; 10():. PubMed ID: 33688831
[TBL] [Abstract][Full Text] [Related]
2. ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.
Zyryanova AF; Kashiwagi K; Rato C; Harding HP; Crespillo-Casado A; Perera LA; Sakamoto A; Nishimoto M; Yonemochi M; Shirouzu M; Ito T; Ron D
Mol Cell; 2021 Jan; 81(1):88-103.e6. PubMed ID: 33220178
[TBL] [Abstract][Full Text] [Related]
3. eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Kenner LR; Anand AA; Nguyen HC; Myasnikov AG; Klose CJ; McGeever LA; Tsai JC; Miller-Vedam LE; Walter P; Frost A
Science; 2019 May; 364(6439):491-495. PubMed ID: 31048491
[TBL] [Abstract][Full Text] [Related]
4. A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation.
Boone M; Wang L; Lawrence RE; Frost A; Walter P; Schoof M
Elife; 2022 Apr; 11():. PubMed ID: 35416150
[TBL] [Abstract][Full Text] [Related]
5. Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B.
Schoof M; Wang L; Cogan JZ; Lawrence RE; Boone M; Wuerth JD; Frost A; Walter P
Nat Commun; 2021 Dec; 12(1):7103. PubMed ID: 34876554
[TBL] [Abstract][Full Text] [Related]
6. eIF2B and the Integrated Stress Response: A Structural and Mechanistic View.
Marintchev A; Ito T
Biochemistry; 2020 Apr; 59(13):1299-1308. PubMed ID: 32200625
[TBL] [Abstract][Full Text] [Related]
7. Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule.
Tsai JC; Miller-Vedam LE; Anand AA; Jaishankar P; Nguyen HC; Renslo AR; Frost A; Walter P
Science; 2018 Mar; 359(6383):. PubMed ID: 29599213
[TBL] [Abstract][Full Text] [Related]
8. A C-term truncated EIF2Bγ protein encoded by an intronically polyadenylated isoform introduces unfavorable EIF2Bγ-EIF2γ interactions.
Circir A; Koksal Bicakci G; Savas B; Doken DN; Henden ŞO; Can T; Karaca E; Erson-Bensan AE
Proteins; 2022 Mar; 90(3):889-897. PubMed ID: 34796993
[TBL] [Abstract][Full Text] [Related]
9. Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.
Zyryanova AF; Weis F; Faille A; Alard AA; Crespillo-Casado A; Sekine Y; Harding HP; Allen F; Parts L; Fromont C; Fischer PM; Warren AJ; Ron D
Science; 2018 Mar; 359(6383):1533-1536. PubMed ID: 29599245
[TBL] [Abstract][Full Text] [Related]
10. Structural insights into ISRIB, a memory-enhancing inhibitor of the integrated stress response.
Anand AA; Walter P
FEBS J; 2020 Jan; 287(2):239-245. PubMed ID: 31550413
[TBL] [Abstract][Full Text] [Related]
11. Small molecule ISRIB suppresses the integrated stress response within a defined window of activation.
Rabouw HH; Langereis MA; Anand AA; Visser LJ; de Groot RJ; Walter P; van Kuppeveld FJM
Proc Natl Acad Sci U S A; 2019 Feb; 116(6):2097-2102. PubMed ID: 30674674
[TBL] [Abstract][Full Text] [Related]
12. Protection of eIF2B from inhibitory phosphorylated eIF2: A viral strategy to maintain mRNA translation during the PKR-triggered integrated stress response.
Ito T; Wuerth JD; Weber F
J Biol Chem; 2023 Nov; 299(11):105287. PubMed ID: 37742919
[TBL] [Abstract][Full Text] [Related]
13. Structural basis for eIF2B inhibition in integrated stress response.
Kashiwagi K; Yokoyama T; Nishimoto M; Takahashi M; Sakamoto A; Yonemochi M; Shirouzu M; Ito T
Science; 2019 May; 364(6439):495-499. PubMed ID: 31048492
[TBL] [Abstract][Full Text] [Related]
14. eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Kashiwagi K; Shichino Y; Osaki T; Sakamoto A; Nishimoto M; Takahashi M; Mito M; Weber F; Ikeuchi Y; Iwasaki S; Ito T
Nat Commun; 2021 Dec; 12(1):7102. PubMed ID: 34876589
[TBL] [Abstract][Full Text] [Related]
15. Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation.
Krishnamoorthy T; Pavitt GD; Zhang F; Dever TE; Hinnebusch AG
Mol Cell Biol; 2001 Aug; 21(15):5018-30. PubMed ID: 11438658
[TBL] [Abstract][Full Text] [Related]
16. Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response.
Sidrauski C; Tsai JC; Kampmann M; Hearn BR; Vedantham P; Jaishankar P; Sokabe M; Mendez AS; Newton BW; Tang EL; Verschueren E; Johnson JR; Krogan NJ; Fraser CS; Weissman JS; Renslo AR; Walter P
Elife; 2015 Apr; 4():e07314. PubMed ID: 25875391
[TBL] [Abstract][Full Text] [Related]
17. eIF2B Mechanisms of Action and Regulation: A Thermodynamic View.
Bogorad AM; Lin KY; Marintchev A
Biochemistry; 2018 Mar; 57(9):1426-1435. PubMed ID: 29425030
[TBL] [Abstract][Full Text] [Related]
18. Novel mechanisms of eIF2B action and regulation by eIF2α phosphorylation.
Bogorad AM; Lin KY; Marintchev A
Nucleic Acids Res; 2017 Nov; 45(20):11962-11979. PubMed ID: 29036434
[TBL] [Abstract][Full Text] [Related]
19. Regulation of translation initiation factor eIF2B at the hub of the integrated stress response.
Pavitt GD
Wiley Interdiscip Rev RNA; 2018 Nov; 9(6):e1491. PubMed ID: 29989343
[TBL] [Abstract][Full Text] [Related]
20. The small molecule ISRIB rescues the stability and activity of Vanishing White Matter Disease eIF2B mutant complexes.
Wong YL; LeBon L; Edalji R; Lim HB; Sun C; Sidrauski C
Elife; 2018 Feb; 7():. PubMed ID: 29489452
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
