BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

703 related articles for article (PubMed ID: 33691555)

  • 1. Activation of Nrf2 signaling pathway by natural and synthetic chalcones: a therapeutic road map for oxidative stress.
    Egbujor MC; Saha S; Buttari B; Profumo E; Saso L
    Expert Rev Clin Pharmacol; 2021 Apr; 14(4):465-480. PubMed ID: 33691555
    [No Abstract]   [Full Text] [Related]  

  • 2. The Keap1/Nrf2-ARE Pathway as a Pharmacological Target for Chalcones.
    de Freitas Silva M; Pruccoli L; Morroni F; Sita G; Seghetti F; Viegas C; Tarozzi A
    Molecules; 2018 Jul; 23(7):. PubMed ID: 30037040
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sofalcone, a gastroprotective drug, covalently binds to KEAP1 to activate Nrf2 resulting in anti-colitic activity.
    Kim W; Lee H; Kim S; Joo S; Jeong S; Yoo JW; Jung Y
    Eur J Pharmacol; 2019 Dec; 865():172722. PubMed ID: 31614142
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The chalcone compound isosalipurposide (ISPP) exerts a cytoprotective effect against oxidative injury via Nrf2 activation.
    Han JY; Cho SS; Yang JH; Kim KM; Jang CH; Park DE; Bang JS; Jung YS; Ki SH
    Toxicol Appl Pharmacol; 2015 Aug; 287(1):77-85. PubMed ID: 26028482
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.
    Giudice A; Arra C; Turco MC
    Methods Mol Biol; 2010; 647():37-74. PubMed ID: 20694660
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Licochalcone E activates Nrf2/antioxidant response element signaling pathway in both neuronal and microglial cells: therapeutic relevance to neurodegenerative disease.
    Kim SS; Lim J; Bang Y; Gal J; Lee SU; Cho YC; Yoon G; Kang BY; Cheon SH; Choi HJ
    J Nutr Biochem; 2012 Oct; 23(10):1314-23. PubMed ID: 22227268
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amelioration of Oxidative Stress in Caco-2 Cells Treated with Pro-inflammatory Proteins by Chlorogenic Acid Isomers via Activation of the Nrf2-Keap1-ARE-Signaling Pathway.
    Liang N; Kitts DD
    J Agric Food Chem; 2018 Oct; 66(42):11008-11017. PubMed ID: 30259744
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Keap1-Nrf2 signaling pathway: mechanisms of regulation and role in protection of cells against toxicity caused by xenobiotics and electrophiles.
    Turpaev KT
    Biochemistry (Mosc); 2013 Feb; 78(2):111-26. PubMed ID: 23581983
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An Overview of NRF2-Activating Compounds Bearing α,β-Unsaturated Moiety and Their Antioxidant Effects.
    Egbujor MC; Buttari B; Profumo E; Telkoparan-Akillilar P; Saso L
    Int J Mol Sci; 2022 Jul; 23(15):. PubMed ID: 35955599
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 4-methoxychalcone enhances cisplatin-induced oxidative stress and cytotoxicity by inhibiting the Nrf2/ARE-mediated defense mechanism in A549 lung cancer cells.
    Lim J; Lee SH; Cho S; Lee IS; Kang BY; Choi HJ
    Mol Cells; 2013 Oct; 36(4):340-6. PubMed ID: 24046186
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Isoliquiritigenin in licorice functions as a hepatic protectant by induction of antioxidant genes through extracellular signal-regulated kinase-mediated NF-E2-related factor-2 signaling pathway.
    Park SM; Lee JR; Ku SK; Cho IJ; Byun SH; Kim SC; Park SJ; Kim YW
    Eur J Nutr; 2016 Dec; 55(8):2431-2444. PubMed ID: 26593436
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isoliquiritigenin Provides Protection and Attenuates Oxidative Stress-Induced Injuries via the Nrf2-ARE Signaling Pathway After Traumatic Brain Injury.
    Zhang M; Huang LL; Teng CH; Wu FF; Ge LY; Shi YJ; He ZL; Liu L; Jiang CJ; Hou RN; Xiao J; Zhang HY; Chen DQ
    Neurochem Res; 2018 Dec; 43(12):2435-2445. PubMed ID: 30446968
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lico A Enhances Nrf2-Mediated Defense Mechanisms against t-BHP-Induced Oxidative Stress and Cell Death via Akt and ERK Activation in RAW 264.7 Cells.
    Lv H; Ren H; Wang L; Chen W; Ci X
    Oxid Med Cell Longev; 2015; 2015():709845. PubMed ID: 26576227
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure based modification of chalcone analogue activates Nrf2 in the human retinal pigment epithelial cell line ARPE-19.
    Cui Y; Li Y; Huang N; Xiong Y; Cao R; Meng L; Liu J; Feng Z
    Free Radic Biol Med; 2020 Feb; 148():52-59. PubMed ID: 31887452
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recent progress in the development of small molecule Nrf2 activators: a patent review (2017-present).
    Zhou H; Wang Y; You Q; Jiang Z
    Expert Opin Ther Pat; 2020 Mar; 30(3):209-225. PubMed ID: 31922884
    [No Abstract]   [Full Text] [Related]  

  • 16. Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease.
    Ahuja M; Ammal Kaidery N; Yang L; Calingasan N; Smirnova N; Gaisin A; Gaisina IN; Gazaryan I; Hushpulian DM; Kaddour-Djebbar I; Bollag WB; Morgan JC; Ratan RR; Starkov AA; Beal MF; Thomas B
    J Neurosci; 2016 Jun; 36(23):6332-51. PubMed ID: 27277809
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cardamonin protects against doxorubicin-induced cardiotoxicity in mice by restraining oxidative stress and inflammation associated with Nrf2 signaling.
    Qi W; Boliang W; Xiaoxi T; Guoqiang F; Jianbo X; Gang W
    Biomed Pharmacother; 2020 Feb; 122():109547. PubMed ID: 31918264
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of Nrf2-driven antioxidant enzymes by cardamonin confers neuroprotection of PC12 cells against oxidative damage.
    Peng S; Hou Y; Yao J; Fang J
    Food Funct; 2017 Mar; 8(3):997-1007. PubMed ID: 28271112
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Isoflavone biochanin A, a novel nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element activator, protects against oxidative damage in HepG2 cells.
    Liang F; Cao W; Huang Y; Fang Y; Cheng Y; Pan S; Xu X
    Biofactors; 2019 Jul; 45(4):563-574. PubMed ID: 31131946
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nuclear factor erythroid 2-related factor 2 signaling in Parkinson disease: a promising multi therapeutic target against oxidative stress, neuroinflammation and cell death.
    Kumar H; Koppula S; Kim IS; More SV; Kim BW; Choi DK
    CNS Neurol Disord Drug Targets; 2012 Dec; 11(8):1015-29. PubMed ID: 23244425
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.