BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

359 related articles for article (PubMed ID: 33692360)

  • 1. Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes.
    Tremel S; Ohashi Y; Morado DR; Bertram J; Perisic O; Brandt LTL; von Wrisberg MK; Chen ZA; Maslen SL; Kovtun O; Skehel M; Rappsilber J; Lang K; Munro S; Briggs JAG; Williams RL
    Nat Commun; 2021 Mar; 12(1):1564. PubMed ID: 33692360
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex.
    McKnight NC; Zhong Y; Wold MS; Gong S; Phillips GR; Dou Z; Zhao Y; Heintz N; Zong WX; Yue Z
    PLoS Genet; 2014 Oct; 10(10):e1004626. PubMed ID: 25275521
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NRBF2 regulates macroautophagy as a component of Vps34 Complex I.
    Cao Y; Wang Y; Abi Saab WF; Yang F; Pessin JE; Backer JM
    Biochem J; 2014 Jul; 461(2):315-22. PubMed ID: 24785657
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic.
    Thoresen SB; Pedersen NM; Liestøl K; Stenmark H
    Exp Cell Res; 2010 Dec; 316(20):3368-78. PubMed ID: 20643123
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes.
    Rostislavleva K; Soler N; Ohashi Y; Zhang L; Pardon E; Burke JE; Masson GR; Johnson C; Steyaert J; Ktistakis NT; Williams RL
    Science; 2015 Oct; 350(6257):aac7365. PubMed ID: 26450213
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG.
    Itakura E; Kishi C; Inoue K; Mizushima N
    Mol Biol Cell; 2008 Dec; 19(12):5360-72. PubMed ID: 18843052
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Vps34 Kinase Domain Dynamics Regulate the Autophagic PI 3-Kinase Complex.
    Stjepanovic G; Baskaran S; Lin MG; Hurley JH
    Mol Cell; 2017 Aug; 67(3):528-534.e3. PubMed ID: 28757208
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The G-Protein Rab5A Activates VPS34 Complex II, a Class III PI3K, by a Dual Regulatory Mechanism.
    Buckles TC; Ohashi Y; Tremel S; McLaughlin SH; Pardon E; Steyaert J; Gordon MT; Williams RL; Falke JJ
    Biophys J; 2020 Dec; 119(11):2205-2218. PubMed ID: 33137306
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The VPS34 PI3K negatively regulates RAB-5 during endosome maturation.
    Law F; Seo JH; Wang Z; DeLeon JL; Bolis Y; Brown A; Zong WX; Du G; Rocheleau CE
    J Cell Sci; 2017 Jun; 130(12):2007-2017. PubMed ID: 28455411
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CMTM7 as a novel molecule of ATG14L-Beclin1-VPS34 complex enhances autophagy by Rab5 to regulate tumorigenicity.
    Liu B; Lu Y; Zhang T; Yu X; Wang Q; Chi Y; Jin S; Cheng G
    Cell Commun Signal; 2021 Jul; 19(1):77. PubMed ID: 34281589
    [TBL] [Abstract][Full Text] [Related]  

  • 11. VPS34 complexes from a structural perspective.
    Ohashi Y; Tremel S; Williams RL
    J Lipid Res; 2019 Feb; 60(2):229-241. PubMed ID: 30397185
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels.
    Zhong Y; Morris DH; Jin L; Patel MS; Karunakaran SK; Fu YJ; Matuszak EA; Weiss HL; Chait BT; Wang QJ
    J Biol Chem; 2014 Sep; 289(38):26021-26037. PubMed ID: 25086043
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ehrlichia secretes Etf-1 to induce autophagy and capture nutrients for its growth through RAB5 and class III phosphatidylinositol 3-kinase.
    Lin M; Liu H; Xiong Q; Niu H; Cheng Z; Yamamoto A; Rikihisa Y
    Autophagy; 2016 Nov; 12(11):2145-2166. PubMed ID: 27541856
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation Mechanisms of the VPS34 Complexes.
    Ohashi Y
    Cells; 2021 Nov; 10(11):. PubMed ID: 34831348
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RACK1 Promotes Autophagy by Enhancing the Atg14L-Beclin 1-Vps34-Vps15 Complex Formation upon Phosphorylation by AMPK.
    Zhao Y; Wang Q; Qiu G; Zhou S; Jing Z; Wang J; Wang W; Cao J; Han K; Cheng Q; Shen B; Chen Y; Zhang WJ; Ma Y; Zhang J
    Cell Rep; 2015 Nov; 13(7):1407-1417. PubMed ID: 26549445
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency.
    Compton LM; Ikonomov OC; Sbrissa D; Garg P; Shisheva A
    Am J Physiol Cell Physiol; 2016 Sep; 311(3):C366-77. PubMed ID: 27335171
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Vps34 regulates Rab7 and late endocytic trafficking through recruitment of the GTPase-activating protein Armus.
    Jaber N; Mohd-Naim N; Wang Z; DeLeon JL; Kim S; Zhong H; Sheshadri N; Dou Z; Edinger AL; Du G; Braga VM; Zong WX
    J Cell Sci; 2016 Dec; 129(23):4424-4435. PubMed ID: 27793976
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex.
    Zhong Y; Wang QJ; Li X; Yan Y; Backer JM; Chait BT; Heintz N; Yue Z
    Nat Cell Biol; 2009 Apr; 11(4):468-76. PubMed ID: 19270693
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphoproteomic identification of ULK substrates reveals VPS15-dependent ULK/VPS34 interplay in the regulation of autophagy.
    Mercer TJ; Ohashi Y; Boeing S; Jefferies HBJ; De Tito S; Flynn H; Tremel S; Zhang W; Wirth M; Frith D; Snijders AP; Williams RL; Tooze SA
    EMBO J; 2021 Jul; 40(14):e105985. PubMed ID: 34121209
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Beclin 1 network regulates autophagy and apoptosis.
    Kang R; Zeh HJ; Lotze MT; Tang D
    Cell Death Differ; 2011 Apr; 18(4):571-80. PubMed ID: 21311563
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.