These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 33713780)

  • 1. Discovery of a novel series of guanidinebenzoates as gut-restricted enteropeptidase and trypsin dual inhibitors for the treatment of metabolic syndrome.
    Zhang X; Zhu B; Sun W; Wang M; Albarazanji K; Ghosh B; Cummings M; Lenhard J; Leonard J; Macielag M; Lanter J
    Bioorg Med Chem Lett; 2021 May; 40():127939. PubMed ID: 33713780
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enteropeptidase inhibition improves obesity by modulating gut microbiota composition and enterobacterial metabolites in diet-induced obese mice.
    Sugama J; Moritoh Y; Yashiro H; Tsuchimori K; Watanabe M
    Pharmacol Res; 2021 Jan; 163():105337. PubMed ID: 33276106
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SCO-792, an enteropeptidase inhibitor, improves disease status of diabetes and obesity in mice.
    Yashiro H; Hamagami K; Hiyoshi H; Sugama J; Tsuchimori K; Yamaguchi F; Moritoh Y; Sasaki M; Maekawa T; Yamada Y; Watanabe M
    Diabetes Obes Metab; 2019 Oct; 21(10):2228-2239. PubMed ID: 31144422
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, Synthesis, and Biological Evaluation of a Novel Series of 4-Guanidinobenzoate Derivatives as Enteropeptidase Inhibitors with Low Systemic Exposure for the Treatment of Obesity.
    Ikeda Z; Kakegawa K; Kikuchi F; Itono S; Oki H; Yashiro H; Hiyoshi H; Tsuchimori K; Hamagami K; Watanabe M; Sasaki M; Ishihara Y; Tohyama K; Kitazaki T; Maekawa T; Sasaki M
    J Med Chem; 2022 Jun; 65(12):8456-8477. PubMed ID: 35686954
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting Enteropeptidase with Reversible Covalent Inhibitors To Achieve Metabolic Benefits.
    Sun W; Zhang X; Cummings MD; Albarazanji K; Wu J; Wang M; Alexander R; Zhu B; Zhang Y; Leonard J; Lanter J; Lenhard J
    J Pharmacol Exp Ther; 2020 Dec; 375(3):510-521. PubMed ID: 33033171
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of trypsin and urokinase by Cbz-amino(4-guanidinophenyl)methanephosphonate aromatic ester derivatives: the influence of the ester group on their biological activity.
    Sieńczyk M; Oleksyszyn J
    Bioorg Med Chem Lett; 2006 Jun; 16(11):2886-90. PubMed ID: 16546384
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and structure activity relationship of guanidines as NPY Y5 antagonists.
    Aquino CJ; Ramanjulu JM; Heyer D; Daniels AJ; Palazzo F; Dezube M
    Bioorg Med Chem; 2004 May; 12(10):2691-708. PubMed ID: 15110851
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [An inhibitor of enteropeptidases and trypsin from the bovine duodenum].
    Mikhaĭlova AG; Evtiukova NG; Chupova LA; Rumsh LD
    Vopr Med Khim; 1998; 44(4):338-46. PubMed ID: 9845920
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Trypsin inhibitors: promising candidate satietogenic proteins as complementary treatment for obesity and metabolic disorders?
    Cristina Oliveira de Lima V; Piuvezam G; Leal Lima Maciel B; Heloneida de Araújo Morais A
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):405-419. PubMed ID: 30734596
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery and characterization of a small-molecule enteropeptidase inhibitor, SCO-792.
    Sasaki M; Miyahisa I; Itono S; Yashiro H; Hiyoshi H; Tsuchimori K; Hamagami KI; Moritoh Y; Watanabe M; Tohyama K; Sasaki M; Sakamoto JI; Kawamoto T
    Pharmacol Res Perspect; 2019 Oct; 7(5):e00517. PubMed ID: 31508234
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inactivation of trypsin-like proteases by depsipeptides of p-guanidinobenzoic acid.
    Ganu VS; Shaw E
    J Med Chem; 1981 Jun; 24(6):698-700. PubMed ID: 6454782
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and inhibition of human acrosin and trypsin and acute toxicity of aryl 4-guanidinobenzoates.
    Kaminski JM; Bauer L; Mack SR; Anderson RA; Waller DP; Zaneveld LJ
    J Med Chem; 1986 Apr; 29(4):514-9. PubMed ID: 3514912
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Potent thrombin inhibitors that probe the S1 subsite: tripeptide transition state analogues based on a heterocycle-activated carbonyl group.
    Costanzo MJ; Maryanoff BE; Hecker LR; Schott MR; Yabut SC; Zhang HC; Andrade-Gordon P; Kauffman JA; Lewis JM; Krishnan R; Tulinsky A
    J Med Chem; 1996 Aug; 39(16):3039-43. PubMed ID: 8759623
    [No Abstract]   [Full Text] [Related]  

  • 14. Effect of low-molecular weight trypsin inhibitor, nafamostat mesilate, on trypsin activity using the pancreatic acinar cells.
    Hashimoto D; Ohmuraya M; Wang J; Yamamura K; Hirota M; Baba H
    Pancreas; 2009 Jul; 38(5):595-7. PubMed ID: 19550278
    [No Abstract]   [Full Text] [Related]  

  • 15. Discovery of a novel series of medium-sized cyclic enteropeptidase inhibitors.
    Kikuchi F; Ikeda Z; Kakegawa K; Nishikawa Y; Sasaki S; Fukuda K; Takami K; Banno Y; Nishikawa H; Taya N; Nakahata T; Itono S; Yashiro H; Tsuchimori K; Hiyoshi H; Sasaki M; Tohyama K; Matsumiya K; Ishihara Y; Kawamoto T; Kamaura M; Watanabe M; Kitazaki T; Maekawa T; Sasaki M
    Bioorg Med Chem; 2023 Oct; 93():117462. PubMed ID: 37683572
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression, purification, and characterization of human enteropeptidase catalytic subunit in Escherichia coli.
    Gasparian ME; Ostapchenko VG; Schulga AA; Dolgikh DA; Kirpichnikov MP
    Protein Expr Purif; 2003 Sep; 31(1):133-9. PubMed ID: 12963350
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Further evidence for an active center in streptokinase-plasminogen complex; interaction with pancreatic trypsin inhibitor.
    Reddy KN; Markus G
    Biochem Biophys Res Commun; 1973 Apr; 51(3):672-9. PubMed ID: 4267404
    [No Abstract]   [Full Text] [Related]  

  • 18. Evidence that the two binding sites for trypsin on chicken ovoinhibitor are not equivalent. Dissociation of the complexes with porcine trypsin.
    Zahnley JC
    J Biol Chem; 1974 Jul; 249(13):4282-5. PubMed ID: 4851943
    [No Abstract]   [Full Text] [Related]  

  • 19. Bovine proenteropeptidase is activated by trypsin, and the specificity of enteropeptidase depends on the heavy chain.
    Lu D; Yuan X; Zheng X; Sadler JE
    J Biol Chem; 1997 Dec; 272(50):31293-300. PubMed ID: 9395456
    [TBL] [Abstract][Full Text] [Related]  

  • 20. "Inverse" type of synthetic inhibitors of trypsin, S-omega-aminoalkyl thioesters.
    Kunieda T; Ishizuka T; Hirobe M
    Chem Pharm Bull (Tokyo); 1983 Sep; 31(9):3360-2. PubMed ID: 6667544
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 6.